LOCUS       CAB5247883.1             530 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 MCE-
            FAMILY PROTEIN MCE1D protein.
ACCESSION   LT708304-182
PROTEIN_ID  CAB5247883.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mce1D"
                     /locus_tag="BQ2027_MB0178"
                     /note="Mb0178, mce1D, len: 530 aa. Equivalent to Rv0172,
                     len: 530 aa, fromMycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 530 aa overlap). mce1D; belongs to
                     24-membered Mycobacterium tuberculosis Mce protein family
                     (see citations below for more information), highly similar
                     to Mycobacterium tuberculosis proteins
                     O07786|Rv0592|MTCY19H5.30c|mce2D (508 aa);
                     O53970|Rv1969|MTV051.07|mce3D (423 aa); etc. Also highly
                     similar to others e.g. NP_302659.1|NC_002677 putative
                     secreted protein from Mycobacterium leprae (531 aa);
                     CAC12795.1|AL445327 putative secreted protein from
                     Streptomyces coelicolor (337 aa); etc. Hydrophobic region
                     at N-terminus. Protein product from Mb0178 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb0178 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
BEGIN
        1 MSTIFDIRNL RLPQLSRASV VIGSLVVVLA LAAGIVGVRL YQKLTNNTVV AYFTQANALY
       61 VGDKVQIMGL PVGSIDKIEP AGDKMKVTFH YQNKYKVPAN ASAVILNPTL VASRNIQLEP
      121 PYRGGPVLAD NAVIPVERTQ VPTEWDELRD SVSHIIDELG PTPEQPKGPF GEVIEAFADG
      181 LAGKGKQINT TLNSLSQALN ALNEGRGDFF AVVRSLALFV NALHQDDQQF VALNKNLAEF
      241 TDRLTHSDAD LSNAIQQFDS LLAVARPFFA KNREVLTHDV NNLATVTTTL LQPDPLDGLE
      301 TVLHIFPTLA ANINQLYHPT HGGVVSLSAF TNFANPMEFI CSSIQAGSRL GYQESAELCA
      361 QYLAPVLDAI KFNYFPFGLN VASTASTLPK EIAYSEPRLQ PPNGYKDTTV PGIWVPDTPL
      421 SHRNTQPGWV VAPGMQGVQV GPITQGLLTP ESLAELMGGP DIAPPSSGLQ TPPGPPNAYD
      481 EYPVLPPIGL QAPQVPIPPP PPGPDVIPGP VPPTPAPVGA PLPAEAGGGQ
//