LOCUS CAB5247825.1 525 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE FATTY-ACID-COA LIGASE FADD7 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-COA SYNTHASE) protein. ACCESSION LT708304-124 PROTEIN_ID CAB5247825.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="fadD7" /locus_tag="BQ2027_MB0123" /note="Mb0123, fadD7, len: 525 aa. Equivalent to Rv0119, len: 525 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 525 aa overlap). Probable fadD7, fatty-acid-CoA synthetase (EC 6.2.1.-), similar to 4-coumarate:CoA ligase of many organisms e.g. U39405|PTU39405_1 4-coumarate:CoA ligase from Pinus taedaxylem (537 aa), FASTA scores: opt: 483, E(): 8.3e-22, (28.2% identity in 440 aa overlap). Contains PS00455 Putative AMP-binding domain signature. TBscore is 0.896. Protein product from Mb0123 detected using shotgun mass spectrometry and SWATH mass spectrometry." BEGIN 1 MASDFGPRIA DLVEVAATRL PEAPALVVTA DRIAISHRDL ARLVDELAGQ LTRSGLLPGD 61 RVALRMGSNA EFVVALLAAS RADLVVVPLD PALPITEQRV RSQAAGARVV LIDADGPHDR 121 AEPTTRWWPL TVNVGGDSGP SGGTLSVHLD AATEPNPATS TPEGLRPDDA MIMFTGGTTG 181 LPKMVPWTHA NIASSVRAII TGYRLSPRDA TVAVMPLYHG HGLIASLLAT LASGGAVSLP 241 ARGRFSAHTF WDDIKAVGAT WYTAVPTIHQ ILLERSATEP SGRKPAALRF IRSCSAPLTA 301 QAALALQTEF AAPVVCAFGM TEATHQVTTT QIEGIDQTET PVVSTGLVGR STGAQIRIVG 361 SDGLPLPAGA VGEIWLRGTT VVRGYLGDPT ITAANFTDGW LRTGDLGSLS AAGDLSIRGR 421 IKELINRGGE KISPERVEGV LASHPNVMEA AVFGVPHQLY GEAVAAVIVP RESAPPTREE 481 LVQFCRERLA AFEIPASFQE ASGLPHTAKG SLDRRAVAER FGHSV //