LOCUS CAB5247817.1 685 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE TRANSMEMBRANE ACYLTRANSFERASE protein. ACCESSION LT708304-116 PROTEIN_ID CAB5247817.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0115" /note="Mb0115, -, len: 685 aa. Equivalent to Rv0111, len: 685 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 685 aa overlap). Possible transmembrane acyltransferase (EC 2.3.1.-), equivalent to AA22904.1|AL035300 putative acyltransferase from Mycobacterium leprae (696 aa). Also similar to others e.g. C69975 acyltransferase homolog yrhL from Bacillus subtilis (634 aa), FASTA scores: opt: 520, E(): 4e-22, (36.4% identity in 382 aa overlap). Very similar to Mycobacterium tuberculosis proteins Rv0228, Rv1254, Rv1565c, etc. Mb0115 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." BEGIN 1 MPARSVPRPR WVAPVRRVGR LAVWDRPERR SGIPALDGLR AIAVALVLAS HGGIPGMGGG 61 FIGVDAFFVL SGFLITSLLL DELGRTGRID LSGFWIRRAR RLLPALVLMV LTVSAARALF 121 PDQALTGLRS DAIAAFLWTA NWRFVAQNTD YFTQGAPPSP LQHTWSLGVE EQYYVVWPLL 181 LIGATLLLAA RARRRCRRAT VGGVRFAAFL IASLGTMASA TAAVAFTSAA TRDRIYFGTD 241 TRAQALLIGS AAAALLVRDW PSLNRGWCLI RTRWGRRIAR LLPFVGLAGL AVTTHVATGS 301 VGEFRHGLLI VVAGAAVIVV ASVAMEQRGA VARILAWRPL VWLGTISYGV YLWHWPIFLA 361 LNGQRTGWSG PALFAARCAA TVVLAGASWW LIEQPIRRWR PARVPLLPLA AATVASAAAV 421 TMLVVPVGAG PGLREIGLPP GVSAVAAVSP SPPEASQPAP GPRDPNRPFT VSVFGDSIGW 481 TLMHYLPPTP GFRFIDHTVI GCSLVRGTPY RYIGQTLEQR AECDGWPARW SAQVNRDQPD 541 VALLIVGRWE TVDRVNEGRW THIGDPTFDA YLNAELQRAL SIVGSTGVRV MVTTVPYSRG 601 GEKPDGRLYP EDQPERVNKW NAMLHNAISQ HSNVGMIDLN KKLCPDGVYT AKVDGIKVRS 661 DGVHLTQEGV KWLIPWLEDS VRVAS //