LOCUS CAB5247778.1 411 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Xaa- Pro dipeptidase (EC protein. ACCESSION LT708304-77 PROTEIN_ID CAB5247778.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0076" /EC_number="3.4.13.9" /note="Mb0076, -, len: 411 aa. Equivalent to Rv0074, len: 411 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 411 aa overlap). Conserved hypothetical protein, similar to Rv2915c|MTCY338.03c CONSERVED HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis, and showing some simlarity to various enzymes or hypothetical proteins from other organisms, eg NP_243801.1|NC_002570 aryldialkylphosphatase from Bacillus halodurans (394 aa); NP_421471.1|NC_002696 putativ Xaa-Pro dipeptidase from Caulobacter crescentus (429 aa); NP_343436.1|NC_002754 Prolidase (Xaa-Pro dipeptidase) (pepQ-like2) from Sulfolobus solfataricus (408 aa); Q50432|M91040 ORGANO PHOSPHATE ACID ANHYDRASE OPAB from MYCOBACTERIUM SP. (409 aa), FASTA scores: opt: 166, E(): 3.9e-11, (31.2% identity in 430 aa overlap); etc. Protein product from Mb0076 detected using SWATH mass spectrometry. Mb0076 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MGDLSISQVS ARPGRIGIRA RQMFDGYRFQ RGPVLVVVED GRISAVDFAG SACPDMNLVD 61 LGESTLLPGL VDAHAHLCWD PDGRPEDLAG DPHAVLVGRA RRHAAAALRS GITTIRDLGD 121 RDYAALALRE EYRQKTTVGP ELVVSGPPLT RSGGHCWFLG GVADSVEELV DAVQERAARG 181 ADWIKVMATG GFVTTASDPW QPQYGSGQLA AVVAAAEQVG LPVTAHAHAT AGIAAAVAAG 241 VDGIEHCTFL SEGSAAASPD VVEAIVAQGV WCGMTIPRVY PEMPENLVAV VQDGWRNIRR 301 LIDAGARVAL STDAGVAPGR RHDVLPDDLV YLSRHGFTST EVLTGATAAA AASCGLGHRK 361 GRIAPGYDAD LLAVAAGVDH DPAGLCDVKA VWRSGTQVPL QASAVGYNTP S //