LOCUS CAB5247932.1 403 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE ESTERASE LIPC protein. ACCESSION LT708304-231 PROTEIN_ID CAB5247932.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lipC" /locus_tag="BQ2027_MB0226" /note="Mb0226, lipC, len: 403 aa. Equivalent to Rv0220, len: 403 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 403 aa overlap). Probable esterase (EC 3.1.1.-), similar to others proteins and esterases from various organisms and Mycobacterium tuberculosis e.g. Q50681 (431 aa), FASTA scores: opt: 841, E(): 0, (38.2% identity in 408 aa overlap); Rv1426c, Rv1399c, etc. Contains PS00122 Carboxylesterases type-B serine active site. Protein product from Mb0226 detected using SWATH mass spectrometry. Mb0226 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MNQRRAAGST GVAYIRWLLR ARPADYMLAL SVAGGSLPVV GKHLKPLGGV TAIGVWGARH 61 ASDFLSATAK DLLTPGINEV RRRDRASTQE VSVAALRGIV SPDDLAVEWP APERTPPVCG 121 ALRHRRYVHR RRVLYGDDPA QLLDVWRRKD MPTKPAPVLI FVPGGAWVHG SRAIQGYAVL 181 SRLAAQGWVC LSIDYRVAPH HRWPRHILDV KTAIAWARAN VDKFGGDRNF IAVAGCSAGG 241 HLSALAGLTA NDPQYQAELP EGSDTSVDAV VGIYGRYDWE DRSTPERARF VDFLERVVVQ 301 RTIDRHPEVF RDASPIQRVT RNAPPFLVIH GSRDCVIPVE QARSFVERLR AVSRSQVGYL 361 ELPGAGHGFD LLDGARTGPT AHAIALFLNQ VHRSRAQFAK EVI //