LOCUS       CAB5247820.1             190 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            d-alpha,beta-d-heptose-1,7-biphosphate phosphatase gmhb
            (d-glycero-d-manno-heptose 7-phosphate kinase) protein.
ACCESSION   LT708304-119
PROTEIN_ID  CAB5247820.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="gmhb"
                     /locus_tag="BQ2027_MB0118"
                     /note="Mb0118, -, len: 190 aa. Equivalent to Rv0114, len:
                     190 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.5% identity in 190 aa overlap). Possible dehydratase
                     (EC 4.-.-.-), similar to several hypothetical proteins and
                     to HIS7_ECOLI|P06987 imidazoleglycerol-phosphate
                     dehydratase (355 aa), FASTA scores: opt: 250, E():
                     3.6e-11, (34.0 % identity in 141 aa overlap). Mb0118 found
                     to be expressed during exponential growth in Sauton's
                     minimal media by RNA-sequencing (TPM > 20)."
BEGIN
        1 MVAERAGHQW CLFLDRDGVI NRQVVGDYVR NWRQFEWLPG AARALKKLRA WAPYIVVVTN
       61 QQGVGAGLMS AVDVMVIHRH LQMQLASDGV LIDGFQVCPH HRSQRCGCRK PRPGLVLDWL
      121 RRHPDSEPLL SIVVGDSLSD LELAHNVAAA AGACASVQIG GASSGGVADA SFDSLWEFAV
      181 AVGHARGERG
//