LOCUS CAA58284.1 1101 aa PRT HUM 07-OCT-1996
DEFINITION Homo sapiens idem protein.
ACCESSION X83368-1
PROTEIN_ID CAA58284.1
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Stoyanov B., Volinia S., Hanck T., Rubio I., Loubtchenkov M.,
Malek D., Stoyanova S., Vanhaesebroeck B., Dhand R., Nuernberg B.,
Gierschik P., Seedorf K., Hsuan J.J., Waterfield M.D., Wetzker R.
TITLE Cloning and characterization of a G protein-activated human
phosphoinositide-3 kinase
JOURNAL Science, e1252229 269(5224), 690-693(1995).
PUBMED 7624799
REFERENCE 2
AUTHORS Waterfield M.D.
JOURNAL Submitted (08-DEC-1994) to the INSDC. M.D. Waterfield, Ludwig-Inst.
for Cancer Research, Courtauld Building, 91 Riding House Street,
London, W1P 8BT, UK
REMARK Revised by [3]
REFERENCE 3 (bases 1 to 5397)
AUTHORS Waterfield M.D.
JOURNAL Submitted (23-AUG-1996) to the INSDC. M.D. Waterfield, Ludwig-Inst.
for Cancer Research, Courtauld Building, 91 Riding House Street,
London, W1P 8BT, UK
COMMENT X83368 is homologous to M93252.
FEATURES Qualifiers
source /db_xref="H-InvDB:HIT000323949"
/organism="Homo sapiens"
/mol_type="mRNA"
/cell_line="U937"
/db_xref="taxon:9606"
protein /note="phosphatidylinositol 3 kinase gamma, p110 gamma"
/note="activated by G protein alpha and betagammma
subunits"
/db_xref="GOA:P48736"
/db_xref="H-InvDB:HIT000323949.13"
/db_xref="HGNC:HGNC:8978"
/db_xref="InterPro:IPR000341"
/db_xref="InterPro:IPR000403"
/db_xref="InterPro:IPR001263"
/db_xref="InterPro:IPR002420"
/db_xref="InterPro:IPR003113"
/db_xref="InterPro:IPR008290"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR015433"
/db_xref="InterPro:IPR016024"
/db_xref="InterPro:IPR018936"
/db_xref="InterPro:IPR029071"
/db_xref="InterPro:IPR035892"
/db_xref="InterPro:IPR036940"
/db_xref="InterPro:IPR042236"
/db_xref="PDB:1E8Y"
/db_xref="PDB:1E8Z"
/db_xref="PDB:1HE8"
/db_xref="PDB:2A4Z"
/db_xref="PDB:2A5U"
/db_xref="PDB:2CHW"
/db_xref="PDB:2CHX"
/db_xref="PDB:2CHZ"
/db_xref="PDB:2V4L"
/db_xref="PDB:3APC"
/db_xref="PDB:3APD"
/db_xref="PDB:3APF"
/db_xref="PDB:3CSF"
/db_xref="PDB:3CST"
/db_xref="PDB:3DBS"
/db_xref="PDB:3DPD"
/db_xref="PDB:3ENE"
/db_xref="PDB:3IBE"
/db_xref="PDB:3L08"
/db_xref="PDB:3L13"
/db_xref="PDB:3L16"
/db_xref="PDB:3L17"
/db_xref="PDB:3L54"
/db_xref="PDB:3LJ3"
/db_xref="PDB:3MJW"
/db_xref="PDB:3ML8"
/db_xref="PDB:3ML9"
/db_xref="PDB:3NZS"
/db_xref="PDB:3NZU"
/db_xref="PDB:3OAW"
/db_xref="PDB:3P2B"
/db_xref="PDB:3PRE"
/db_xref="PDB:3PRZ"
/db_xref="PDB:3PS6"
/db_xref="PDB:3QAQ"
/db_xref="PDB:3QAR"
/db_xref="PDB:3QJZ"
/db_xref="PDB:3QK0"
/db_xref="PDB:3R7Q"
/db_xref="PDB:3R7R"
/db_xref="PDB:3S2A"
/db_xref="PDB:3SD5"
/db_xref="PDB:3T8M"
/db_xref="PDB:3TJP"
/db_xref="PDB:3TL5"
/db_xref="PDB:3ZVV"
/db_xref="PDB:3ZW3"
/db_xref="PDB:4ANU"
/db_xref="PDB:4ANV"
/db_xref="PDB:4ANW"
/db_xref="PDB:4ANX"
/db_xref="PDB:4AOF"
/db_xref="PDB:4DK5"
/db_xref="PDB:4EZJ"
/db_xref="PDB:4EZK"
/db_xref="PDB:4EZL"
/db_xref="PDB:4F1S"
/db_xref="PDB:4FA6"
/db_xref="PDB:4FAD"
/db_xref="PDB:4FHJ"
/db_xref="PDB:4FHK"
/db_xref="PDB:4FJY"
/db_xref="PDB:4FJZ"
/db_xref="PDB:4FLH"
/db_xref="PDB:4FUL"
/db_xref="PDB:4G11"
/db_xref="PDB:4GB9"
/db_xref="PDB:4HLE"
/db_xref="PDB:4HVB"
/db_xref="PDB:4J6I"
/db_xref="PDB:4KZ0"
/db_xref="PDB:4KZC"
/db_xref="PDB:4PS3"
/db_xref="PDB:4PS7"
/db_xref="PDB:4PS8"
/db_xref="PDB:4URK"
/db_xref="PDB:4WWN"
/db_xref="PDB:4WWO"
/db_xref="PDB:4WWP"
/db_xref="PDB:4XX5"
/db_xref="PDB:4XZ4"
/db_xref="PDB:5EDS"
/db_xref="PDB:5G2N"
/db_xref="PDB:5G55"
/db_xref="PDB:5JHA"
/db_xref="PDB:5JHB"
/db_xref="PDB:5KAE"
/db_xref="PDB:5OQ4"
/db_xref="PDB:5T23"
/db_xref="PDB:6AUD"
/db_xref="PDB:6C1S"
/db_xref="PDB:6FH5"
/db_xref="PDB:6GQ7"
/db_xref="UniProtKB/Swiss-Prot:P48736"
BEGIN
1 MELENYKQPV VLREDNCRRR RRMKPRSAAS LSSMELIPIE FVLPTSQRKC KSPETALLHV
61 AGHGNVEQMK AQVWLRALET SVAADFYHRL GPHHFLLLYQ KKGQWYEIYD KYQVVQTLDC
121 LRYWKATHRS PGQIHLVQRH PPSEESQAFQ RQLTALIGYD VTDVSNVHDD ELEFTRRGLV
181 TPRMAEVASR DPKLYAMHPW VTSKPLPEYL WKKIANNCIF IVIHRSTTSQ TIKVSPDDTP
241 GAILQSFFTK MAKKKSLMDI PESQSEQDFV LRVCGRDEYL VGETPIKNFQ WVRHCLKNGE
301 EIHVVLDTPP DPALDEVRKE EWPLVDDCTG VTGYHEQLTI HGKDHESVFT VSLWDCDRKF
361 RVKIRGIDIP VLPRNTDLTV FVEANIQHGQ QVLCQRRTSP KPFTEEVLWN VWLEFSIKIK
421 DLPKGALLNL QIYCGKAPAL SSKASAESPS SESKGKVRLL YYVNLLLIDH RFLLRRGEYV
481 LHMWQISGKG EDQGSFNADK LTSATNPDKE NSMSISILLD NYCHPIALPK HQPTPDPEGD
541 RVRAEMPNQL RKQLEAIIAT DPLNPLTAED KELLWHFRYE SLKHPKAYPK LFSSVKWGQQ
601 EIVAKTYQLL ARREVWDQSA LDVGLTMQLL DCNFSDENVR AIAVQKLESL EDDDVLHYLL
661 QLVQAVKFEP YHDSALARFL LKRGLRNKRI GHFLFWFLRS EIAQSRHYQQ RFAVILEAYL
721 RGCGTAMLHD FTQQVQVIEM LQKVTLDIKS LSAEKYDVSS QVISQLKQKL ENLQNSQLPE
781 SFRVPYDPGL KAGALAIEKC KVMASKKKPL WLEFKCADPT ALSNETIGII FKHGDDLRQD
841 MLILQILRIM ESIWETESLD LCLLPYGCIS TGDKIGMIEI VKDATTIAKI QQSTVGNTGA
901 FKDEVLNHWL KEKSPTEEKF QAAVERFVYS CAGYCVATFV LGIGDRHNDN IMITETGNLF
961 HIDFGHILGN YKSFLGINKE RVPFVLTPDF LFVMGTSGKK TSPHFQKFQD ICVKAYLALR
1021 HHTNLLIILF SMMLMTGMPQ LTSKEDIEYI RDALTVGKNE EDAKKYFLDQ IEVCRDKGWT
1081 VQFNWFLHLV LGIKQGEKHS A
//