LOCUS CAB5247916.1 427 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED TRANSMEMBRANE PROTEIN protein. ACCESSION LT708304-215 PROTEIN_ID CAB5247916.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0210C" /note="Mb0210c, -, len: 427 aa. Equivalent to Rv0204c, len: 412 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 412 aa overlap). Probable conserved transmembrane protein, equivalent, but has C-terminal extension, to Z95398|MLCL622.17c from Mycobacterium leprae (367 aa), FASTA scores: opt: 2002, E(): 0, (82.4% identity in 374 aa overlap). Some similarity to Rv0585c from Mycobacterium tuberculosis. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, the presence of a more likely start codon leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (427 a versus 412 aa). Mb0210c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MYRDYGATCT VTLKHVSHDA PARNLRQRVG ALPRTRVGAP PAEGVPPRGK YWWLRWAVLA 61 IVAIVLAIEV ALGWDQLAKA WVSLYRAKWW WLLAAVAAAG ASMHSFAQIQ RTLLKSAGVH 121 VKQWRSEAAF YAANSLSTTL PGGPVLSATF LLRQQRIWGA STVVASWQLV MSGVLQAVGL 181 ALLGLGGAFF LGAKNNPFSL LFTLGGFVTL LLLAQAVASR PELIEGIGRR VLSWANSVRG 241 RPADAGLPKW RETLMQLESV SLGRRDLGVA FGWSLFNWIA DVACLGFAAY AAGDHASVGG 301 LAVAYAAARA VGTIPLMPGG LLVVEAVLVP GLVSSGMPLP SAISAMLIYR LISWLLIAAI 361 GWVVFFFMFR TESTADSDND RDPPTDPNLR LVIQPQGTPC DDPVETTPQG PAPTPDLRPE 421 GGETPPR //