LOCUS       CAB5247871.1             502 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 pe
            family protein pe4 protein.
ACCESSION   LT708304-170
PROTEIN_ID  CAB5247871.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PE4"
                     /locus_tag="BQ2027_MB0165C"
                     /note="Mb0165c, PE4, len: 502 aa. Equivalent to Rv0160c,
                     len: 502 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 502 aa overlap). Member of the
                     Mycobacterium tuberculosis PE family, similar to many
                     other PE proteins e.g. Z92770|MTCI5_26c from M.
                     tuberculosis (525 aa), FASTA scores: opt: 816, E(): 0,
                     (41.4% identity in 367 aa overlap); C-terminal region of
                     O06801|RV1768|MTCY28.34 from Mycobacterium tuberculosis
                     (618 aa), FASTA scores: opt: 417, E(): 6.7e-18, (53.5%
                     identity in 142 aa overlap). Also highly similar to
                     downstream ORF MTV032_2. Mb0165c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MSHLVTAPDM LATAAAHVDE IASTLRAANA AAAGPTCNLL AAAGDEVSAA TAALFSAYGR
       61 EYQAVVKQAA AFHSEFTRTL EAAGNAYAHA EAANAARVSH ALDTINAPIR TLLGRTPLSP
      121 NGSSGAGGLP AIAQLAAESP ITALIMGGTN NPLPDPEYVT DINKAFIQTL FPGAVSQGLF
      181 TPEQFWPVTP DLGNLTFNQS VTEGVALLNT TVNNQLALDN KVVAFGYSQS ATIINNYINS
      241 LMAMGSPNPD DISFVMIGSG NNPVGGLLAR FPGFYIPFLD VPFNGATPAN SPYPTHIYTA
      301 QYDGIAHAPQ FPLRILSDIN AFMGYFYVHN TYPELMATQV DNAVPLPTSP GYTGNTQYYM
      361 FLTQDLPLLQ PIRDIPYAGP PIADLFQPQL RVLVDLGYAD YGPGGNYADI PTPAGLFSIP
      421 NPFAVTYYLI KGSLQAPYGA IVEIGVEAGL IGPEWFPDSY PWVPSINPGL NFYFGQPQVT
      481 LLSLMSGGLG NILHLIPPPV FT
//