LOCUS CAB5247935.1 254 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE METHYLTRANSFERASE (METHYLASE) protein. ACCESSION LT708304-234 PROTEIN_ID CAB5247935.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0229C" /note="Mb0229c, -, len: 254 aa. Equivalent to Rv0224c, len: 254 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 254 aa overlap). Possible methyltransferase (EC 2.1.1.-), showing weak similarity with other methyltransferases e.g. P74388 STEROL-C-METHYLTRANSFERASE (318 aa), FASTA scores: opt: 190, E(): 3.6e-05, (33.3% identity in 114 aa overlap). Equivalent to AL022486|MLCB1883_1 from Mycobacterium leprae (269 aa), FASTA scores: opt: 1456, E(): 0, (82.9% identity in 252 aa overlap). Also some similarity with MTCY21B4.22c from Mycobacterium tuberculosis FASTA score: (30.1% identity in 136 aa overlap). Mb0229c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MAVTDVFARR ATLRRSLRLL ADFRYEQRDP ARFYRTLAAD TAAMIGDLWL ATHSEPPVGR 61 TLLDVGGGPG YFATAFSDAG VGYIGVEPDP DEMHAAGPAF TGRPGMFVRA SGMALPLADD 121 SVDICLSSNV AEHVPRPWQL GTEMLRVTKP GGLVVLSYTV WLGPFGGHEM GLSHYLGGAR 181 AAARYVRKHG HPAKNNYGSS LFAVSAAEGL RWAAGTGAAL AVFPRYHPRW AWWLTSVPVL 241 REFLVSNLVL VLTP //