LOCUS       CAB5247935.1             254 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            METHYLTRANSFERASE (METHYLASE) protein.
ACCESSION   LT708304-234
PROTEIN_ID  CAB5247935.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0229C"
                     /note="Mb0229c, -, len: 254 aa. Equivalent to Rv0224c,
                     len: 254 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 254 aa overlap). Possible
                     methyltransferase (EC 2.1.1.-), showing weak similarity
                     with other methyltransferases e.g. P74388
                     STEROL-C-METHYLTRANSFERASE (318 aa), FASTA scores: opt:
                     190, E(): 3.6e-05, (33.3% identity in 114 aa overlap).
                     Equivalent to AL022486|MLCB1883_1 from Mycobacterium
                     leprae (269 aa), FASTA scores: opt: 1456, E(): 0, (82.9%
                     identity in 252 aa overlap). Also some similarity with
                     MTCY21B4.22c from Mycobacterium tuberculosis FASTA score:
                     (30.1% identity in 136 aa overlap). Mb0229c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MAVTDVFARR ATLRRSLRLL ADFRYEQRDP ARFYRTLAAD TAAMIGDLWL ATHSEPPVGR
       61 TLLDVGGGPG YFATAFSDAG VGYIGVEPDP DEMHAAGPAF TGRPGMFVRA SGMALPLADD
      121 SVDICLSSNV AEHVPRPWQL GTEMLRVTKP GGLVVLSYTV WLGPFGGHEM GLSHYLGGAR
      181 AAARYVRKHG HPAKNNYGSS LFAVSAAEGL RWAAGTGAAL AVFPRYHPRW AWWLTSVPVL
      241 REFLVSNLVL VLTP
//