LOCUS CAB5247803.1 289 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE OXIDOREDUCTASE protein. ACCESSION LT708304-102 PROTEIN_ID CAB5247803.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0100" /note="Mb0100, -, len: 289 aa. Equivalent to Rv0097, len: 289 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 289 aa overlap). Possible oxidoreductase (EC 1.-.-.-), equivalent to NP_302343.1|NC_002677 putative oxidoreductase from Mycobacterium leprae (289 aa). Also highly similar to BAB69377.1|AB070955 putative oxidoreductase from Streptomyces avermitilis (296 aa); and weakly similar to others e.g. NP_518867.1|NC_003295 PUTATIVE ALPHA-KETOGLUTARATE-DEPENDENT TAURINE DIOXYGENASE OXIDOREDUCTASE PROTEIN from Ralstonia solanacearum (301 aa); NP_286110.1|NC_002655 taurine dioxygenase (2-oxoglutarate-dependent) from Escherichia coli strain O157:H7 (283 aa); NP_252624.1|NC_002516 taurine dioxygenase from Pseudomonas aeruginosa (277 aa); ECAE00014310 (283 aa), FASTA scores: opt: 304, E(): 2.6e-13, (27.8% identity in 288 aa overlap); TFDA_ALCEU|P10088 2,4-dichlorophenoxyacetate monooxygenase from A. eutropha (287 aa), FASTA scores: opt: 188, E(): 3.5e-06, (26.6% identity in 188 aa overlap); etc. Contains PS00077 Cytochrome c oxidase subunit I, copper B binding region signature. Protein product from Mb0100 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0100 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /experiment="experimental evidence, no additional details recorded" BEGIN 1 MTLKVKGEGL GAQVTGVDPK NLDDITTDEI RDIVYTNKLV VLKDVHPSPR EFIKLGRIIG 61 QIVPYYEPMY HHEDHPEIFV SSTEEGQGVP KTGAFWHIDY MFMPEPFAFS MVLPLAVPGH 121 DRGTYFIDLA RVWQSLPAAK RDPARGTVST HDPRRHIKIR PSDVYRPIGE VWDEINRTTP 181 PIKWPTVIRH PKTGQEILYI CATGTTKIED KDGNPVDPEV LQELMAATGQ LDPEYQSPFI 241 HTQHYQVGDI ILWDNRVLMH RAKHGSAAGT LTTYRLTMLD GLKTPGYAA //