LOCUS       CAB5247815.1             496 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 pe-
            pgrs family protein pe_pgrs1 protein.
ACCESSION   LT708304-114
PROTEIN_ID  CAB5247815.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PE_PGRS1"
                     /locus_tag="BQ2027_MB0113"
                     /note="Mb0113, PE_PGRS1, len: 496 aa. Equivalent to
                     Rv0109, len: 496 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (99.8% identity in 496 aa overlap). Member
                     of the Mycobacterium tuberculosis PE family, PGRS
                     subfamily of gly-rich proteins, highly similar to many
                     e.g. Q50615|Y0DP_MYCTU HYPOTHETICAL GLYCINE-RICH 40.8 KD
                     PROTEIN from Mycobacterium tuberculosis (498 aa), FASTA
                     scores: opt: 1772, E(): 0, (57.3% identity in 513 aa
                     overlap); etc. Mb0113 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MSLLITSPAT VAAAATHLAG IGSALSTANA AAAAPTTALS VAGADEVSVL IAALFEAYAQ
       61 EYQALSAQAL AFHDQFVQAL NMGAVCYAAA ETANATPLQA LQTVQQNVLT VVNAPTQALL
      121 GRPIIGNGAN GLPNTGQDGG PGGLLFGNGG NGGSGGVDQA GGNGGAAGLI GNGGSGGVGG
      181 PGIAGSAGGA GGAGGLLFGN GGPGGAGGIG TTGDGGPGGA GGNAIGLFGS GGTGGMGGVG
      241 GMGGVGNGGN AGNGGTAGLF GHGGAGGAGG IGSADGGLGG GGGNGRFMGN GGVGGAGGYG
      301 ASGDGGNAGN GGLGGVFGDG GAGGTGGLGD VNGGLAGIGG NAGFVGNGGA GGNGQLGSGA
      361 VSSAGGMGGN GGLVFGNGGP GGLGGPGTSA GNGGMGGNAV GLFGQGGAGG AGGSGFGAGI
      421 PGGRGGDGGS GGLIGDGGTG GGAGAGDAAA SAGGNGGNAR LIGNGGDGGP GMFGGPGGAG
      481 GSGGTIFGFA GTPGPS
//