LOCUS       CAB5247900.1             143 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED TRANSMEMBRANE PROTEIN protein.
ACCESSION   LT708304-199
PROTEIN_ID  CAB5247900.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0194"
                     /note="Mb0194, -, len: 143 aa. Equivalent to Rv0188, len:
                     143 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 143 aa overlap). Probable conserved
                     transmembrane protein, similar to
                     T35347|4835334|CAB42956.1|AL049863|SC5H1_31 probable
                     membrane protein from Streptomyces coelicolor (147 aa),
                     FASTA scores: opt: 326, E(): 6.5e-15, (36.2% identity in
                     141 aa overlap); N-terminus of P80185|MTRC_METTH
                     TETRAHYDROMETHANOPTERIN S-METHYLTRANSFERASE SUBUNIT C (EC
                     2.1.1.86) from Methanobacterium thermoautotrophicum strain
                     Marburg/DSM 2133 (266 aa), FASTA scores: opt: 125, E():
                     0.033, (31.6% identity in 98 aa overlap). Also similar to
                     Rv3635 from Mycobacterium tuberculosis. Protein product
                     from Mb0194 detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb0194 found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MSTVHSSIDQ HPDLLALRAS FDRAAESTIA HFTFGLALLA GLYVAASPWI VGFSATRGLP
       61 TCDLIVGIAV AYLAYGFASA LDRTHGMTWT LPVLGVWVIF SPWVLPGVAV TAGMMWSHII
      121 AGAVVAVLGF YFGMRTRAAA NQG
//