LOCUS CAA06955.1 233 aa PRT HUM 07-OCT-2008 DEFINITION Homo sapiens bcl-10 protein. ACCESSION AJ006288-1 PROTEIN_ID CAA06955.1 SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 1877) AUTHORS Willis A.G. JOURNAL Submitted (21-MAY-1998) to the INSDC. Willis A.G., Academic Haematology, Institute Of Cancer Research, Sutton, Surrey SM2 5NG, UK. REFERENCE 2 AUTHORS Willis T.G., Jadayel D.M., Du M.Q., Peng H., Perry A.R., Abdul-Rauf M., Price H., Karran L., Majekodunmi O., Wlodarska I., Pan L., Crook T., Hamoudi R., Isaacson P., Dyer M.J. TITLE Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types JOURNAL Cell 96(1), 35-45(1999). PUBMED 9989495 FEATURES Qualifiers source /db_xref="H-InvDB:HIT000244101" /organism="Homo sapiens" /mol_type="mRNA" /cell_type="germinal centre B-cell" /db_xref="taxon:9606" protein /gene="bcl-10" /function="CARD-containing protein. Promotes apoptosis, activates NF-kappaB and suppresses transformation of rat embryo fibroblasts (REFs). Bcl10 is mutated in multiple tumor types" /db_xref="GOA:O95999" /db_xref="H-InvDB:HIT000244101.13" /db_xref="HGNC:HGNC:989" /db_xref="InterPro:IPR001315" /db_xref="InterPro:IPR011029" /db_xref="InterPro:IPR033238" /db_xref="InterPro:IPR042143" /db_xref="PDB:2MB9" /db_xref="PDB:6BZE" /db_xref="PDB:6GK2" /db_xref="UniProtKB/Swiss-Prot:O95999" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MEPTAPSLTE EDLTEVKKDA LENLRVYLCE KIIAERHFDH LRAKKILSRE DTEEISCRTS 61 SRKRAGKLLD YLQENPKGLD TLVESIRREK TQNFLIQKIT DEVLKLRNIK LEHLKGLKCS 121 SCEPFPDGAT NNLSRSNSDE SNFSEKLRAS TVMYHPEGES STTPFFSTNS SLNLPVLEVG 181 RTENTIFSST TLPRPGDPGA PPLPPDLQLE EEGTCANSSE MFLPLRSRTV SRQ //