LOCUS       CAB5247821.1             305 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            d-alpha-d-heptose-7-phosphate kinase hdda protein.
ACCESSION   LT708304-120
PROTEIN_ID  CAB5247821.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="hdda"
                     /locus_tag="BQ2027_MB0119"
                     /note="Mb0119, -, len: 305 aa. Equivalent to Rv0115, len:
                     386 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (98.5% identity in 275 aa overlap). Possible sugar kinase
                     (EC 2.-.-.-), similar to several hypothetical proteins and
                     sugar kinases e.g. AAK27850.1|AF324836_3
                     D-glycero-D-manno-heptose 7-phosphate kinase from
                     Aneurinibacillus thermoaerophilus (341 aa);
                     AAK80995.1|AE007802_11 Sugar kinase from Clostridium
                     acetobutylicum (364 aa). REMARK-M.bovis-M.tuberculosis: In
                     Mycobacterium bovis, a single base insertion (*-c) leads
                     to shorter product with a different COOH part compared to
                     its homolog in Mycobacterium tuberculosis strain H37Rv."
BEGIN
        1 MRSPFARRTA TEPARPRSTI WRLSKKTLPL HVAVYRRVIA EFNGGTPFPL QLATQVDAPP
       61 GSGLGSSSAL VVAMLLTTCA LIGSSPGPYE LARLAWEIER VDLGMAGGWQ DHYAAAFGGF
      121 NFMESRPNGE VVVNPLRIRR EVIAELEASL LLYFGGVSRL SSEVIADQQR NVVERDADAL
      181 AATHSICAEA LEMKDLLVVG DIPGFADSLL RGWQAKKRTS TRISNPAIEH AYQVAQSSGM
      241 VAGKVSGAGG GGFLMMIVDP RRRIEVARSL ERECGGSVAP CLFTKGGAVT WHIPESTAPR
      301 KAWSC
//