LOCUS CAB5247924.1 323 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN NADR (PROBABLY ASNC- FAMILY) protein. ACCESSION LT708304-223 PROTEIN_ID CAB5247924.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="nadR" /locus_tag="BQ2027_MB0218C" /note="Mb0218c, nadR, len: 323 aa. Equivalent to Rv0212c, len: 323 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 323 aa overlap). Possible nadR (alternate gene name: nadI), transcriptional regulator, similar to others e.g. NADR_ECOLI|P27278 transcriptional regulator from Escherichia coli (410 aa), FASTA scores: opt: 377, E (): 1e-17, (31.1% identity in 347 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Protein product from Mb0218c detected using SWATH mass spectrometry. Mb0218c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MTHGMVLGKF MPPHAGHVYL CEFARRWVDE LTIVVGSTAA EPIPGAQRVA WMRELFPFDR 61 VVHLANENPQ RPWEHPDFWD IWKASLQGVL ATRPDFVFGA EPYNADFAQV LGARFVAVDH 121 GRTVVPVTAT DIRADPLGHW QHIPRCVRPA FVKRVSIIGP ESTGKTTLAQ AVAEKLRTKW 181 VPERAKMLRE LNGGSLIGLE WAEIVRGQIA SEEALARDAD RVLICDTDPL ATTVWAEFLA 241 GGCPQELRDL ARRPYDLTLL TTPDVPWDAD DGRCVPGARG TFFARCEQAL RAAGRSFVVI 301 TGGWEERLSV SLRAVEELVR ARR //