LOCUS CAA93756.2 882 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Dual specificity tyrosine-phosphorylation- regulated kinase mbk-1 protein. ACCESSION BX284606-3557 PROTEIN_ID CAA93756.2 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="mbk-1" /locus_tag="CELE_T04C10.1" /standard_name="T04C10.1" /note="Confirmed by transcript evidence" /db_xref="EnsemblGenomes-Gn:WBGene00003149" /db_xref="EnsemblGenomes-Tr:T04C10.1" /db_xref="WormBase:WBGene00003149" intron_pos 116:0 (1/10) intron_pos 149:0 (2/10) intron_pos 172:1 (3/10) intron_pos 207:0 (4/10) intron_pos 265:2 (5/10) intron_pos 325:2 (6/10) intron_pos 391:1 (7/10) intron_pos 661:0 (8/10) intron_pos 764:2 (9/10) intron_pos 858:0 (10/10) BEGIN 1 MNTADVPDNL QSWGQQPSSS YSNTQQHSQM TNLPPINHNN LCDTEPMNED FQLQDVQADE 61 LQKQQKQQEQ QHIQQQNAQR FIAQSRQPHS NILRFPQPPI TSIKTNSHAF YPQQEVTQVR 121 PKKHRVSMTN AEAALTPGMP PEKQAAKKRN IGQFSTDTVP AGIGMIGIPF ESTSKPLQIQ 181 QFRNPQDAPV RKLTSDLIKT YKAINESFYL RKQVRRDRHK SQDAGKPKGS KDGSGASLTD 241 TFSIHNAIPI TSSDNHYQQD AHQNAPPLLD TNAPPTSTMV VPMRTETDLQ QQQRQKSSRG 301 GPYNNGYDDQ NYDYILKNGE IFDKRYVILS DTPVGKGSFG QVTKAYDTLN KEEVAIKIIK 361 NKKTFFDQAQ IEIHLLELTN AHDKDNKYNI VTLKGHFVHR AHLCLVFELL SYNLYDLLKN 421 TSFRGVSLNL ARKFAQQLGK TLLFLSSPEL SIIHCDLKPE NVLLVNAKRS QIRVIDFGSS 481 CQTGHRIYQY IQSRFYRSPE VLLGIAYDTK IDMWSLGCIL VEMHTGEPLF AGSSEVDQMM 541 KIVEVLGMPP KEMLDIGPKT HKYFDKTEDG IYYCKKTRDG YRHTYKAPGA RKLHEILGVT 601 SGGPGGRRLG EPGHSVEDYS KFKDLIKRML QFDPKQRISP YYVVRHPFLK QKEERVPSQP 661 PVSHSNLQQQ QQLYIQQPSS QMSQVMESPS VGSVYVEDNG MYRQAPGSSA NPISVTSSFD 721 EGDAMEVDAG RRRFSAHQQN YHNPNYQYSQ PQQQQQQQYQ QTQRTQLEQQ QKQAQLQQQL 781 QQQQMQQQQQ QQQQRQHMPQ AQSSSQQHLQ SRARPRQQDQ NEWRNQFELD DTFQQKQRKV 841 DDSVSNQISR NQFNPQQVSM THGNVNANNR EMEKLDYPNN KL //