LOCUS       CAB5247887.1             322 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED MCE ASSOCIATED TRANSMEMBRANE PROTEIN protein.
ACCESSION   LT708304-186
PROTEIN_ID  CAB5247887.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0182"
                     /note="Mb0182, -, len: 322 aa. Equivalent to Rv0176, len:
                     322 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.4% identity in 322 aa overlap). Probable conserved
                     Mce-associated transmembrane protein. Contains short
                     region of similarity to PRA_MYCLE|P41484 proline-rich
                     antigen (36 kDa antigen) from Mycobacterium leprae (249
                     aa) (outside the proline-rich region), FASTA scores: opt:
                     165, E(): 2.9e-05, (40.0% identity in 65 aa overlap). Also
                     similar to mce-associated proteins from Mycobacterium
                     tuberculosis e.g. Rv1363c, Rv0177, Rv3493c, etc. Protein
                     product from Mb0182 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0182 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTVVVEKTPT TLPQATPNGA APWHVRAGAF AIDVLPGLAV AATMALTALT VPPGSAWRWL
       61 CACLLGLTIL LLAVNRLLLP TITGWSLGRA LTGIRVVRRD GSAIGPWRLL VRDLAHLVDT
      121 LSLFVGWLWP LWDSRRRTFA DLLLRTEVRR VEPVQRPAVI RRLTAAVALA AAGACASATA
      181 VGAAVVYVNE WQTDHTRAQL ATRGPKLVVD VLSYDPETVQ RDFERARSLA TDRYRPQLSI
      241 QQDSVRESGP VRNQYWVTDS AVLSATPAQA TMLLFMQGER GTPPNQRYIS ATVRAIFQKS
      301 RGQWRLDDLA VVMKPRQPTG EK
//