LOCUS       CAB5247778.1             411 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Xaa-
            Pro dipeptidase (EC protein.
ACCESSION   LT708304-77
PROTEIN_ID  CAB5247778.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0076"
                     /EC_number="3.4.13.9"
                     /note="Mb0076, -, len: 411 aa. Equivalent to Rv0074, len:
                     411 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 411 aa overlap). Conserved
                     hypothetical protein, similar to Rv2915c|MTCY338.03c
                     CONSERVED HYPOTHETICAL PROTEIN from Mycobacterium
                     tuberculosis, and showing some simlarity to various
                     enzymes or hypothetical proteins from other organisms, eg
                     NP_243801.1|NC_002570 aryldialkylphosphatase from Bacillus
                     halodurans (394 aa); NP_421471.1|NC_002696 putativ Xaa-Pro
                     dipeptidase from Caulobacter crescentus (429 aa);
                     NP_343436.1|NC_002754 Prolidase (Xaa-Pro dipeptidase)
                     (pepQ-like2) from Sulfolobus solfataricus (408 aa);
                     Q50432|M91040 ORGANO PHOSPHATE ACID ANHYDRASE OPAB from
                     MYCOBACTERIUM SP. (409 aa), FASTA scores: opt: 166, E():
                     3.9e-11, (31.2% identity in 430 aa overlap); etc. Protein
                     product from Mb0076 detected using SWATH mass
                     spectrometry. Mb0076 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MGDLSISQVS ARPGRIGIRA RQMFDGYRFQ RGPVLVVVED GRISAVDFAG SACPDMNLVD
       61 LGESTLLPGL VDAHAHLCWD PDGRPEDLAG DPHAVLVGRA RRHAAAALRS GITTIRDLGD
      121 RDYAALALRE EYRQKTTVGP ELVVSGPPLT RSGGHCWFLG GVADSVEELV DAVQERAARG
      181 ADWIKVMATG GFVTTASDPW QPQYGSGQLA AVVAAAEQVG LPVTAHAHAT AGIAAAVAAG
      241 VDGIEHCTFL SEGSAAASPD VVEAIVAQGV WCGMTIPRVY PEMPENLVAV VQDGWRNIRR
      301 LIDAGARVAL STDAGVAPGR RHDVLPDDLV YLSRHGFTST EVLTGATAAA AASCGLGHRK
      361 GRIAPGYDAD LLAVAAGVDH DPAGLCDVKA VWRSGTQVPL QASAVGYNTP S
//