LOCUS       CAB5247803.1             289 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            OXIDOREDUCTASE protein.
ACCESSION   LT708304-102
PROTEIN_ID  CAB5247803.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0100"
                     /note="Mb0100, -, len: 289 aa. Equivalent to Rv0097, len:
                     289 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 289 aa overlap). Possible
                     oxidoreductase (EC 1.-.-.-), equivalent to
                     NP_302343.1|NC_002677 putative oxidoreductase from
                     Mycobacterium leprae (289 aa). Also highly similar to
                     BAB69377.1|AB070955 putative oxidoreductase from
                     Streptomyces avermitilis (296 aa); and weakly similar to
                     others e.g. NP_518867.1|NC_003295 PUTATIVE
                     ALPHA-KETOGLUTARATE-DEPENDENT TAURINE DIOXYGENASE
                     OXIDOREDUCTASE PROTEIN from Ralstonia solanacearum (301
                     aa); NP_286110.1|NC_002655 taurine dioxygenase
                     (2-oxoglutarate-dependent) from Escherichia coli strain
                     O157:H7 (283 aa); NP_252624.1|NC_002516 taurine
                     dioxygenase from Pseudomonas aeruginosa (277 aa);
                     ECAE00014310 (283 aa), FASTA scores: opt: 304, E():
                     2.6e-13, (27.8% identity in 288 aa overlap);
                     TFDA_ALCEU|P10088 2,4-dichlorophenoxyacetate monooxygenase
                     from A. eutropha (287 aa), FASTA scores: opt: 188, E():
                     3.5e-06, (26.6% identity in 188 aa overlap); etc. Contains
                     PS00077 Cytochrome c oxidase subunit I, copper B binding
                     region signature. Protein product from Mb0100 detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb0100 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTLKVKGEGL GAQVTGVDPK NLDDITTDEI RDIVYTNKLV VLKDVHPSPR EFIKLGRIIG
       61 QIVPYYEPMY HHEDHPEIFV SSTEEGQGVP KTGAFWHIDY MFMPEPFAFS MVLPLAVPGH
      121 DRGTYFIDLA RVWQSLPAAK RDPARGTVST HDPRRHIKIR PSDVYRPIGE VWDEINRTTP
      181 PIKWPTVIRH PKTGQEILYI CATGTTKIED KDGNPVDPEV LQELMAATGQ LDPEYQSPFI
      241 HTQHYQVGDI ILWDNRVLMH RAKHGSAAGT LTTYRLTMLD GLKTPGYAA
//