LOCUS       CAB5247925.1             437 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            METHYLTRANSFERASE (METHYLASE) protein.
ACCESSION   LT708304-224
PROTEIN_ID  CAB5247925.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0219C"
                     /note="Mb0219c, -, len: 437 aa. Equivalent to Rv0213c,
                     len: 437 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 437 aa overlap). Possible
                     methyltransferase (EC 2.1.1.-), weakly similar to others
                     methyltransferases e.g. AF127374_30|LINA from Streptomyces
                     lavendulae (611 aa), FASTA scores: opt: 400, E(): 8.1e-19,
                     (27.3% identity in 388 aa overlap); Q50258 fortimicin kl1
                     methyltransferase (553 aa), FASTA scores: opt: 267, E():
                     1.2e-13, (29.3% identity in 351 aa overlap). Mb0219c found
                     to be expressed during exponential growth in Sauton's
                     minimal media by RNA-sequencing (TPM > 20)."
BEGIN
        1 MSIKAYAKTQ GIAVTSVNGL VAGHGSVQET WLAMQSAAAL SGTPRLVGFS CIDTFPEVLW
       61 LAQRARQAWD GVRIVIGNAM ATLNYERILR QHDCFDYVVV GDGEVAFTKL ALALANDAAV
      121 DDVPGLARRS EQGQILRTPS SLVDLDELPR PARDELPTVL ADGFAASVFS TRGCPYRCTF
      181 CGTGAMSAML GKDSYRAKSV DAVVDEIDYL VSDYDVNFLS ITDDLFISKH PGSQQRAADF
      241 ANAVLRRGIS VNFMVDIRLD SVVDLDLFKH LHRAGLRRVF IGVETGSYEQ LRAYRKQILT
      301 RGQDAADTIN ALQQLGIDVI PGTIMFHPTV QPDELRETVR LLRATKYTVG FKFMSRIVPY
      361 PGTPLYQAYS DAGYLTAKWP LGQWEFVDPE ASRVYADVVA KVAPDVGISF DEAEAYFLSR
      421 LDEWENVIAG RIAEATS
//