LOCUS       CAB5247849.1             340 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            oxidoreductase protein.
ACCESSION   LT708304-148
PROTEIN_ID  CAB5247849.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0144"
                     /note="Mb0144, -, len: 340 aa. Equivalent to Rv0139, len:
                     340 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 340 aa overlap). Putative
                     oxidoreductase (EC 1.-.-.-), similar to others e.g.
                     O34285|HPNA HPNA PROTEIN from Zymomonas mobilis (337 aa),
                     FASTA scores: opt: 507, E (): 5.8e-27, (31.1% identity in
                     328 aa overlap); TRE_STRGR|P29782 dtdp-glucose
                     4,6-dehydratase (328 aa), FASTA scores: opt: 254, E():
                     2.6e-10, (29.0% identity in 307 aa overlap). Protein
                     product from Mb0144 detected using SWATH mass
                     spectrometry. Mb0144 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MNAPKLVIGA NGFLGSHVTR QLVADCAPQK GEVRAMVRPA ANTRSIDDLP LTRFHGDVFD
       61 TATVAEAMAG CDDVYYCVVD TRAWLRDPSP LFRTNVAGLR NVLDVATDAS LRRFVFTSSY
      121 ATVGRRRGHV ATEEDRVDTR KVTPYVRSRV AAEDLVLQYA HDAGLPAVAM CVSTTYGGGD
      181 WGRTPHGAFI AGAVFGRLPF TMRGIRLEAV GVDDAARALI LAAERGHNGE RYLISERMMP
      241 LQEVVRIAAD EAGVPPPRWS ISVPVLYALG ALGSLRARLT GKDTELSLAS VRMMRSEADV
      301 DHGKAVRELG WQPRPVEESI REAARFWAAM RTVGKDPAAS
//