LOCUS       CAB5247920.1             263 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 HYPOTHETICAL
            METHLYTRANSFERASE (METHYLASE) protein.
ACCESSION   LT708304-219
PROTEIN_ID  CAB5247920.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0214C"
                     /note="Mb0214c, -, len: 263 aa. Equivalent to Rv0208c,
                     len: 263 aa, from Mycobacterium tuberculosis strain H37Rv
                     (100.0% identity in 263 aa overlap). Hypothetical
                     methyltransferase (EC 2.1.1.-), equivalent to
                     Z95398|MLCL622_20 from Mycobacterium leprae (279 aa),
                     FASTA score: (64.2% identity in 246 aa overlaps). Also
                     similar to others e.g.
                     10178368|CAC08407.1|AL392177|Q9F305|MT04_STRCO|SCD17A.03c
                     HYPOTHETICAL METHLYTRANSFERASE from Streptomyces
                     coelicolor (271 aa). Could start at aa 7. Protein product
                     from Mb0214c detected using SWATH mass spectrometry.
                     Mb0214c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
BEGIN
        1 MVHHGQMHAQ PGVGLRPDTP VASGQLPSTS IRSRRSGISK AQRETWERLW PELGLLALPQ
       61 SPRGTPVDTR AWFGRDAPVV LEIGSGSGTS TLAMAKAEPH VDVIAVDVYR RGLAQLLCAI
      121 DKVGSDGINI RLILGNAVDV LQHLIAPDSL CGVRVFFPDP WPKARHHKRR LLQPATMALI
      181 ADRLVPSGVL HAATDHPGYA EHIAAAGDAE PRLVRVDPDT ELLPISVVRP ATKYERKAQL
      241 GGGAVIELLW KKHGCSERDL KIR
//