LOCUS CAB5247779.1 390 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE AMINOTRANSFERASE protein. ACCESSION LT708304-78 PROTEIN_ID CAB5247779.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0077" /note="Mb0077, -, len: 390 aa. Equivalent to Rv0075, len: 390 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 390 aa overlap). Probable aminotransferase (EC 2.6.1.-), similar to many CLASS-II PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASES (MALY/PATB SUBFAMILY) e.g. NP_302217.1|NC_002677 aminotransferase from Mycobacterium leprae (402 aa); PATB_BACSU|Q08432 putative aminotransferase b from Bacillus subtilis (387 aa), FASTA scores: opt: 684, E(): 5.4e-33, (31.3% identity in 384 aa overlap); etc. Also similar to several cystathionine beta-lyase (beta C-S lyase) e.g. AAK69425.1|AF276227_1|AF276227 from Corynebacterium glutamicum (368 aa); etc. Also similar to other proteins from Mycobacterium tuberculosis e.g. Rv2294, Rv0858c, etc. Protein product from Mb0077 detected using SWATH mass spectrometry. Mb0077 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MQDSIFNLLT EEQLRGRNTL KWNYFGPDVV PLWLAEMDFP TAPAVLDGVR ACVDNEEFGY 61 PPLGEDSLPR ATADWCRQRY GWCPRPDWVR VVPDVLKGME VVVEFLTRPE SPVALPVPAY 121 MPFFDVLHVT GRQRVEVPMV QQDSGRYLLD LDALQAAFVR GAGSVIICNP NNPLGTAFTE 181 AELRAIVDIA ARHGARVIAD EIWAPVVYGS RHVAAASVSE AAAEVVVTLV SASKGWNLPG 241 LMCAQVILSN RRDAHDWDRI NMLHRMGAST VGIRANIAAY HHGESWLDEL LPYLRANRDH 301 LARALPELAP GVEVNAPDGT YLSWVDFRAL ALPSEPAEYL LSKAKVALSP GIPFGAAVGS 361 GFARLNFATT RAILDRAIEA IAAALRDIID //