LOCUS       CAB5247890.1             369 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            lipoprotein lpro protein.
ACCESSION   LT708304-189
PROTEIN_ID  CAB5247890.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lprO"
                     /locus_tag="BQ2027_MB0185C"
                     /note="Mb0185c, lprO, len: 369 aa. Equivalent to Rv0179c,
                     len: 369 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 369 aa overlap). Possible lprO,
                     lipoprotein (visibly not conserved). Contains possible
                     N-terminal signal sequence and PS00013 Prokaryotic
                     membrane lipoprotein lipid attachment site. Protein
                     product from Mb0185c detected using SWATH mass
                     spectrometry. Mb0185c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MWIRAERVAV LTPTASLRRL TACYAALAVC AALACTTGQP AARAADGREM LAQAIATTRG
       61 SYLVYNFGGG HPMPLLNAGG HWYEMNNGGH LMIIKNASQR LSPHLLVDTH TGDQARCEHN
      121 PGAHTGEGLW QASEIYPPLK AWQRMGRPTI AVNANFFDVR GQKGGSWRST GCSSPLGAYV
      181 DNTRGQGRAN QAVTGTVAYA GKQGLSGGNE LWSSLTTMIL PVGGAPYVLR PKSRQDYDLA
      241 TPVIEDLLNK NARFVAVAGI GLLSPGNTGQ LHDGGPSAAR TALAYAKQKD EMYIFQGGNY
      301 TPDNIQDLFR GLGSDTAILL DGGGSSAIVL RRDTGGMWAG AGSPKGSCDT RQVLCDSHER
      361 ALPSWLAFN
//