LOCUS CAB5247808.1 661 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN protein. ACCESSION LT708304-107 PROTEIN_ID CAB5247808.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0105" /note="Mb0105, -, len: 661 aa. Equivalent to Rv0102, len: 661 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 661 aa overlap). Probable conserved integral membrane protein, highly similar to P53525|Y102_MYCLE|ML1998|NP_302349.1|NC_002677 possible membrane protein from Mycobacterium leprae (659 aa), FASTA scores: opt: 3107, E(): 0, (70.2% identity in 662 aa overlap). Also similar to others e.g. CAC01497.1|AL391017 putative integral membrane protein from Streptomyces coelicolor (316 aa); etc. Contains PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. Protein product from Mb0105 detected using SWATH mass spectrometry. Mb0105 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MGTHGATKSA TSAVPTPRSN SMAMVRLAIG LLGVCAVVAA FGLVSGARRY AEAGNPYPGA 61 FVSVAEPVGF FAASLAGALC LGALIHVVMT AKPEPDGLID AAAFRIHLLA ERVSGLWLGL 121 AATMVVIQAA HDTGVGPARL LASGALSDSV AASEMARGWI VAAICALVVA TALRLYTRWL 181 GHVVLLVPTV LAVVATAVTG NPGQGPDHDY ATSAAIVFAV AFATLTGLKI AAALAGTTPS 241 RAVLVTQVTC GALALAYGAM LLYLFIPGWA VDSDFARLGL LAGVILTSVW LFDCWRLLVR 301 PPHAGRRRGG GSGAALAMMA AMASIAAMAV MTAPRFLTHA FTAWDVFLGY ELPQPPTIAR 361 VLTVWRFDSL IGAAGVVLAI GYAAGFAALR RRGNSWPVGR LIAWLTGCAA LVFTSGSGVR 421 AYGSAMFSVH MAEHMTLNMF IPVLLVLGGP VTLALRVLPV TGDGRPPGAR EWLTWLLHSR 481 VTTFLSHPIT AFVLFVASPY IVYFTPLFDT FVRYHWGHEF MAIHFLVVGY LFYWAIIGID 541 PGPRRLPYPG RIGLLFAVMP FHAFFGIALM TMSSTVGATF YRSVNLPWLS SIIADQHLGG 601 GIAWSLTELP VIMVIVALVT QWARQDRRVA SREDRHADSD YADDELEAYN AMLRELSRMR 661 R //