LOCUS       CAB5247817.1             685 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            TRANSMEMBRANE ACYLTRANSFERASE protein.
ACCESSION   LT708304-116
PROTEIN_ID  CAB5247817.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0115"
                     /note="Mb0115, -, len: 685 aa. Equivalent to Rv0111, len:
                     685 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 685 aa overlap). Possible
                     transmembrane acyltransferase (EC 2.3.1.-), equivalent to
                     AA22904.1|AL035300 putative acyltransferase from
                     Mycobacterium leprae (696 aa). Also similar to others e.g.
                     C69975 acyltransferase homolog yrhL from Bacillus subtilis
                     (634 aa), FASTA scores: opt: 520, E(): 4e-22, (36.4%
                     identity in 382 aa overlap). Very similar to Mycobacterium
                     tuberculosis proteins Rv0228, Rv1254, Rv1565c, etc. Mb0115
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
BEGIN
        1 MPARSVPRPR WVAPVRRVGR LAVWDRPERR SGIPALDGLR AIAVALVLAS HGGIPGMGGG
       61 FIGVDAFFVL SGFLITSLLL DELGRTGRID LSGFWIRRAR RLLPALVLMV LTVSAARALF
      121 PDQALTGLRS DAIAAFLWTA NWRFVAQNTD YFTQGAPPSP LQHTWSLGVE EQYYVVWPLL
      181 LIGATLLLAA RARRRCRRAT VGGVRFAAFL IASLGTMASA TAAVAFTSAA TRDRIYFGTD
      241 TRAQALLIGS AAAALLVRDW PSLNRGWCLI RTRWGRRIAR LLPFVGLAGL AVTTHVATGS
      301 VGEFRHGLLI VVAGAAVIVV ASVAMEQRGA VARILAWRPL VWLGTISYGV YLWHWPIFLA
      361 LNGQRTGWSG PALFAARCAA TVVLAGASWW LIEQPIRRWR PARVPLLPLA AATVASAAAV
      421 TMLVVPVGAG PGLREIGLPP GVSAVAAVSP SPPEASQPAP GPRDPNRPFT VSVFGDSIGW
      481 TLMHYLPPTP GFRFIDHTVI GCSLVRGTPY RYIGQTLEQR AECDGWPARW SAQVNRDQPD
      541 VALLIVGRWE TVDRVNEGRW THIGDPTFDA YLNAELQRAL SIVGSTGVRV MVTTVPYSRG
      601 GEKPDGRLYP EDQPERVNKW NAMLHNAISQ HSNVGMIDLN KKLCPDGVYT AKVDGIKVRS
      661 DGVHLTQEGV KWLIPWLEDS VRVAS
//