LOCUS       CAB5247808.1             661 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED INTEGRAL MEMBRANE PROTEIN protein.
ACCESSION   LT708304-107
PROTEIN_ID  CAB5247808.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0105"
                     /note="Mb0105, -, len: 661 aa. Equivalent to Rv0102, len:
                     661 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 661 aa overlap). Probable conserved
                     integral membrane protein, highly similar to
                     P53525|Y102_MYCLE|ML1998|NP_302349.1|NC_002677 possible
                     membrane protein from Mycobacterium leprae (659 aa), FASTA
                     scores: opt: 3107, E(): 0, (70.2% identity in 662 aa
                     overlap). Also similar to others e.g. CAC01497.1|AL391017
                     putative integral membrane protein from Streptomyces
                     coelicolor (316 aa); etc. Contains PS00343 Gram-positive
                     cocci surface proteins 'anchoring' hexapeptide. Protein
                     product from Mb0105 detected using SWATH mass
                     spectrometry. Mb0105 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MGTHGATKSA TSAVPTPRSN SMAMVRLAIG LLGVCAVVAA FGLVSGARRY AEAGNPYPGA
       61 FVSVAEPVGF FAASLAGALC LGALIHVVMT AKPEPDGLID AAAFRIHLLA ERVSGLWLGL
      121 AATMVVIQAA HDTGVGPARL LASGALSDSV AASEMARGWI VAAICALVVA TALRLYTRWL
      181 GHVVLLVPTV LAVVATAVTG NPGQGPDHDY ATSAAIVFAV AFATLTGLKI AAALAGTTPS
      241 RAVLVTQVTC GALALAYGAM LLYLFIPGWA VDSDFARLGL LAGVILTSVW LFDCWRLLVR
      301 PPHAGRRRGG GSGAALAMMA AMASIAAMAV MTAPRFLTHA FTAWDVFLGY ELPQPPTIAR
      361 VLTVWRFDSL IGAAGVVLAI GYAAGFAALR RRGNSWPVGR LIAWLTGCAA LVFTSGSGVR
      421 AYGSAMFSVH MAEHMTLNMF IPVLLVLGGP VTLALRVLPV TGDGRPPGAR EWLTWLLHSR
      481 VTTFLSHPIT AFVLFVASPY IVYFTPLFDT FVRYHWGHEF MAIHFLVVGY LFYWAIIGID
      541 PGPRRLPYPG RIGLLFAVMP FHAFFGIALM TMSSTVGATF YRSVNLPWLS SIIADQHLGG
      601 GIAWSLTELP VIMVIVALVT QWARQDRRVA SREDRHADSD YADDELEAYN AMLRELSRMR
      661 R
//