LOCUS CAA91495.1 1268 aa PRT CON 06-FEB-2024
DEFINITION Caenorhabditis elegans Multidrug resistance protein pgp-3 protein.
ACCESSION BX284606-2708
PROTEIN_ID CAA91495.1
SOURCE Caenorhabditis elegans
ORGANISM Caenorhabditis elegans
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
Caenorhabditis.
REFERENCE 1 (bases 1 to 17718942)
AUTHORS WormBase.
CONSRTM WormBase Consortium
JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European
Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email:
help@wormbase.org
REFERENCE 2 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project:
Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome
Institute at Washington University, St. Louis, MO 63110, USA.
REFERENCE 3 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
CONSRTM Caenorhabditis elegans Sequencing Consortium
TITLE Genome sequence of the nematode C. elegans: a platform for
investigating biology
JOURNAL Science 282(5396), 2012-2018(1998).
COMMENT Annotated features correspond to WormBase release WS292.
Protein-coding gene structures below are the result of integration
and manual review of the following types of data: ab initio
predictions by Genefinder (P. Green and L. Hillier, pers. comm.);
alignments to published proteins and cDNAs; genome sequence
conservation with other nematodes (e.g. to C. briggsae using WABA:
Genome Res. 2000. 10:1115-1125); sequence features (such as
trans-splice and polyA sites).
Sources of data: large-scale EST projects of Yuji Kohara
(http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome
cloning project (http://worfdb.dfci.harvard.edu); RST large-scale
sequencing project (Genome Res. 2009. 19:2334-2342); IST library
(Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010
Unpublished); UTRome EST data submission (UTRome v1 Mangone M.
Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep
sequencing data (454 read clusters - Makedonka Mitreva,
unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66);
Numerous data sets from the modENCODE project (Science. 2010.
330:1775-87); Individual C. elegans Nucleotide Database
submissions; Personal communications with C. elegans researchers;
Non-Coding gene structures below are derived using the following
methods and data: ab initio prediction of tRNAs by tRNAscan-SE
(Nucl. Acids. Res., 25, 955-964); integration and appraisal of
miRNAs from miRBase (http://www.mirbase.org); integration and
appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell.
2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87);
manual curation of novel published ncRNAs from the literature.
FEATURES Qualifiers
source /organism="Caenorhabditis elegans"
/chromosome="X"
/strain="Bristol N2"
/mol_type="genomic DNA"
/db_xref="taxon:6239"
protein /transl_table=1
/gene="pgp-3"
/locus_tag="CELE_ZK455.7"
/standard_name="ZK455.7"
/note="Confirmed by transcript evidence"
/db_xref="EnsemblGenomes-Gn:WBGene00003997"
/db_xref="EnsemblGenomes-Tr:ZK455.7.1"
/db_xref="EnsemblGenomes-Tr:ZK455.7.2"
/db_xref="WormBase:WBGene00003997"
intron_pos 35:0 (1/12)
intron_pos 69:1 (2/12)
intron_pos 117:0 (3/12)
intron_pos 260:2 (4/12)
intron_pos 435:0 (5/12)
intron_pos 503:0 (6/12)
intron_pos 594:1 (7/12)
intron_pos 627:1 (8/12)
intron_pos 704:0 (9/12)
intron_pos 790:0 (10/12)
intron_pos 971:2 (11/12)
intron_pos 1184:2 (12/12)
BEGIN
1 MKKTKVNPED DITLGKFTPK PSPQDSYQGN FFDVFRDADY KDYILFSGGL ILSAVNGALV
61 PFNSLIFEGI ANALMEGESQ YQNGTINMPW FSSEIKMFCL RYFYLGVALF LCSYFANSCL
121 YTLCERRLHC IRKKYLKSVL RQDAKWFDET TIGGLTQKMS SGIEKIKDGI GDKVGVLVGG
181 VATFISGVSI GFYMCWQLTL VMMITVPLQL GSMYLSAKHL NRATKNEMSA YSNAGGMANE
241 VIAGIRTVMA FNAQPFEINR YAHQLNEARR MGIRKAIILA ICTAFPLMLM FTCMAVAFWY
301 GATLAAAGAV SSGAVFAVFW AVLIGTRRLG EAAPHLGAIT GARLAIHDIF KVIDHEPEIK
361 CTSSEGKIPE KIQGKLTFDG IEFTYPTRPE LKILKGVSFE VNPGETVALV GHSGCGKSTS
421 IGLLMRFYNQ CAGMIKLDGI PIQEYNIRWL RSTIGIVQQE PIIFVATVAE NIRMGDVLIT
481 DQDIEEACKM ANAHEFICKL SDRYDTVIGA GAVQLSGGQK QRVAIARAIV RKPQILLLDE
541 ATSALDTESE RMVQTALDKA SEGRTTLCIA HRLSTIRNAS KILVFDQGLI AERGTHDELI
601 SKDDGIYASM VKAQEIERAK EDTTLDDEED EKTHRSFHRD SVTSDEEREL QQSLARDSTR
661 LRQSMISTTT QVPEWEIENA REEMIEEGAM EASLFDIFKY ASPEMRNIII SLVFTLIRGF
721 TWPAFSIVYG QLFKILSAGG DDVSIKALLN SLWFILLAFT GGISTLISGS LLGKAGETMS
781 GRLRMDVFRN IMQQDASYFD DSRHNVGSLT SRLATDAPNV QAAIDQRLAE VLTGIVSLFC
841 GVGVAFYYGW NMAPIGLATA LLLVVVQSSV AQYLKFRGQR DMDSAIEASR LVTESISNWK
901 TVQALTKQEY MYDAFTAASK SPHRRAIVRG LWQSLSFALA GSFVMWNFAI AYMFGLWLIS
961 NNWSTPYTVF QVIEALNMAS MSVMLAASYF PEYVRARISA GIMFTMIRQK SVIDNRGLTG
1021 DTPTIKGNIN MRGVYFAYPN RRRQLVLDGF NMSANFGQTV ALVGPSGCGK STTIQLIERY
1081 YDALCGSVKI DDSDIRDLSV KHLRDNIALV GQEPTLFNLT IRENITYGLE NITQDQVEKA
1141 ATLANIHTFV MGLPDGYDTS VGASGGRLSG GQKQRVAIAR AIVRDPKILL LDEATSALDT
1201 ESEKIVQEAL DKARLGRTCV VIAHRLSTIQ NADKIIVCRN GKAIEEGTHQ TLLARRGLYY
1261 RLVEKQSS
//