LOCUS CAA91472.2 650 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans FYVE, RhoGEF and PH domain-containing protein 6 protein. ACCESSION BX284606-2780 PROTEIN_ID CAA91472.2 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="frm-3" /locus_tag="CELE_H05G16.1" /standard_name="H05G16.1c" /note="Confirmed by transcript evidence" /db_xref="EnsemblGenomes-Gn:WBGene00009932" /db_xref="EnsemblGenomes-Tr:F52D10.6" /db_xref="GOA:G5EDC0" /db_xref="InterPro:IPR000219" /db_xref="InterPro:IPR001849" /db_xref="InterPro:IPR011993" /db_xref="InterPro:IPR035899" /db_xref="UniProtKB/TrEMBL:G5EDC0" /db_xref="WormBase:WBGene00001490" intron_pos 54:2 (1/9) intron_pos 155:0 (2/9) intron_pos 187:0 (3/9) intron_pos 229:2 (4/9) intron_pos 282:2 (5/9) intron_pos 432:0 (6/9) intron_pos 500:1 (7/9) intron_pos 574:0 (8/9) intron_pos 625:2 (9/9) BEGIN 1 MFFSDSVSEF GNISDIQEPL YQSVNKKKDV IVGINSTFSS ETICTSEPIL KVNKKPRKRM 61 SRSANDTSEL NKYNSSDSGG LSIGDPTAGS NDSLRLMKRD HSSDYQLRHD YAVMRTSQST 121 ASVGTPSKEI EMSLENDVDN YPPSCSSEYY ITRKDFGKPE PQLANVLKEF YWKELVYSKD 181 MRLINESFFN KIKDDVVDCR FLKELFGSLK ELPPIHQPLI DALRESSNEP EDSKAAMVAP 241 VLLATVHNLT PLYQSLVQNF PIYVSALDQL YRSKIPFRTI MSKFESSKEC YTQVNWILLK 301 ILNRLINWQP VLARVIEIQL SECGNDTETT AFGVAMDKII EFAKKTKATR QSLEEYIHVL 361 QVERDTGLVG ILTHPNRKIL RVGFVLRSAR RAPCCRIMVL CSDRILFGHR GVNLDGNFFT 421 VHAEFKLKGM MIDEGDTYKV MDGENNVITL HNADISIVFA APDRASWIED ITEAIKNAAR 481 AKIDLPSLVM EKKEENDIDM TKVLLPEESP VSKMSPLQIC WYRKCSFGRK DVNKMITNTM 541 CGYLKRKLRN SSGWQDLWVV MCCHTLYFYR NHNEREPLAH LSLMDYGVGL PTVADKIDNH 601 ENCFKLFYGS HTYFFRTDSY YFFERWVDSI FQAAISRDSL DVVTALALRI //