LOCUS       CAB5247924.1             323 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            TRANSCRIPTIONAL REGULATORY PROTEIN NADR (PROBABLY ASNC-
            FAMILY) protein.
ACCESSION   LT708304-223
PROTEIN_ID  CAB5247924.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="nadR"
                     /locus_tag="BQ2027_MB0218C"
                     /note="Mb0218c, nadR, len: 323 aa. Equivalent to Rv0212c,
                     len: 323 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 323 aa overlap). Possible nadR
                     (alternate gene name: nadI), transcriptional regulator,
                     similar to others e.g. NADR_ECOLI|P27278 transcriptional
                     regulator from Escherichia coli (410 aa), FASTA scores:
                     opt: 377, E (): 1e-17, (31.1% identity in 347 aa overlap).
                     Contains PS00017 ATP/GTP-binding site motif A (P-loop).
                     Protein product from Mb0218c detected using SWATH mass
                     spectrometry. Mb0218c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MTHGMVLGKF MPPHAGHVYL CEFARRWVDE LTIVVGSTAA EPIPGAQRVA WMRELFPFDR
       61 VVHLANENPQ RPWEHPDFWD IWKASLQGVL ATRPDFVFGA EPYNADFAQV LGARFVAVDH
      121 GRTVVPVTAT DIRADPLGHW QHIPRCVRPA FVKRVSIIGP ESTGKTTLAQ AVAEKLRTKW
      181 VPERAKMLRE LNGGSLIGLE WAEIVRGQIA SEEALARDAD RVLICDTDPL ATTVWAEFLA
      241 GGCPQELRDL ARRPYDLTLL TTPDVPWDAD DGRCVPGARG TFFARCEQAL RAAGRSFVVI
      301 TGGWEERLSV SLRAVEELVR ARR
//