LOCUS       CAB5247779.1             390 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            AMINOTRANSFERASE protein.
ACCESSION   LT708304-78
PROTEIN_ID  CAB5247779.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0077"
                     /note="Mb0077, -, len: 390 aa. Equivalent to Rv0075, len:
                     390 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 390 aa overlap). Probable
                     aminotransferase (EC 2.6.1.-), similar to many CLASS-II
                     PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASES (MALY/PATB
                     SUBFAMILY) e.g. NP_302217.1|NC_002677 aminotransferase
                     from Mycobacterium leprae (402 aa); PATB_BACSU|Q08432
                     putative aminotransferase b from Bacillus subtilis (387
                     aa), FASTA scores: opt: 684, E(): 5.4e-33, (31.3% identity
                     in 384 aa overlap); etc. Also similar to several
                     cystathionine beta-lyase (beta C-S lyase) e.g.
                     AAK69425.1|AF276227_1|AF276227 from Corynebacterium
                     glutamicum (368 aa); etc. Also similar to other proteins
                     from Mycobacterium tuberculosis e.g. Rv2294, Rv0858c, etc.
                     Protein product from Mb0077 detected using SWATH mass
                     spectrometry. Mb0077 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MQDSIFNLLT EEQLRGRNTL KWNYFGPDVV PLWLAEMDFP TAPAVLDGVR ACVDNEEFGY
       61 PPLGEDSLPR ATADWCRQRY GWCPRPDWVR VVPDVLKGME VVVEFLTRPE SPVALPVPAY
      121 MPFFDVLHVT GRQRVEVPMV QQDSGRYLLD LDALQAAFVR GAGSVIICNP NNPLGTAFTE
      181 AELRAIVDIA ARHGARVIAD EIWAPVVYGS RHVAAASVSE AAAEVVVTLV SASKGWNLPG
      241 LMCAQVILSN RRDAHDWDRI NMLHRMGAST VGIRANIAAY HHGESWLDEL LPYLRANRDH
      301 LARALPELAP GVEVNAPDGT YLSWVDFRAL ALPSEPAEYL LSKAKVALSP GIPFGAAVGS
      361 GFARLNFATT RAILDRAIEA IAAALRDIID
//