LOCUS CAB03943.1 435 aa PRT CON 06-FEB-2024
DEFINITION Caenorhabditis elegans Isocitrate dehydrogenase [NADP] protein.
ACCESSION BX284606-2670
PROTEIN_ID CAB03943.1
SOURCE Caenorhabditis elegans
ORGANISM Caenorhabditis elegans
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
Caenorhabditis.
REFERENCE 1 (bases 1 to 17718942)
AUTHORS WormBase.
CONSRTM WormBase Consortium
JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European
Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email:
help@wormbase.org
REFERENCE 2 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project:
Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome
Institute at Washington University, St. Louis, MO 63110, USA.
REFERENCE 3 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
CONSRTM Caenorhabditis elegans Sequencing Consortium
TITLE Genome sequence of the nematode C. elegans: a platform for
investigating biology
JOURNAL Science 282(5396), 2012-2018(1998).
COMMENT Annotated features correspond to WormBase release WS292.
Protein-coding gene structures below are the result of integration
and manual review of the following types of data: ab initio
predictions by Genefinder (P. Green and L. Hillier, pers. comm.);
alignments to published proteins and cDNAs; genome sequence
conservation with other nematodes (e.g. to C. briggsae using WABA:
Genome Res. 2000. 10:1115-1125); sequence features (such as
trans-splice and polyA sites).
Sources of data: large-scale EST projects of Yuji Kohara
(http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome
cloning project (http://worfdb.dfci.harvard.edu); RST large-scale
sequencing project (Genome Res. 2009. 19:2334-2342); IST library
(Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010
Unpublished); UTRome EST data submission (UTRome v1 Mangone M.
Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep
sequencing data (454 read clusters - Makedonka Mitreva,
unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66);
Numerous data sets from the modENCODE project (Science. 2010.
330:1775-87); Individual C. elegans Nucleotide Database
submissions; Personal communications with C. elegans researchers;
Non-Coding gene structures below are derived using the following
methods and data: ab initio prediction of tRNAs by tRNAscan-SE
(Nucl. Acids. Res., 25, 955-964); integration and appraisal of
miRNAs from miRBase (http://www.mirbase.org); integration and
appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell.
2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87);
manual curation of novel published ncRNAs from the literature.
FEATURES Qualifiers
source /organism="Caenorhabditis elegans"
/chromosome="X"
/strain="Bristol N2"
/mol_type="genomic DNA"
/db_xref="taxon:6239"
protein /transl_table=1
/gene="idh-2"
/locus_tag="CELE_C34F6.8"
/standard_name="C34F6.8"
/note="Confirmed by transcript evidence"
/db_xref="EnsemblGenomes-Gn:WBGene00007942"
/db_xref="EnsemblGenomes-Tr:C34F6.8.1"
/db_xref="EnsemblGenomes-Tr:C34F6.8.2"
/db_xref="EnsemblGenomes-Tr:C34F6.8.3"
/db_xref="GOA:O17643"
/db_xref="InterPro:IPR004790"
/db_xref="InterPro:IPR019818"
/db_xref="InterPro:IPR024084"
/db_xref="UniProtKB/TrEMBL:O17643"
/db_xref="WormBase:WBGene00007942"
intron_pos 53:0 (1/5)
intron_pos 79:0 (2/5)
intron_pos 255:2 (3/5)
intron_pos 306:1 (4/5)
intron_pos 376:2 (5/5)
BEGIN
1 MLSRLTSRNV LLARNVATAA TQERQKIKVD NPVVDLDGDE MTRIIWKEIK NKLILPYLDL
61 DIKYYDLGLE YRDETNDQVT IDAAHAILEH SVGIKCATIT PDEARIKEFN LKKMWLSPNG
121 TIRNILGGTV FREPILCKNI PRLVPGWTQP ITIGRHAFGD QYKCTDLVIP SGSTLQLLVN
181 KPDGSKDVHN VYDFKKSGGV GLAMYNTDES IKGFAHSCFQ YALMKQWPLY LSTKNTILKK
241 YDGRFKDIFQ DIYEKKYEAD FKNNKIWYEH RLIDDQVAQA LKSSGGFVWA CKNYDGDVQS
301 DIVAQGYGSL GLMSSVLMCP DGKTIEAEAA HGTVTRHYRE HQKGNSTSTN PIASIFAWTR
361 GLHHRGVLDN NEALKTFSLT LEKACIDTVE EGKMTKDLSI CIHGTKKGTE KGAYLITEDF
421 LSAIDTKMAE LMRQD
//