LOCUS       CAB5247879.1             289 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 conserved
            integral membrane protein yrbe1b protein.
ACCESSION   LT708304-178
PROTEIN_ID  CAB5247879.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="yrbE1B"
                     /locus_tag="BQ2027_MB0174"
                     /note="Mb0174, yrbE1B, len: 289 aa. Equivalent to Rv0168,
                     len: 289 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 289 aa overlap). yrbE1B, hypothetical
                     unknown integral membrane protein, part of mce1 operon and
                     member of YrbE family (see citations below for more
                     information), highly similar to Mycobacterium tuberculosis
                     proteins O07790|Rv0588|MTCY19H5.34|yrbE2B (295 aa);
                     O53966|Rv1965|MTV051.03|yrbE3B (271 aa); etc. Also highly
                     similar to conserved hypothetical integral membrane
                     proteins of the yrbEB type, e.g. NP_302655.1|NC_002677
                     conserved membrane protein from Mycobacterium leprae (289
                     aa); P45030|YRBE_HAEIN|HI1086 hypothetical protein from
                     Haemophilus influenzae (261 aa), FASTA scores: opt: 223,
                     E(): 7.6e-07, (23.7% identity in 257 aa overlap); etc.
                     Mb0174 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
BEGIN
        1 MSTAAVLRAR FPRAVANLRQ YGGAAARGLD EAGQLTWFAL TSIGQIAHAL RYYRKETLRL
       61 IAQIGMGTGA MAVVGGTVAI VGFVTLSGSS LVAIQGFASL GNIGVEAFTG FFAALINVRI
      121 AGPVVTGVAL AATVGAGATA ELGAMRISEE IDALEVMGIK SISFLASTRI MAGLVVIIPL
      181 YALAMIMSFL SPQITTTVLY GQSNGTYEHY FQTFLRPDDV FWSFLEALII TAIVMVSHCY
      241 YGYAAGGGPV GVGEAVGRSM RFSLVSVQVV VLFAALALYG VDPNFNLTV
//