LOCUS       CAB5247929.1             302 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            ESTERASE LIPW protein.
ACCESSION   LT708304-228
PROTEIN_ID  CAB5247929.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lipW"
                     /locus_tag="BQ2027_MB0223C"
                     /note="Mb0223c, lipW, len: 302 aa. Equivalent to Rv0217c,
                     len: 302 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 302 aa overlap). Possible esterase (EC
                     3.1.1.-), showing similarity with others e.g.
                     EST_ACICA|P18773 esterase (303 aa), FASTA scores: opt:
                     320, E(): 3.2e-13, (29.2% identity in 274 aa overlap).
                     Protein product from Mb0223c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0223c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MSGNEVHPDL RRIAVVTPRQ LVGPRTLPVM RALIVVAGLR MSRTPPDIEV LTLESGVGVR
       61 LYRPAGSNEP APALLWIHAG GYVMGTAQQD DRLCLRFSSR LGITVASVDY RLAPENPYPA
      121 ALGDCYSALT WLASLPAVDP ARVAIGGASA GGGLAAALAL LARDRGGITP AFQLLVYPML
      181 DDRTSIAPAN PHYRLWNGRA NRFGWRAYLG DADARVAVPG RRDDLGGLAP AWIGVGTHDL
      241 LHDEDLAYAE RLTAAGVPCQ VEVVEGAFHG FDRVAPNVGV SQRFFTSQCN SLRAALALSN
      301 RT
//