LOCUS CAB5247937.1 576 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED TRANSMEMBRANE PROTEIN protein. ACCESSION LT708304-236 PROTEIN_ID CAB5247937.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0231C" /note="Mb0231c, -, len: 576 aa. Equivalent to Rv0226c, len: 576 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 576 aa overlap). Probable conserved transmembrane protein, equivalent, except in N-terminal part, to AC32114.1|AL583926 conserved membrane protein from Mycobacterium leprae (600 aa), FASTA scores: opt: 2086, E(): 0, (70.3% identity in 579 aa overlap). Also similar to AL021411|SC7H1_20 from Streptomyces coelicolor (483 aa), FASTA scores: opt: 180, E(): 0.00028, (26.5 identity in 388 aa overlap). Protein product from Mb0231c detected using SWATH mass spectrometry. Mb0231c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MRWFRPGYAL VLVLLLAAPL LRPGYLLLRD AVSTPRSYVS ANALGLTSAP RATPQDFAVA 61 LASHLVDGGV VVKALLLLGL WLAGWGAARL VATALPAAGA AGQFVAITLA IWNPYVAERL 121 LQGHWSLLVG YGCLPWVATA MLTMRTTVGA GWFGLFGLAF WVALAGLTPS GLLLAATVAV 181 VCVAMPGAGR PRWQCGVAAL GSALVGALPW LTASALGSSL TSHTAANQLG VTAFAPRAEP 241 GLGTLGSLAS LGGIWNGEAV PSSRTTLFAV ASAVVLLAMV AIGLPTVARR PVAVPLLTLA 301 AVSVMVPAVL ATGPGLHALR VVVDAAPGLG VLRDGQKWVA LAVPGYTLSG AGTVLTLRRW 361 LRPATAAVVC CLALVLTLPD LAWGVWGKVA PVHYPSGWAA VAAAINADPR TVAVLPAGTM 421 RRFSWSGSAP VLDPLPRWVR ADVLTTGDLV ISGVTVPGED AHARAVQELL LTGPHPSTLA 481 AAGVGWLVVE SDSAGDMGAA ARTLGRLAAA HRDDELALYR VGGQTSGASS ARLKATMLAH 541 WAWLSMLLVG GAGAAGYWVR RHLHHCEDTP ASRAQD //