LOCUS       CAB5247825.1             525 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            FATTY-ACID-COA LIGASE FADD7 (FATTY-ACID-COA SYNTHETASE)
            (FATTY-ACID-COA SYNTHASE) protein.
ACCESSION   LT708304-124
PROTEIN_ID  CAB5247825.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fadD7"
                     /locus_tag="BQ2027_MB0123"
                     /note="Mb0123, fadD7, len: 525 aa. Equivalent to Rv0119,
                     len: 525 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 525 aa overlap). Probable fadD7,
                     fatty-acid-CoA synthetase (EC 6.2.1.-), similar to
                     4-coumarate:CoA ligase of many organisms e.g.
                     U39405|PTU39405_1 4-coumarate:CoA ligase from Pinus
                     taedaxylem (537 aa), FASTA scores: opt: 483, E(): 8.3e-22,
                     (28.2% identity in 440 aa overlap). Contains PS00455
                     Putative AMP-binding domain signature. TBscore is 0.896.
                     Protein product from Mb0123 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry."
BEGIN
        1 MASDFGPRIA DLVEVAATRL PEAPALVVTA DRIAISHRDL ARLVDELAGQ LTRSGLLPGD
       61 RVALRMGSNA EFVVALLAAS RADLVVVPLD PALPITEQRV RSQAAGARVV LIDADGPHDR
      121 AEPTTRWWPL TVNVGGDSGP SGGTLSVHLD AATEPNPATS TPEGLRPDDA MIMFTGGTTG
      181 LPKMVPWTHA NIASSVRAII TGYRLSPRDA TVAVMPLYHG HGLIASLLAT LASGGAVSLP
      241 ARGRFSAHTF WDDIKAVGAT WYTAVPTIHQ ILLERSATEP SGRKPAALRF IRSCSAPLTA
      301 QAALALQTEF AAPVVCAFGM TEATHQVTTT QIEGIDQTET PVVSTGLVGR STGAQIRIVG
      361 SDGLPLPAGA VGEIWLRGTT VVRGYLGDPT ITAANFTDGW LRTGDLGSLS AAGDLSIRGR
      421 IKELINRGGE KISPERVEGV LASHPNVMEA AVFGVPHQLY GEAVAAVIVP RESAPPTREE
      481 LVQFCRERLA AFEIPASFQE ASGLPHTAKG SLDRRAVAER FGHSV
//