LOCUS       CAB5247812.1             398 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Metal
            chaperone, involved in Zn homeostasis protein.
ACCESSION   LT708304-111
PROTEIN_ID  CAB5247812.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0109"
                     /note="Mb0109, -, len: 398 aa. Equivalent to Rv0106, len:
                     398 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 398 aa overlap). Conserved
                     hypothetical protein, similar to others e.g.
                     AL049841|SCE9_33 from Streptomyces coelicolor (370 aa),
                     FASTA scores: opt: 282, E(): 2.5e-11, (32.0% identity in
                     381 aa overlap); etc. Some similarity to P94400 HOMOLOGUE
                     TO NITRILE HYDRATASE REGION from Bacillus subtilis (397
                     aa), FASTA scores: opt: 226, E(): 5.4e-08, (26.4% identity
                     in 405 aa overlap). Also similar to COBW_PSEDE|P29937
                     FASTA score: (25.3% identity in 186 aa overlap); and
                     P47K_PSECL|P31521 47 kd protein (p47k) (419 aa), FASTA
                     score: (25.9% identity in 401 aa overlap). Protein product
                     from Mb0109 detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb0109 found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MRTPVILVAG QDHTDEVTGA LLRRTGTVVV EHRFDGHVVR RMTATLSRGE LITTEDALEF
       61 AHGCVSCTIR DDLLVLLRRL HRRDNVGRIV VHLAPWLEPQ PICWAIDHVR VCVGHGYPDG
      121 PAALDVRVAA VVTCVDCVRW LPQSLGEDEL PDGRTVAQVT VGQAEFADLL VLTHPEPVAV
      181 AVLRRLAPRA RITGGVDRVE LALAHLDDNS RRGRTDTPHT PLLAGLPPLA ADGEVAIVEF
      241 SARRPFHPQR LHAAVDLLLD GVVRTRGRLW LANRPDQVMW LESAGGGLRV ASAGKWLAAM
      301 AASEVAYVDL ERRLFADLMW VYPFGDRHTA MTVLVCGADP TDIVNALNAA LLSDDEMASP
      361 QRWQSYVDPF GDWHDDPCHE MPDAAGEFSA HRNSGESR
//