LOCUS       CAB5247858.1             286 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE protein.
ACCESSION   LT708304-157
PROTEIN_ID  CAB5247858.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0153"
                     /note="Mb0153, -, len: 286 aa. Equivalent to Rv0148, len:
                     286 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 286 aa overlap). Probable short-chain
                     dehydrogenase (EC 1.-.-.-), similar to others, in
                     particular Estradiol 17 beta-dehydrogenases (EC 1.1.1.62),
                     e.g. DHB4_MOUSE|P51660 estradiol 17 beta-dehydrogenase 4
                     (735 aa), FASTA scores: opt: 952, E(): 0, (52.5% identity
                     in 276 aa overlap). Contains PS00061 Short-chain alcohol
                     dehydrogenase family signature. BELONGS TO THE SHORT-CHAIN
                     DEHYDROGENASES/REDUCTASES (SDR) FAMILY. Protein product
                     from Mb0153 detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb0153 found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MPGVQDRVIV VTGAGGGLGR EYALTLAGEG ASVVVNDLGG ARDGTGAGSA MADEVVAEIR
       61 DKGGRAVANY DSVATEDGAA NIIKTALDEF GAVHGVVSNA GILRDGTFHK MSFENWDAVL
      121 KVHLYGGYHV LRAAWPHFRE QSYGRVVVAT STSGLFGNFG QTNYGAAKLG LVGLINTLAL
      181 EGAKYNIHAN ALAPIAATRM TQDILPPEVL EKLTPEFVAP VVAYLCTEEC ADNASVYVVG
      241 GGKVQRVALF GNDGANFDKP PSVQDVAARW AEITDLSGAK IAGFKL
//