LOCUS       CAB5247884.1             390 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            MCE-FAMILY LIPOPROTEIN LPRK (MCE-FAMILY LIPOPROTEIN MCE1E)
            protein.
ACCESSION   LT708304-183
PROTEIN_ID  CAB5247884.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lprK"
                     /locus_tag="BQ2027_MB0179"
                     /standard_name="mce1E"
                     /note="Mb0179, lprK, len: 390 aa. Equivalent to Rv0173,
                     len: 390 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 390 aa overlap). Possible lprK
                     (alternate gene name: mce1E), lipoprotein which belongs to
                     24-membered Mycobacterium tuberculosis Mce protein family
                     (see citations below for more information), highly similar
                     to Mycobacterium tuberculosis proteins
                     O07785|LPRL|Rv0593|MTCY19H5.29|mce2E (402 aa);
                     O53971|LPRM|Rv1970|MTV051.08|mce3E (377 aa); etc. Also
                     highly similar to others e.g. NP_302660.1|NC_002677
                     putative lipoprotein from Mycobacterium leprae (392 aa);
                     CAC12794.1|AL445327 putative secreted protein from
                     Streptomyces coelicolor (413 aa); etc. Contains PS00013
                     prokaryotic membrane lipoprotein lipid attachment site.
                     Protein product from Mb0179 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0179 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MMSVLARMRV MRHRAWQGLV LLVLALLLSS CGWRGISNVA IPGGPGTGPG SYTIYVQMPD
       61 TLAINGNSRV MVADVWVGSI RAIKLKNWVA TLTLSLKKDV TLPKNATAKI GQTSLLGSQH
      121 VELAAPPDPS PVPLKDGDTI PLKRSSAYPT TEQTLASIAT LLRGGGLVNL EGIQQEINAI
      181 VTGRADQIRA FLGKLDTFTD ELNQQRDDIT RAIDSTNRLL AYVGGRSEVL NRVLTDLPPL
      241 IKHFADKQEL LINASDAVGR LSQSADQYLS AARGDLHQDL QALQCPLKEL RRAAPYLVGA
      301 LKLILTQPFD VDTVPQLVRG DYMNLSLTLD LTYSAIDNAF LTGTGFSGAL RALEQSFGRD
      361 PETMIPDIRY TPNPNDAPGG PLVERGNRQC
//