LOCUS       CAB5247802.1             463 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ppe
            family protein ppe1 protein.
ACCESSION   LT708304-101
PROTEIN_ID  CAB5247802.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PPE1"
                     /locus_tag="BQ2027_MB0099"
                     /note="Mb0099, PPE1, len: 463 aa. Equivalent to Rv0096,
                     len: 463 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 463 aa overlap). Member of the
                     Mycobacterium tuberculosis PPE family, similar to many
                     e.g. Z46257|MLACEA_3 aceA gene for isocitrate L from M.
                     leprae (438 aa), FASTA scores: opt: 1207, E(): 0, (55.3%
                     identity in 380 aa overlap). Also similar to
                     Z97559|MTCY261_19 from Mycobacterium tuberculosis (473
                     aa), FASTA score: (40.2% identity in 478 aa overlap);
                     YHS6_MYCTU|P42611 hypothetical 50.6 kd protein (517 aa),
                     FASTA scores: opt: 365, E(): 4.6e-12, (37.6% identity in
                     178 aa overlap). Also similar to MTCY274.23c from M.
                     tuberculosis FASTA score: (31.1% identity in 383 overlap).
                     Some similarity also to MTCY31.06c and MTCY48.17 and other
                     mycobacterial PPE family proteins."
BEGIN
        1 MAIPPEVHSG LLSAGCGPGS LLVAAQQWQE LSDQYALACA ELGQLLGEVQ ASSWQGTAAT
       61 QYVAAHGPYL AWLEQTAINS AVTAAQHVAA AAAYCSALAA MPTPAELAAN HAIHGVLIAT
      121 NFFGINTVPI ALNEADYVRM WLQAADTMAA YQAVADAATV AVPSTQPAPP IRAPGGDAAD
      181 TWLDVLSSIG QLIRDILDFI ANPYKYFLEF FEQFGFSPAV TVVLALVALQ LYDFLWYPYY
      241 ASYGLLLLPF FTPTLSALTA LSALIHLLNL PPAGLLPIAA ALGPGDQWGA NLAVAVTPAT
      301 AAVPGGSPPT SNPAPAAPSS NSVGSASAAP GISYAVPGLA PPGVSSGPKA GTKSPDTAAD
      361 TLATAGAARP GLARAHRRKR SESGVGIRGY RDEFLDATAT VDAATDVPAP ANAAGSQGAG
      421 TLGFAGTAPT TSGAAAGMVQ LSSHSTSTTV PLLPTTWTTD AEQ
//