LOCUS CAB5247884.1 390 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE MCE-FAMILY LIPOPROTEIN LPRK (MCE-FAMILY LIPOPROTEIN MCE1E) protein. ACCESSION LT708304-183 PROTEIN_ID CAB5247884.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lprK" /locus_tag="BQ2027_MB0179" /standard_name="mce1E" /note="Mb0179, lprK, len: 390 aa. Equivalent to Rv0173, len: 390 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 390 aa overlap). Possible lprK (alternate gene name: mce1E), lipoprotein which belongs to 24-membered Mycobacterium tuberculosis Mce protein family (see citations below for more information), highly similar to Mycobacterium tuberculosis proteins O07785|LPRL|Rv0593|MTCY19H5.29|mce2E (402 aa); O53971|LPRM|Rv1970|MTV051.08|mce3E (377 aa); etc. Also highly similar to others e.g. NP_302660.1|NC_002677 putative lipoprotein from Mycobacterium leprae (392 aa); CAC12794.1|AL445327 putative secreted protein from Streptomyces coelicolor (413 aa); etc. Contains PS00013 prokaryotic membrane lipoprotein lipid attachment site. Protein product from Mb0179 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0179 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /experiment="experimental evidence, no additional details recorded" BEGIN 1 MMSVLARMRV MRHRAWQGLV LLVLALLLSS CGWRGISNVA IPGGPGTGPG SYTIYVQMPD 61 TLAINGNSRV MVADVWVGSI RAIKLKNWVA TLTLSLKKDV TLPKNATAKI GQTSLLGSQH 121 VELAAPPDPS PVPLKDGDTI PLKRSSAYPT TEQTLASIAT LLRGGGLVNL EGIQQEINAI 181 VTGRADQIRA FLGKLDTFTD ELNQQRDDIT RAIDSTNRLL AYVGGRSEVL NRVLTDLPPL 241 IKHFADKQEL LINASDAVGR LSQSADQYLS AARGDLHQDL QALQCPLKEL RRAAPYLVGA 301 LKLILTQPFD VDTVPQLVRG DYMNLSLTLD LTYSAIDNAF LTGTGFSGAL RALEQSFGRD 361 PETMIPDIRY TPNPNDAPGG PLVERGNRQC //