LOCUS CAB5247801.1 260 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED HYPOTHETICAL PROTEIN protein. ACCESSION LT708304-100 PROTEIN_ID CAB5247801.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0098C" /note="Mb0098c, -, len: 260 aa. Equivalent to Rv1588 and Rv0095c, len: 222 aa and 136 aa, from Mycobacterium tuberculosis strain H37Rv, (98.2% identity in 222 aa overlap and 92.5% identity in 134 aa overlap). Member of 13E12 repeat, also partially similar to AF0418|AF041819_8 from Mycobacterium bovis BCG (222 aa), FASTA score: (89.6% identity in 96 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, Rv0095c and Rv1588 exist as separate genes in their respective positions. In Mycobacterium bovis, a 73 bp substitution leads to a single combined gene. Mb0098c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MRYLPVSTRR IWVNPLCHFS FTVISGALFV SARRYDSNML ANSREELVEV FDALDAELDR 61 LDEVSFEVLT TPERLRSLER LECLVRRLPA VGHTLINQLD TQASEEELGG TLCCALANRL 121 RITKPDAALR IADAADLGPR RALTGEPLAP QLTATATAQR QGLIGEAHIK VIRALFRPPA 181 RRGGCVHPPG RRSRPGRQSR SISSRRAGPL RPAGHGLATP RRRPHRHRTR PQTRHHPEQP 241 AIRRHVTAKW LPDPPSAGHL //