LOCUS       CAB5247777.1              48 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            GLUTAMINE-TRANSPORT PROTEIN ABC TRANSPORTER GLNQ protein.
ACCESSION   LT708304-76
PROTEIN_ID  CAB5247777.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0075"
                     /note="Mb0075 found to be expressed during exponential
                     growth in Sauton's minimal media by
                     RNA-sequencing.,Mb0075, -, len: 48 aa. Equivalent to 3'
                     end of Rv0073, len: 330 aa, from Mycobacterium
                     tuberculosis strain H37Rv, (100.0% identity in 70 aa
                     overlap). Probable glutamine-transport ATP-binding protein
                     ABC-transporter (see citation below), similar to many
                     ATP-binding proteins e.g. NP_070646.1|NC_000917 ABC
                     transporter ATP-binding protein from Archaeoglobus
                     fulgidus (231 aa); T34822 ABC-transporter ATP binding
                     protein from Streptomyces coelicolor (230 aa);
                     YBJZ_ECOLI|P75831 hypothetical ABC transporter ATP-binding
                     protein from Escherichia coli (648 aa), FASTA scores: opt:
                     531, E(): 6.8e-30, (38.6% identity in 233 aa overlap);
                     etc. Also highly similar to Y0A4_MYCT|Q50734|MTCY9C4.04c
                     hypothetical ABC transporter ATP-binding protein from
                     Mycobacterium tuberculosis (330 aa), FASTA scores: E(): 0,
                     (83.3% identity in 330 aa overlap). Contains PS00017
                     ATP/GTP-binding site motif A (P-loop), PS00211 ABC
                     transporters family signature, and PS00889 Cyclic
                     nucleotide-binding domain signature 2. BELONGS TO THE
                     ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).
                     Note that supposed act with near ORF Rv0072|MTV030.16
                     transmembrane ABC-transporter.
                     REMARK-M.bovis-M.tuberculosis: In Mycobacterium
                     tuberculosis strain H37Rv, Rv0073 exists as a single gene.
                     In Mycobacterium bovis, a frameshift due to a single base
                     deletion (a-*) splits Rv0073 into 2 parts, Mb0074 and
                     Mb0075. Protein product from Mb0075 detected using SWATH
                     mass spectrometry."
BEGIN
        1 MLFHLPRSAT VRARSDATAV GYTVQAFRER LGVGGLRDLI EHRALAND
//