LOCUS       CAB5247937.1             576 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED TRANSMEMBRANE PROTEIN protein.
ACCESSION   LT708304-236
PROTEIN_ID  CAB5247937.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0231C"
                     /note="Mb0231c, -, len: 576 aa. Equivalent to Rv0226c,
                     len: 576 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 576 aa overlap). Probable conserved
                     transmembrane protein, equivalent, except in N-terminal
                     part, to AC32114.1|AL583926 conserved membrane protein
                     from Mycobacterium leprae (600 aa), FASTA scores: opt:
                     2086, E(): 0, (70.3% identity in 579 aa overlap). Also
                     similar to AL021411|SC7H1_20 from Streptomyces coelicolor
                     (483 aa), FASTA scores: opt: 180, E(): 0.00028, (26.5
                     identity in 388 aa overlap). Protein product from Mb0231c
                     detected using SWATH mass spectrometry. Mb0231c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MRWFRPGYAL VLVLLLAAPL LRPGYLLLRD AVSTPRSYVS ANALGLTSAP RATPQDFAVA
       61 LASHLVDGGV VVKALLLLGL WLAGWGAARL VATALPAAGA AGQFVAITLA IWNPYVAERL
      121 LQGHWSLLVG YGCLPWVATA MLTMRTTVGA GWFGLFGLAF WVALAGLTPS GLLLAATVAV
      181 VCVAMPGAGR PRWQCGVAAL GSALVGALPW LTASALGSSL TSHTAANQLG VTAFAPRAEP
      241 GLGTLGSLAS LGGIWNGEAV PSSRTTLFAV ASAVVLLAMV AIGLPTVARR PVAVPLLTLA
      301 AVSVMVPAVL ATGPGLHALR VVVDAAPGLG VLRDGQKWVA LAVPGYTLSG AGTVLTLRRW
      361 LRPATAAVVC CLALVLTLPD LAWGVWGKVA PVHYPSGWAA VAAAINADPR TVAVLPAGTM
      421 RRFSWSGSAP VLDPLPRWVR ADVLTTGDLV ISGVTVPGED AHARAVQELL LTGPHPSTLA
      481 AAGVGWLVVE SDSAGDMGAA ARTLGRLAAA HRDDELALYR VGGQTSGASS ARLKATMLAH
      541 WAWLSMLLVG GAGAAGYWVR RHLHHCEDTP ASRAQD
//