LOCUS       CAB5247824.1             582 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            OXALYL-COA DECARBOXYLASE OXCA protein.
ACCESSION   LT708304-123
PROTEIN_ID  CAB5247824.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="oxcA"
                     /locus_tag="BQ2027_MB0122C"
                     /note="Mb0122c, oxcA, len: 582 aa. Equivalent to Rv0118c,
                     len: 582 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 582 aa overlap). Probable oxcA,
                     oxalyl-CoA decarboxylase (EC 4.1.1.8), highly similar to
                     many e.g. P78093|OXC_ECOLI|7449483|B65011|YFDU|B2373|Z3637
                     |ECS325 PROBABLE OXALYL-CoA DECARBOXYLASE from Escherichia
                     coli (564 aa); M77128|OXAOXA_1 oxalyl-CoA decarboxylase
                     from Oxalobacter formigenes (568 aa), FASTA scores: opt:
                     2124, E():0, (55.6% identity in 568 aa overlap). Also
                     similar to mycobacterial IlvB proteins e.g. MLCB1788.46c
                     unknown TPP-requiring enzyme from Mycobacterium leprae
                     (548 aa); and AL0086|MLCB1788_19 from Mycobacterium leprae
                     (548 aa), FASTA scores: opt: 831, E(): 0, (33.9% identity
                     in 567 aa overlap). Protein product from Mb0122c detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry."
BEGIN
        1 MTTRSASPCT VLTDGCHLVV DALKANDVDT IYGVVGIPIT DLARAAQASG IRYIGFRHEA
       61 SAGNAAAAAG FLTARPGVCL TTSGPGFLNG LPALANATTN CFPMIQISGS SSRPMVDLQR
      121 GDYQDLDQLN AARPFVKAAY RIGQVQDIGR GVARAIRTAT SGRPGGVYLD IPGDVLGQAV
      181 EASAASGAIW RPVDPAPRLL PAPEAIDRAL DVLAQAQRPL LVLGKGAAYA QADNVIREFV
      241 EHTGIPFLPM SMAKGLLPDS HPQSAAAARS LAMARADVVL LVGARLNWLL GNGESPQWSA
      301 DAKFIQVDIE ASEFDSNRPI VAPLTGDIGS VMSALLEAAA DRSSVASAAW TGELADRKAR
      361 NSAKMRRRLA DDHHPMRFYN ALGAIRSVLQ RNPDVYVVNE GANALDLARN IIDMHLPRHR
      421 LDSGTWGVMG IGMGYAIAAA VETGRPVVAI EGDSAFGFSG MEFETICRYR LPVTVVILNN
      481 GGVYRGDEAT IFRSAAPVWR HDPAPTVLNA HARHELIAEA FGGKGYHVST PTELESALTD
      541 ALASNGPSLI DCELDPADGV ESGHLAKLNT TSAATPAISG DG
//