LOCUS CAB5247871.1 502 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 pe family protein pe4 protein. ACCESSION LT708304-170 PROTEIN_ID CAB5247871.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PE4" /locus_tag="BQ2027_MB0165C" /note="Mb0165c, PE4, len: 502 aa. Equivalent to Rv0160c, len: 502 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 502 aa overlap). Member of the Mycobacterium tuberculosis PE family, similar to many other PE proteins e.g. Z92770|MTCI5_26c from M. tuberculosis (525 aa), FASTA scores: opt: 816, E(): 0, (41.4% identity in 367 aa overlap); C-terminal region of O06801|RV1768|MTCY28.34 from Mycobacterium tuberculosis (618 aa), FASTA scores: opt: 417, E(): 6.7e-18, (53.5% identity in 142 aa overlap). Also highly similar to downstream ORF MTV032_2. Mb0165c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MSHLVTAPDM LATAAAHVDE IASTLRAANA AAAGPTCNLL AAAGDEVSAA TAALFSAYGR 61 EYQAVVKQAA AFHSEFTRTL EAAGNAYAHA EAANAARVSH ALDTINAPIR TLLGRTPLSP 121 NGSSGAGGLP AIAQLAAESP ITALIMGGTN NPLPDPEYVT DINKAFIQTL FPGAVSQGLF 181 TPEQFWPVTP DLGNLTFNQS VTEGVALLNT TVNNQLALDN KVVAFGYSQS ATIINNYINS 241 LMAMGSPNPD DISFVMIGSG NNPVGGLLAR FPGFYIPFLD VPFNGATPAN SPYPTHIYTA 301 QYDGIAHAPQ FPLRILSDIN AFMGYFYVHN TYPELMATQV DNAVPLPTSP GYTGNTQYYM 361 FLTQDLPLLQ PIRDIPYAGP PIADLFQPQL RVLVDLGYAD YGPGGNYADI PTPAGLFSIP 421 NPFAVTYYLI KGSLQAPYGA IVEIGVEAGL IGPEWFPDSY PWVPSINPGL NFYFGQPQVT 481 LLSLMSGGLG NILHLIPPPV FT //