LOCUS       CAB5247834.1             455 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 maltokinase
            mak protein.
ACCESSION   LT708304-133
PROTEIN_ID  CAB5247834.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mak"
                     /locus_tag="BQ2027_MB0132"
                     /note="Mb0132, -, len: 455 aa. Equivalent to Rv0127, len:
                     455 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 455 aa overlap). Conserved hypothetical
                     protein, highly similar to various proteins e.g.
                     AJ0012|SCJ001205_4 hypothetical protein from Streptomyces
                     coelicolor A3(2) (464 aa), FASTA scores: opt: 412, E():
                     1.1e-19, (40.6% identity in 485 aa overlap);
                     AJ0012|SCJ001206_5 hypothetical protein from Streptomyces
                     coelicolor A3(2) (453 aa), FASTA scores: opt: 403, E():
                     4.3 e-19, (36.5% identity in 455 aa overlap). Protein
                     product from Mb0132 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0132 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MTRSDTLATK LPWSDWLPRQ RWYAGRNREL ATVKPGVVVA LRHNLDLVLV DVTYTDGATE
       61 RYQVLVGWDF EPASEYGTKA AIGVADDRTG FDALYDVAGP QFLLSLIVSS AVCGTSTGEV
      121 TFTREPDVEL PFAAQPRVCD AEQSNTSVIF DRRAILKVFR RVSSGINPDI ELNRVLTRAG
      181 NPHVARLLGA YQFGRPNRSP TDALAYALGM VTEYEANAAE GWAMATASVR DLFAEGDLYA
      241 HEVGGDFAGE SYRLGEAVAS VHATLADSLG TAQATFPVDR MLARLSSTVA VVPELREYAP
      301 TIEQQFQKLA AEAITVQRVH GDLHLGQVLR TPESWLLIDF EGEPGQPLDE RRAPDSPLRD
      361 VAGVLRSFEY AAYGPLVDQA TDKQLAARAR EWVERNRAAF CDGYAVASGI DPRDSALLLG
      421 AYELDKAVYE TGYETRHRPG WLPIPLRSIA RLTAS
//