LOCUS CAA19143.1 336 aa PRT BCT 16-APR-2005
DEFINITION Mycobacterium leprae hypothetical protein MLCB2407.03c protein.
ACCESSION AL023596-3
PROTEIN_ID CAA19143.1
SOURCE Mycobacterium leprae
ORGANISM Mycobacterium leprae
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium.
REFERENCE 1 (bases 1 to 35615)
AUTHORS Seeger K., Harris D.
JOURNAL Unpublished.
REFERENCE 2 (bases 1 to 35615)
AUTHORS Parkhill J., Barrell B.G., Rajandream M.A.
JOURNAL Submitted (18-MAY-1998) to the INSDC. Mycobacterium leprae
sequencing project, Sanger Centre, Wellcome Trust Genome Campus,
Hinxton, Cambridge CB10 1SA E-mail: barrell@sanger.ac.uk Cosmids
supplied by Dr. Stewart T. Cole, [3] Unite de Genetique Moleculaire
Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris
Cedex 15, France Requests for cosmids should be sent to Karin
Eiglmeier (kei@pasteur.fr).
REFERENCE 3 (bases 1 to 35615)
AUTHORS Eiglmeier K., Honore N., Woods S.A., Caudron B., Cole S.T.
TITLE Use of an ordered cosmid library to deduce the genomic organization
of Mycobacterium leprae
JOURNAL Mol. Microbiol. 7(2), 197-206(1993).
PUBMED 8446027
COMMENT Notes:
The Sanger Centre is funded to complete the sequence of M. leprae
by the Heiser Program for Research in Leprosy and Tuberculosis of
The New York Community Trust.
Work in Paris is supported by the Heiser Trust, the Association
Francaise Raoul Follereau and the Groupement de Recherches et des
Etudes des Genomes (GIP-GREG).
Details of M. leprae sequencing at the Sanger Centre
are available on the World Wide Web.
(URL, http://www.sanger.ac.uk/Projects/)
CDS are numbered using the following system eg MLCB33.01c.
ML (M. leprae), cB33 (cosmid name), .01 (first CDS),
c (complementary strand).
The more significant matches with motifs in the PROSITE
database are also included but some of these may be fortuitous.
The length in codons is given for each CDS.
Usually the highest scoring match found by fasta -o is given for
CDS which show significant similarity to other CDS in the database.
The position of possible ribosome binding site sequences are
given where these have been used to deduce the initiation codon.
All CDS over 100 codons have been analysed. Gene prediction
is based on positional base preference in codons especially
where there is an increase in the observed/expected third
position G + C. CAUTION: We may not have predicted the
correct initiation codon. Where possible we choose an
initiation codon (atg, gtg, or ttg) which is preceded by an
upstream ribosome binding site sequence (optimally 5-13bp
before the initiation codon). If this cannot be identified
we choose the most upstream initiation codon.
IMPORTANT: This sequence MAY NOT be the entire insert of
the sequenced clone. It may be shorter because we only
sequence overlapping sections once, or longer, because we
arrange for a small overlap between neighbouring submissions.
Cosmid B2407 is overlapped by EMBL:ML023 L518 at the 5' end
and EMBL:MLB577COS B577 at the 3' end.
FEATURES Qualifiers
source /organism="Mycobacterium leprae"
/mol_type="genomic DNA"
/clone="cosmid B2407"
/db_xref="taxon:1769"
protein /transl_table=11
/gene="MLCB2407.03c"
/note="MLCB2407.03c, unknown, len: 336 aa; identical to
ORF's TR:Q49930 L518_C3_195 (213 aa) and TR:Q49928
L518_C1_89 (122 aa) (EMBL;U00023). This sequence has a
single ORF, due an additional base in EMBL:U00023"
/db_xref="InterPro:IPR029063"
/db_xref="UniProtKB/TrEMBL:O69510"
BEGIN
1 MYSIELRKMG TLGCVKIISK ENVIIVAAKI SWTLRCLVFL LRFGFAFLFY SGIVNPIIIW
61 HGFAALLRYF LVKQGIPSGT AKHLAQIRAE FEEQSVQGQF KELYFDMTDR NIVVWSDIFS
121 RVFDRKAPVR ILEIGSWEGR STLFLLTYFT QGHLTAVDTW AGSDEHQHNA PSDLRSLEAR
181 FDSNLTPCAA RLTKRKGSSL HVLPQLLGEE QKFDVIYVDG SHFGDDVLAD GITAWRLLEK
241 GGILIFDDFL WPGYLRARAN PAWAINLFLK YHAGEYKILN VSYQVILQKK LVFNDRVLTS
301 LATVQYDDRR RFTKEFIKNL SSASQVMSGN MRPLER
//