LOCUS CAB5247812.1 398 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Metal chaperone, involved in Zn homeostasis protein. ACCESSION LT708304-111 PROTEIN_ID CAB5247812.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0109" /note="Mb0109, -, len: 398 aa. Equivalent to Rv0106, len: 398 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 398 aa overlap). Conserved hypothetical protein, similar to others e.g. AL049841|SCE9_33 from Streptomyces coelicolor (370 aa), FASTA scores: opt: 282, E(): 2.5e-11, (32.0% identity in 381 aa overlap); etc. Some similarity to P94400 HOMOLOGUE TO NITRILE HYDRATASE REGION from Bacillus subtilis (397 aa), FASTA scores: opt: 226, E(): 5.4e-08, (26.4% identity in 405 aa overlap). Also similar to COBW_PSEDE|P29937 FASTA score: (25.3% identity in 186 aa overlap); and P47K_PSECL|P31521 47 kd protein (p47k) (419 aa), FASTA score: (25.9% identity in 401 aa overlap). Protein product from Mb0109 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0109 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MRTPVILVAG QDHTDEVTGA LLRRTGTVVV EHRFDGHVVR RMTATLSRGE LITTEDALEF 61 AHGCVSCTIR DDLLVLLRRL HRRDNVGRIV VHLAPWLEPQ PICWAIDHVR VCVGHGYPDG 121 PAALDVRVAA VVTCVDCVRW LPQSLGEDEL PDGRTVAQVT VGQAEFADLL VLTHPEPVAV 181 AVLRRLAPRA RITGGVDRVE LALAHLDDNS RRGRTDTPHT PLLAGLPPLA ADGEVAIVEF 241 SARRPFHPQR LHAAVDLLLD GVVRTRGRLW LANRPDQVMW LESAGGGLRV ASAGKWLAAM 301 AASEVAYVDL ERRLFADLMW VYPFGDRHTA MTVLVCGADP TDIVNALNAA LLSDDEMASP 361 QRWQSYVDPF GDWHDDPCHE MPDAAGEFSA HRNSGESR //