LOCUS       CAB5247899.1             220 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            O-METHYLTRANSFERASE protein.
ACCESSION   LT708304-198
PROTEIN_ID  CAB5247899.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0193"
                     /note="Mb0193, -, len: 220 aa. Equivalent to Rv0187, len:
                     220 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 220 aa overlap). Probable
                     O-methyltransferase (EC 2.1.1.-), similar to many e.g.
                     AB93458.1|AL357591 putative O-methyltransferase from
                     Streptomyces coelicolor (223 aa); MDMC_STRMY|Q00719
                     O-methyltransferase from Streptomyces mycarofaciens (221
                     aa), FASTA scores: opt: 327, E(): 2.4e-17, (35.9% identity
                     in 192 aa overlap). Also similar to Rv1703c, Rv1220c from
                     Mycobacterium tuberculosis. Protein product from Mb0193
                     detected using shotgun mass spectrometry. Mb0193 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MGMDQQPNPP DVDAFLDSTL VGDDPALAAA LAASDAAELP RIAVSAQQGK FLCLLAGAIQ
       61 ARRVLEIGTL GGFSTIWLAR GAGPQGRVVT LEYQPKHAEV ARVNLQRAGV ADRVEVVVGP
      121 ALDTLPTLAG GPFDLVFIDA DKENNVAYIQ WAIRLARRGA VIVVDNVIRG GGILAESDDA
      181 DAVAARRTLQ MMGEHPGLDA TAIQTVGRKG WDGFALALVR
//