LOCUS       CAB5247932.1             403 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ESTERASE LIPC protein.
ACCESSION   LT708304-231
PROTEIN_ID  CAB5247932.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lipC"
                     /locus_tag="BQ2027_MB0226"
                     /note="Mb0226, lipC, len: 403 aa. Equivalent to Rv0220,
                     len: 403 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 403 aa overlap). Probable esterase (EC
                     3.1.1.-), similar to others proteins and esterases from
                     various organisms and Mycobacterium tuberculosis e.g.
                     Q50681 (431 aa), FASTA scores: opt: 841, E(): 0, (38.2%
                     identity in 408 aa overlap); Rv1426c, Rv1399c, etc.
                     Contains PS00122 Carboxylesterases type-B serine active
                     site. Protein product from Mb0226 detected using SWATH
                     mass spectrometry. Mb0226 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MNQRRAAGST GVAYIRWLLR ARPADYMLAL SVAGGSLPVV GKHLKPLGGV TAIGVWGARH
       61 ASDFLSATAK DLLTPGINEV RRRDRASTQE VSVAALRGIV SPDDLAVEWP APERTPPVCG
      121 ALRHRRYVHR RRVLYGDDPA QLLDVWRRKD MPTKPAPVLI FVPGGAWVHG SRAIQGYAVL
      181 SRLAAQGWVC LSIDYRVAPH HRWPRHILDV KTAIAWARAN VDKFGGDRNF IAVAGCSAGG
      241 HLSALAGLTA NDPQYQAELP EGSDTSVDAV VGIYGRYDWE DRSTPERARF VDFLERVVVQ
      301 RTIDRHPEVF RDASPIQRVT RNAPPFLVIH GSRDCVIPVE QARSFVERLR AVSRSQVGYL
      361 ELPGAGHGFD LLDGARTGPT AHAIALFLNQ VHRSRAQFAK EVI
//