LOCUS       BAB96595.2               938 aa    PRT              BCT 29-SEP-2018
DEFINITION  Escherichia coli str. K-12 substr. W3110 isoleucyl-tRNA
            synthetase protein.
ACCESSION   AP009048-26
PROTEIN_ID  BAB96595.2
SOURCE      Escherichia coli str. K-12 substr. W3110
  ORGANISM  Escherichia coli str. K-12 substr. W3110
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4646332)
  AUTHORS   Mori,H., Hirai,A., Morooka,N. and Horiuchi,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-AUG-2005) to the DDBJ/EMBL/GenBank databases.
            Contact:Hirotada Mori
            Graduate School of Biological Sciences, Nara Institute of Science
            and Technology; 8916-5 Takayama, Ikoma, Nara 630-0101, Japan
REFERENCE   2
  AUTHORS   Hayashi,K., Morooka,N., Yamamoto,Y., Fujita,K., Isono,K., Choi,S.,
            Ohtsubo,E., Baba,T., Wanner,B.L., Mori,H. and Horiuchi,T.
  TITLE     Highly accurate genome sequences of Escherichia coli K-12 strains
            MG1655 and W3110
  JOURNAL   Mol. Syst. Biol. 2, 2006.0007 (2006)
  REMARK    Publication Status: Online-Only
REFERENCE   3
  AUTHORS   Riley,M., Abe,T., Arnaud,M.B., Berlyn,M.K., Blattner,F.R.,
            Chaudhuri,R.R., Glasner,J.D., Horiuchi,T., Keseler,I.M.,
            Kosuge,T., Mori,H., Perna,N.T., Plunkett,G.III., Rudd,K.E.,
            Serres,M.H., Thomas,G.H., Thomson,N.R., Wishart,D. and Wanner,B.L.
  TITLE     Escherichia coli K-12: a cooperatively developed annotation
            snapshot--2005
  JOURNAL   Nucleic Acids Res. 34, 1-9 (2006)
REFERENCE   4
  AUTHORS   Yamamoto,Y., Aiba,H., Baba,T., Hayashi,K., Inada,T., Isono,K.,
            Itoh,T., Kimura,S., Kitagawa,M., Makino,K., Miki,T.,
            Mitsuhashi,N., Mizobuchi,K., Mori,H., Nakade,S., Nakamura,Y.,
            Nashimoto,H., Oshima,T., Oyama,S., Saito,N., Sampei,G., Satoh,Y.,
            Sivasundaram,S., Tagami,H., Takahashi,H., Takeda,J., Takemoto,K.,
            Uehara,K., Wada,C., Yamagata,S. and Horiuchi,T.
  TITLE     Construction of a contiguous 874-kb sequence of the Escherichia
            coli -K12 genome corresponding to 50.0-68.8 min on the linkage map
            and analysis of its sequence features
  JOURNAL   DNA Res. 4, 91-113 (1997)
REFERENCE   5
  AUTHORS   Itoh,T., Aiba,H., Baba,T., Hayashi,K., Inada,T., Isono,K.,
            Kasai,H., Kimura,S., Kitakawa,M., Kitagawa,M., Makino,K., Miki,T.,
            Mizobuchi,K., Mori,H., Mori,T., Motomura,K., Nakade,S.,
            Nakamura,Y., Nashimoto,H., Nishio,Y., Oshima,T., Saito,N.,
            Sampei,G., Seki,Y., Sivasundaram,S., Tagami,H., Takeda,J.,
            Takemoto,K., Wada,C., Yamamoto,Y. and Horiuchi,T.
  TITLE     A 460-kb DNA sequence of the Escherichia coli K-12 genome
            corresponding to the 40.1-50.0 min region on the linkage map
  JOURNAL   DNA Res. 3, 379-392 (1996)
REFERENCE   6
  AUTHORS   Aiba,H., Baba,T., Hayashi,K., Inada,T., Isono,K., Itoh,T.,
            Kasai,H., Kashimoto,K., Kimura,S., Kitakawa,M., Kitagawa,M.,
            Makino,K., Miki,T., Mizobuchi,K., Mori,H., Mori,T., Motomura,K.,
            Nakade,S., Nakamura,Y., Nashimoto,H., Nishio,Y., Oshima,T.,
            Saito,N., Sampei,G., Seki,Y., Sivasundaram,S., Tagami,H.,
            Takeda,J., Takemoto,K., Takeuchi,Y., Wada,C., Yamamoto,Y. and
            Horiuchi,T.
  TITLE     A 570-kb DNA sequence of the Escherichia coli K-12 genome
            corresponding to the 28.0-40.1 min region on the linkage map
  JOURNAL   DNA Res. 3, 363-377 (1996)
REFERENCE   7
  AUTHORS   Arn,E.A. and Abelson,J.N.
  TITLE     The 2'-5' RNA ligase of Escherichia coli. Purification, cloning,
            and genomic disruption
  JOURNAL   J. Biol. Chem. 271, 31145-31153 (1996)
REFERENCE   8
  AUTHORS   Oshima,T., Aiba,H., Baba,T., Fujita,K., Hayashi,K., Honjo,A.,
            Ikemoto,K., Inada,T., Itoh,T., Kajihara,M., Kanai,K.,
            Kashimoto,K., Kimura,S., Kitagawa,M., Makino,K., Masuda,S.,
            Miki,T., Mizobuchi,K., Mori,H., Motomura,K., Nakamura,Y.,
            Nashimoto,H., Nishio,Y., Saito,N., Sampei,G., Seki,Y., Tagami,H.,
            Takemoto,K., Wada,C., Yamamoto,Y., Yano,M. and Horiuchi,T.
  TITLE     A 718-kb DNA sequence of the Escherichia coli K-12 genome
            corresponding to the 12.7-28.0 min region on the linkage map
  JOURNAL   DNA Res. 3, 137-155 (1996)
REFERENCE   9
  AUTHORS   Fujita,N., Mori,H., Yura,T. and Ishihama,A.
  TITLE     Systematic sequencing of the Escherichia coli genome: analysis of
            the 2.4-4.1 min (110,917-193,643 bp) region
  JOURNAL   Nucleic Acids Res. 22, 1637-1639 (1994)
REFERENCE   10
  AUTHORS   Janosi,L., Shimizu,I. and Kaji,A.
  TITLE     Ribosome recycling factor (ribosome releasing factor) is essential
            for bacterial growth
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 91, 4249-4253 (1994)
REFERENCE   11
  AUTHORS   Allikmets,R., Gerrard,B., Court,D. and Dean,M.
  TITLE     Cloning and organization of the abc and mdl genes of Escherichia
            coli: relationship to eukaryotic multidrug resistance
  JOURNAL   Gene 136, 231-236 (1993)
REFERENCE   12
  AUTHORS   van Heeswijk,W.C., Rabenberg,M., Westerhoff,H.V. and Kahn,D.
  TITLE     The genes of the glutamine synthetase adenylylation cascade are
            not regulated by nitrogen in Escherichia coli
  JOURNAL   Mol. Microbiol. 9, 443-457 (1993)
REFERENCE   13
  AUTHORS   Zhao,S., Sandt,C.H., Feulner,G., Vlazny,D.A., Gray,J.A. and
            Hill,C.W.
  TITLE     Rhs elements of Escherichia coli K-12: complex composites of
            shared and unique components that have different evolutionary
            histories
  JOURNAL   J. Bacteriol. 175, 2799-2808 (1993)
REFERENCE   14
  AUTHORS   Yamada,M., Asaoka,S., Saier,M.H. Jr and Yamada,Y.
  TITLE     Characterization of the gcd gene from Escherichia coli K-12 W3110
            and regulation of its expression
  JOURNAL   J. Bacteriol. 175, 568-571 (1993)
REFERENCE   15
  AUTHORS   Cormack,R.S. and Mackie,G.A.
  TITLE     Structural requirements for the processing of Escherichia coli 5 S
            ribosomal RNA by RNase E in vitro
  JOURNAL   J. Mol. Biol. 228, 1078-1090 (1992)
REFERENCE   16
  AUTHORS   Gervais,F.G. and Drapeau,G.R.
  TITLE     Identification, cloning, and characterization of rcsF, a new
            regulator gene for exopolysaccharide synthesis that suppresses the
            division mutation ftsZ84 in Escherichia coli K-12
  JOURNAL   J. Bacteriol. 174, 8016-8022 (1992)
REFERENCE   17
  AUTHORS   Yamanaka,K., Ogura,T., Niki,H. and Hiraga,S.
  TITLE     Identification and characterization of the smbA gene, a suppressor
            of the mukB null mutant of Escherichia coli
  JOURNAL   J. Bacteriol. 174, 7517-7526 (1992)
REFERENCE   18
  AUTHORS   Condon,C., Philips,J., Fu,Z.Y., Squires,C. and Squires,C.L.
  TITLE     Comparison of the expression of the seven ribosomal RNA operons in
            Escherichia coli
  JOURNAL   EMBO J. 11, 4175-4185 (1992)
REFERENCE   19
  AUTHORS   Talarico,T.L., Ray,P.H., Dev,I.K., Merrill,B.M. and Dallas,W.S.
  TITLE     Cloning, sequence analysis, and overexpression of Escherichia coli
            folK, the gene coding for 7,8-dihydro-6-hydroxymethylpterin-
            pyrophosphokinase
  JOURNAL   J. Bacteriol. 174, 5971-5977 (1992)
REFERENCE   20
  AUTHORS   Arnqvist,A., Olsen,A., Pfeifer,J., Russell,D.G. and Normark,S.
  TITLE     The Crl protein activates cryptic genes for curli formation and
            fibronectin binding in Escherichia coli HB101
  JOURNAL   Mol. Microbiol. 6, 2443-2452 (1992)
REFERENCE   21
  AUTHORS   Li,S.J. and Cronan,J.E. Jr
  TITLE     The genes encoding the two carboxyltransferase subunits of
            Escherichia coli acetyl-CoA carboxylase
  JOURNAL   J. Biol. Chem. 267, 16841-16847 (1992)
REFERENCE   22
  AUTHORS   Yura,T., Mori,H., Nagai,H., Nagata,T., Ishihama,A., Fujita,N.,
            Isono,K., Mizobuchi,K. and Nakata,A.
  TITLE     Systematic sequencing of the Escherichia coli genome: analysis of
            the 0-2.4 min region
  JOURNAL   Nucleic Acids Res. 20, 3305-3308 (1992)
REFERENCE   23
  AUTHORS   Ghosh,S.K., Biswas,S.K., Paul,K. and Das,J.
  TITLE     Nucleotide and deduced amino acid sequence of the recA gene of
            Vibrio cholerae
  JOURNAL   Nucleic Acids Res. 20, 372 (1992)
REFERENCE   24
  AUTHORS   Smallshaw,J.E. and Kelln,R.A.
  TITLE     Cloning, nucleotide sequence and expression of the Escherichia
            coli K-12 pyrH gene encoding UMP kinase
  JOURNAL   Genetics (Life Sci. Adv.) 11, 59-65 (1992)
REFERENCE   25
  AUTHORS   O'Neill,G.P., Grygorczyk,R., Adam,M. and Ford-Hutchinson,A.W.
  TITLE     The nucleotide sequence of a voltage-gated chloride channel from
            the electric organ of Torpedo californica
  JOURNAL   Biochim. Biophys. Acta 1129, 131-134 (1991)
REFERENCE   26
  AUTHORS   Kajie,S., Ideta,R., Yamato,I. and Anraku,Y.
  TITLE     Molecular cloning and DNA sequence of dniR, a gene affecting
            anaerobic expression of the Escherichia coli hexaheme nitrite
            reductase
  JOURNAL   FEMS Microbiol. Lett. 67, 205-211 (1991)
REFERENCE   27
  AUTHORS   Hershfield,M.S., Chaffee,S., Koro-Johnson,L., Mary,A., Smith,A.A.
            and Short,S.A.
  TITLE     Use of site-directed mutagenesis to enhance the epitope-shielding
            effect of covalent modification of proteins with polyethylene
            glycol
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 88, 7185-7189 (1991)
REFERENCE   28
  AUTHORS   Shimizu,I. and Kaji,A.
  TITLE     Identification of the promoter region of the ribosome-releasing
            factor cistron (frr)
  JOURNAL   J. Bacteriol. 173, 5181-5187 (1991)
REFERENCE   29
  AUTHORS   Poulsen,L.K., Refn,A., Molin,S. and Andersson,P.
  TITLE     The gef gene from Escherichia coli is regulated at the level of
            translation
  JOURNAL   Mol. Microbiol. 5, 1639-1648 (1991)
REFERENCE   30
  AUTHORS   Poulsen,L.K., Refn,A., Molin,S. and Andersson,P.
  TITLE     Topographic analysis of the toxic Gef protein from Escherichia coli
  JOURNAL   Mol. Microbiol. 5, 1627-1637 (1991)
REFERENCE   31
  AUTHORS   Kawamukai,M., Utsumi,R., Takeda,K., Higashi,A., Matsuda,H.,
            Choi,Y.L. and Komano,T.
  TITLE     Nucleotide sequence and characterization of the sfs1 gene: sfs1 is
            involved in CRP*-dependent mal gene expression in Escherichia coli
  JOURNAL   J. Bacteriol. 173, 2644-2648 (1991)
REFERENCE   32
  AUTHORS   Hulton,C.S., Higgins,C.F. and Sharp,P.M.
  TITLE     ERIC sequences: a novel family of repetitive elements in the
            genomes of Escherichia coli, Salmonella typhimurium and other
            enterobacteria
  JOURNAL   Mol. Microbiol. 5, 825-834 (1991)
REFERENCE   33
  AUTHORS   Arigoni,F., Kaminski,P.A., Hennecke,H. and Elmerich,C.
  TITLE     Nucleotide sequence of the fixABC region of Azorhizobium
            caulinodans ORS571: similarity of the fixB product with eukaryotic
            flavoproteins, characterization of fixX, and identification of nifW
  JOURNAL   Mol. Gen. Genet. 225, 514-520 (1991)
REFERENCE   34
  AUTHORS   Munro,A.W., Ritchie,G.Y., Lamb,A.J., Douglas,R.M. and Booth,I.R.
  TITLE     The cloning and DNA sequence of the gene for the
            glutathione-regulated potassium-efflux system KefC of Escherichia
            coli
  JOURNAL   Mol. Microbiol. 5, 607-616 (1991)
REFERENCE   35
  AUTHORS   Mattick,J.S., Anderson,B.J., Cox,P.T., Dalrymple,B.P., Bills,M.M.,
            Hobbs,M. and Egerton,J.R.
  TITLE     Gene sequences and comparison of the fimbrial subunits
            representative of Bacteroides nodosus serotypes A to I: class I
            and class II strains
  JOURNAL   Mol. Microbiol. 5, 561-573 (1991)
REFERENCE   36
  AUTHORS   Company,M., Arenas,J. and Abelson,J.
  TITLE     Requirement of the RNA helicase-like protein PRP22 for release of
            messenger RNA from spliceosomes
  JOURNAL   Nature 349, 487-493 (1991)
REFERENCE   37
  AUTHORS   Umeda,M. and Ohtsubo,E.
  TITLE     Four types of IS1 with differences in nucleotide sequence reside
            in the Escherichia coli K-12 chromosome
  JOURNAL   Gene 98, 1-5 (1991)
REFERENCE   38
  AUTHORS   Hirvas,L., Koski,P. and Vaara,M.
  TITLE     The ompH gene of Yersinia enterocolitica: cloning, sequencing,
            expression, and comparison with known enterobacterial ompH
            sequences
  JOURNAL   J. Bacteriol. 173, 1223-1229 (1991)
REFERENCE   39
  AUTHORS   Bouvier,J. and Stragier,P.
  TITLE     Nucleotide sequence of the lsp-dapB interval in Escherichia coli
  JOURNAL   Nucleic Acids Res. 19, 180 (1991)
REFERENCE   40
  AUTHORS   Dicker,I.B. and Seetharam,S.
  TITLE     Cloning and nucleotide sequence of the firA gene and the
            firA200(Ts) allele from Escherichia coli
  JOURNAL   J. Bacteriol. 173, 334-344 (1991)
REFERENCE   41
  AUTHORS   Allen,B.L., Gerlach,G.F. and Clegg,S.
  TITLE     Nucleotide sequence and functions of mrk determinants necessary
            for expression of type 3 fimbriae in Klebsiella pneumoniae
  JOURNAL   J. Bacteriol. 173, 916-920 (1991)
REFERENCE   42
  AUTHORS   Grimm,B., Bull,A. and Breu,V.
  TITLE     Structural genes of glutamate 1-semialdehyde aminotransferase for
            porphyrin synthesis in a cyanobacterium and Escherichia coli
  JOURNAL   Mol. Gen. Genet. 225, 1-10 (1991)
REFERENCE   43
  AUTHORS   Chen,H., Lawrence,C.B., Bryan,S.K. and Moses,R.E.
  TITLE     Aphidicolin inhibits DNA polymerase II of Escherichia coli, an
            alpha-like DNA polymerase
  JOURNAL   Nucleic Acids Res. 18, 7185-7186 (1990)
REFERENCE   44
  AUTHORS   Mallonee,D.H., White,W.B. and Hylemon,P.B.
  TITLE     Cloning and sequencing of a bile acid-inducible operon from
            Eubacterium sp. strain VPI 12708
  JOURNAL   J. Bacteriol. 172, 7011-7019 (1990)
REFERENCE   45
  AUTHORS   Young,C., Collins-Emerson,J.M., Terzaghi,E.A. and Scott,D.B.
  TITLE     Nucleotide sequence of Rhizobium loti nodI
  JOURNAL   Nucleic Acids Res. 18, 6691 (1990)
REFERENCE   46
  AUTHORS   Chen,H., Sun,Y., Stark,T., Beattie,W. and Moses,R.E.
  TITLE     Nucleotide sequence and deletion analysis of the polB gene of
            Escherichia coli
  JOURNAL   DNA Cell Biol. 9, 613-635 (1990)
REFERENCE   47
  AUTHORS   Eriani,G., Delarue,M., Poch,O., Gangloff,J. and Moras,D.
  TITLE     Partition of tRNA synthetases into two classes based on mutually
            exclusive sets of sequence motifs
  JOURNAL   Nature 347, 203-206 (1990)
REFERENCE   48
  AUTHORS   Showalter,R.E. and Silverman,M.R.
  TITLE     Nucleotide sequence of a gene, hpt, for hypoxanthine
            phosphoribosyltransferase from Vibrio harveyi
  JOURNAL   Nucleic Acids Res. 18, 4621 (1990)
REFERENCE   49
  AUTHORS   Martin-Verstraete,I., Debarbouille,M., Klier,A. and Rapoport,G.
  TITLE     Levanase operon of Bacillus subtilis includes a fructose-specific
            phosphotransferase system regulating the expression of the operon
  JOURNAL   J. Mol. Biol. 214, 657-671 (1990)
REFERENCE   50
  AUTHORS   Henrich,B., Monnerjahn,U. and Plapp,R.
  TITLE     Peptidase D gene (pepD) of Escherichia coli K-12: nucleotide
            sequence, transcript mapping, and comparison with other peptidase
            genes
  JOURNAL   J. Bacteriol. 172, 4641-4651 (1990)
REFERENCE   51
  AUTHORS   Nunn,D., Bergman,S. and Lory,S.
  TITLE     Products of three accessory genes, pilB, pilC, and pilD, are
            required for biogenesis of Pseudomonas aeruginosa pili
  JOURNAL   J. Bacteriol. 172, 2911-2919 (1990)
REFERENCE   52
  AUTHORS   Rosenthal,E.R. and Calvo,J.M.
  TITLE     The nucleotide sequence of leuC from Salmonella typhimurium
  JOURNAL   Nucleic Acids Res. 18, 3072 (1990)
REFERENCE   53
  AUTHORS   Kang,P.J. and Craig,E.A.
  TITLE     Identification and characterization of a new Escherichia coli gene
            that is a dosage-dependent suppressor of a dnaK deletion mutation
  JOURNAL   J. Bacteriol. 172, 2055-2064 (1990)
REFERENCE   54
  AUTHORS   Wurgler,S.M. and Richardson,C.C.
  TITLE     Structure and regulation of the gene for dGTP triphosphohydrolase
            from Escherichia coli
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 87, 2740-2744 (1990)
REFERENCE   55
  AUTHORS   Schaaff,I., Hohmann,S. and Zimmermann,F.K.
  TITLE     Molecular analysis of the structural gene for yeast transaldolase
  JOURNAL   Eur. J. Biochem. 188, 597-603 (1990)
REFERENCE   56
  AUTHORS   Ricca,E. and Calvo,J.M.
  TITLE     The nucleotide sequence of leuA from Salmonella typhimurium
  JOURNAL   Nucleic Acids Res. 18, 1290 (1990)
REFERENCE   57
  AUTHORS   Honore,N. and Cole,S.T.
  TITLE     Nucleotide sequence of the aroP gene encoding the general aromatic
            amino acid transport protein of Escherichia coli K-12: homology
            with yeast transport proteins
  JOURNAL   Nucleic Acids Res. 18, 653 (1990)
REFERENCE   58
  AUTHORS   Angerer,A., Gaisser,S. and Braun,V.
  TITLE     Nucleotide sequences of the sfuA, sfuB, and sfuC genes of Serratia
            marcescens suggest a periplasmic-binding-protein-dependent iron
            transport mechanism
  JOURNAL   J. Bacteriol. 172, 572-578 (1990)
REFERENCE   59
  AUTHORS   Surin,B.P., Watson,J.M., Hamilton,W.D., Economou,A. and Downie,J.A.
  TITLE     Molecular characterization of the nodulation gene, nodT, from two
            biovars of Rhizobium leguminosarum
  JOURNAL   Mol. Microbiol. 4, 245-252 (1990)
REFERENCE   60
  AUTHORS   Zhou,Z. and Syvanen,M.
  TITLE     Identification and sequence of the drpA gene from Escherichia coli
  JOURNAL   J. Bacteriol. 172, 281-286 (1990)
REFERENCE   61
  AUTHORS   Roncero,M.I., Jepsen,L.P., Stroman,P. and van Heeswijck,R.
  TITLE     Characterization of a leuA gene and an ARS element from Mucor
            circinelloides
  JOURNAL   Gene 84, 335-343 (1989)
REFERENCE   62
  AUTHORS   Ichikawa,S. and Kaji,A.
  TITLE     Molecular cloning and expression of ribosome releasing factor
  JOURNAL   J. Biol. Chem. 264, 20054-20059 (1989)
REFERENCE   63
  AUTHORS   Minami-Ishii,N., Taketani,S., Osumi,T. and Hashimoto,T.
  TITLE     Molecular cloning and sequence analysis of the cDNA for rat
            mitochondrial enoyl-CoA hydratase. Structural and evolutionary
            relationships linked to the bifunctional enzyme of the peroxisomal
            beta-oxidation system
  JOURNAL   Eur. J. Biochem. 185, 73-78 (1989)
REFERENCE   64
  AUTHORS   Matsubara,Y., Indo,Y., Naito,E., Ozasa,H., Glassberg,R.,
            Vockley,J., Ikeda,Y., Kraus,J. and Tanaka,K.
  TITLE     Molecular cloning and nucleotide sequence of cDNAs encoding the
            precursors of rat long chain acyl-coenzyme A, short chain
            acyl-coenzyme A, and isovaleryl-coenzyme A dehydrogenases.
            Sequence homology of four enzymes of the acyl-CoA dehydrogenase
            family
  JOURNAL   J. Biol. Chem. 264, 16321-16331 (1989)
REFERENCE   65
  AUTHORS   Roa,B.B., Connolly,D.M. and Winkler,M.E.
  TITLE     Overlap between pdxA and ksgA in the complex pdxA-ksgA-apaG-apaH
            operon of Escherichia coli K-12
  JOURNAL   J. Bacteriol. 171, 4767-4777 (1989)
REFERENCE   66
  AUTHORS   Xie,Q.W., Tabor,C.W. and Tabor,H.
  TITLE     Spermidine biosynthesis in Escherichia coli: promoter and
            termination regions of the speED operon
  JOURNAL   J. Bacteriol. 171, 4457-4465 (1989)
REFERENCE   67
  AUTHORS   Lindquist,S., Galleni,M., Lindberg,F. and Normark,S.
  TITLE     Signalling proteins in enterobacterial AmpC beta-lactamase
            regulation
  JOURNAL   Mol. Microbiol. 3, 1091-1102 (1989)
REFERENCE   68
  AUTHORS   Sato,S., Nakada,Y. and Shiratsuchi,A.
  TITLE     IS421, a new insertion sequence in Escherichia coli
  JOURNAL   FEBS Lett. 249, 21-26 (1989)
REFERENCE   69
  AUTHORS   Liu,J.D. and Parkinson,J.S.
  TITLE     Genetics and sequence analysis of the pcnB locus, an Escherichia
            coli gene involved in plasmid copy number control
  JOURNAL   J. Bacteriol. 171, 1254-1261 (1988)
REFERENCE   70
  AUTHORS   Henrich,B., Schroeder,U., Frank,R.W. and Plapp,R.
  TITLE     Accurate mapping of the Escherichia coli pepD gene by sequence
            analysis of its 5' flanking region
  JOURNAL   Mol. Gen. Genet. 215, 369-373 (1989)
REFERENCE   71
  AUTHORS   Lipinska,B., Sharma,S. and Georgopoulos,C.
  TITLE     Sequence analysis and regulation of the htrA gene of Escherichia
            coli: a sigma 32-independent mechanism of heat-inducible
            transcription
  JOURNAL   Nucleic Acids Res. 16, 10053-10067 (1988)
REFERENCE   72
  AUTHORS   Sung,Y.C. and Fuchs,J.A.
  TITLE     Characterization of the cyn operon in Escherichia coli K12
  JOURNAL   J. Biol. Chem. 263, 14769-14775 (1988)
REFERENCE   73
  AUTHORS   Andrews,S.C. and Guest,J.R.
  TITLE     Nucleotide sequence of the gene encoding the GMP reductase of
            Escherichia coli K12
  JOURNAL   Biochem. J. 255, 35-43 (1988)
REFERENCE   74
  AUTHORS   Lozoya,E., Hoffmann,H., Douglas,C., Schulz,W., Scheel,D. and
            Hahlbrock,K.
  TITLE     Primary structures and catalytic properties of isoenzymes encoded
            by the two 4-coumarate: CoA ligase genes in parsley
  JOURNAL   Eur. J. Biochem. 176, 661-667 (1988)
REFERENCE   75
  AUTHORS   Jaiswal,A.K., McBride,O.W., Adesnik,M. and Nebert,D.W.
  TITLE     Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase.
            cDNA sequence and localization of gene to chromosome 16
  JOURNAL   J. Biol. Chem. 263, 13572-13578 (1988)
REFERENCE   76
  AUTHORS   Karpel,R., Olami,Y., Taglicht,D., Schuldiner,S. and Padan,E.
  TITLE     Sequencing of the gene ant which affects the Na+/H+ antiporter
            activity in Escherichia coli
  JOURNAL   J. Biol. Chem. 263, 10408-10414 (1988)
REFERENCE   77
  AUTHORS   Mellano,M.A. and Cooksey,D.A.
  TITLE     Nucleotide sequence and organization of copper resistance genes
            from Pseudomonas syringae pv. tomato
  JOURNAL   J. Bacteriol. 170, 2879-2883 (1988)
REFERENCE   78
  AUTHORS   Coleman,J. and Raetz,C.R.
  TITLE     First committed step of lipid A biosynthesis in Escherichia coli:
            sequence of the lpxA gene
  JOURNAL   J. Bacteriol. 170, 1268-1274 (1988)
REFERENCE   79
  AUTHORS   Gebhard,W., Schreitmuller,T., Hochstrasser,K. and Wachter,E.
  TITLE     Complementary DNA and derived amino acid sequence of the precursor
            of one of the three protein components of the inter-alpha-trypsin
            inhibitor complex
  JOURNAL   FEBS Lett. 229, 63-67 (1988)
REFERENCE   80
  AUTHORS   Tomasiewicz,H.G. and McHenry,C.S.
  TITLE     Sequence analysis of the Escherichia coli dnaE gene
  JOURNAL   J. Bacteriol. 169, 5735-5744 (1987)
REFERENCE   81
  AUTHORS   Crowell,D.N., Reznikoff,W.S. and Raetz,C.R.
  TITLE     Nucleotide sequence of the Escherichia coli gene for lipid A
            disaccharide synthase
  JOURNAL   J. Bacteriol. 169, 5727-5734 (1987)
REFERENCE   82
  AUTHORS   Tabor,C.W. and Tabor,H.
  TITLE     The speEspeD operon of Escherichia coli. Formation and processing
            of a proenzyme form of S-adenosylmethionine decarboxylase
  JOURNAL   J. Biol. Chem. 262, 16037-16040 (1987)
REFERENCE   83
  AUTHORS   Nonet,M.L., Marvel,C.C. and Tolan,D.R.
  TITLE     The hisT-purF region of the Escherichia coli K-12 chromosome.
            Identification of additional genes of the hisT and purF operons
  JOURNAL   J. Biol. Chem. 262, 12209-12217 (1987)
REFERENCE   84
  AUTHORS   Coulton,J.W., Mason,P. and Allatt,D.D.
  TITLE     fhuC and fhuD genes for iron (III)-ferrichrome transport into
            Escherichia coli K-12
  JOURNAL   J. Bacteriol. 169, 3844-3849 (1987)
REFERENCE   85
  AUTHORS   Ben-Bassat,A., Bauer,K., Chang,S.Y., Myambo,K., Boosman,A. and
            Chang,S.
  TITLE     Processing of the initiation methionine from proteins: properties
            of the Escherichia coli methionine aminopeptidase and its gene
            structure
  JOURNAL   J. Bacteriol. 169, 751-757 (1987)
REFERENCE   86
  AUTHORS   Horiuchi,T., Nagasawa,T., Takano,K. and Sekiguchi,M.
  TITLE     A newly discovered tRNA(1Asp) gene (aspV) of Escherichia coli K12
  JOURNAL   Mol. Gen. Genet. 206, 356-357 (1987)
REFERENCE   87
  AUTHORS   Gronger,P., Manian,S.S., Reilander,H., O'Connell,M., Priefer,U.B.
            and Puhler,A.
  TITLE     Organization and partial sequence of a DNA region of the Rhizobium
            leguminosarum symbiotic plasmid pRL6JI containing the genes
            fixABC, nifA, nifB and a novel open reading frame
  JOURNAL   Nucleic Acids Res. 15, 31-49 (1987)
REFERENCE   88
  AUTHORS   Chye,M.L. and Pittard,J.
  TITLE     Transcription control of the aroP gene in Escherichia coli K-12:
            analysis of operator mutants
  JOURNAL   J. Bacteriol. 169, 386-393 (1987)
REFERENCE   89
  AUTHORS   Richardson,K.K., Richardson,F.C., Crosby,R.M., Swenberg,J.A. and
            Skopek,T.R.
  TITLE     DNA base changes and alkylation following in vivo exposure of
            Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 84, 344-348 (1987)
REFERENCE   90
  AUTHORS   Blanchin-Roland,S., Blanquet,S., Schmitter,J.M. and Fayat,G.
  TITLE     The gene for Escherichia coli diadenosine tetraphosphatase is
            located immediately clockwise to folA and forms an operon with ksgA
  JOURNAL   Mol. Gen. Genet. 205, 515-522 (1986)
REFERENCE   91
  AUTHORS   Takano,K., Nakabeppu,Y., Maki,H., Horiuchi,T. and Sekiguchi,M.
  TITLE     Structure and function of dnaQ and mutD mutators of Escherichia
            coli
  JOURNAL   Mol. Gen. Genet. 205, 9-13 (1986)
REFERENCE   92
  AUTHORS   Mackie,G.A.
  TITLE     Structure of the DNA distal to the gene for ribosomal protein S20
            in Escherichia coli K12: presence of a strong terminator and an
            IS1 element
  JOURNAL   Nucleic Acids Res. 14, 6965-6981 (1986)
REFERENCE   93
  AUTHORS   Koster,W. and Braun,V.
  TITLE     Iron hydroxamate transport of Escherichia coli: nucleotide
            sequence of the fhuB gene and identification of the protein
  JOURNAL   Mol. Gen. Genet. 204, 435-442 (1986)
REFERENCE   94
  AUTHORS   Breton,R., Sanfacon,H., Papayannopoulos,I., Biemann,K. and
            Lapointe,J.
  TITLE     Glutamyl-tRNA synthetase of Escherichia coli. Isolation and
            primary structure of the gltX gene and homology with other
            aminoacyl-tRNA synthetases
  JOURNAL   J. Biol. Chem. 261, 10610-10617 (1986)
REFERENCE   95
  AUTHORS   Birnbaum,M.J., Haspel,H.C. and Rosen,O.M.
  TITLE     Cloning and characterization of a cDNA encoding the rat brain
            glucose-transporter protein
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 83, 5784-5788 (1986)
REFERENCE   96
  AUTHORS   Cox,E.C. and Horner,D.L.
  TITLE     DNA sequence and coding properties of mutD(dnaQ) a dominant
            Escherichia coli mutator gene
  JOURNAL   J. Mol. Biol. 190, 113-117 (1986)
REFERENCE   97
  AUTHORS   Sekiguchi,T., Ortega-Cesena,J., Nosoh,Y., Ohashi,S., Tsuda,K. and
            Kanaya,S.
  TITLE     DNA and amino-acid sequences of 3-isopropylmalate dehydrogenase of
            Bacillus coagulans. Comparison with the enzymes of Saccharomyces
            cerevisiae and Thermus thermophilus
  JOURNAL   Biochim. Biophys. Acta 867, 36-44 (1986)
REFERENCE   98
  AUTHORS   Ohki,M., Tamura,F., Nishimura,S. and Uchida,H.
  TITLE     Nucleotide sequence of the Escherichia coli dnaJ gene and
            purification of the gene product
  JOURNAL   J. Biol. Chem. 261, 1778-1781 (1986)
REFERENCE   99
  AUTHORS   Lee,N., Gielow,W., Martin,R., Hamilton,E. and Fowler,A.
  TITLE     The organization of the araBAD operon of Escherichia coli
  JOURNAL   Gene 47, 231-244 (1986)
REFERENCE   100
  AUTHORS   Coulton,J.W., Mason,P., Cameron,D.R., Carmel,G., Jean,R. and
            Rode,H.N.
  TITLE     Protein fusions of beta-galactosidase to the ferrichrome-iron
            receptor of Escherichia coli K-12
  JOURNAL   J. Bacteriol. 165, 181-192 (1986)
REFERENCE   101
  AUTHORS   Chong,P., Hui,I., Loo,T. and Gillam,S.
  TITLE     Structural analysis of a new GC-specific insertion element IS186
  JOURNAL   FEBS Lett. 192, 47-52 (1985)
REFERENCE   102
  AUTHORS   Icho,T., Sparrow,C.P. and Raetz,C.R.
  TITLE     Molecular cloning and sequencing of the gene for CDP-diglyceride
            synthetase of Escherichia coli
  JOURNAL   J. Biol. Chem. 260, 12078-12083 (1985)
REFERENCE   103
  AUTHORS   Nomura,T., Aiba,H. and Ishihama,A.
  TITLE     Transcriptional organization of the convergent overlapping
            dnaQ-rnh genes of Escherichia coli
  JOURNAL   J. Biol. Chem. 260, 7122-7125 (1985)
REFERENCE   104
  AUTHORS   Kamio,Y., Lin,C.K., Regue,M. and Wu,H.C.
  TITLE     Characterization of the ileS-lsp operon in Escherichia coli.
            Identification of an open reading frame upstream of the ileS gene
            and potential promoter(s) for the ileS-lsp operon
  JOURNAL   J. Biol. Chem. 260, 5616-5620 (1985)
REFERENCE   105
  AUTHORS   Cowing,D.W., Bardwell,J.C., Craig,E.A., Woolford,C., Hendrix,R.W.
            and Gross,C.A.
  TITLE     Consensus sequence for Escherichia coli heat shock gene promoters
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 82, 2679-2683 (1985)
REFERENCE   106
  AUTHORS   Broome-Smith,J.K., Edelman,A., Yousif,S. and Spratt,B.G.
  TITLE     The nucleotide sequences of the ponA and ponB genes encoding
            penicillin-binding protein 1A and 1B of Escherichia coli K12
  JOURNAL   Eur. J. Biochem. 147, 437-446 (1985)
REFERENCE   107
  AUTHORS   Becerril,B., Valle,F., Merino,E., Riba,L. and Bolivar,F.
  TITLE     Repetitive extragenic palindromic (REP) sequences in the
            Escherichia coli gdhA gene
  JOURNAL   Gene 37, 53-62 (1985)
REFERENCE   108
  AUTHORS   Friedberg,D., Rosenthal,E.R., Jones,J.W. and Calvo,J.M.
  TITLE     Characterization of the 3' end of the leucine operon of Salmonella
            typhimurium
  JOURNAL   Mol. Gen. Genet. 199, 486-494 (1985)
REFERENCE   109
  AUTHORS   Bouvier,J., Richaud,C., Richaud,F., Patte,J.C. and Stragier,P.
  TITLE     Nucleotide sequence and expression of the Escherichia coli dapB
            gene
  JOURNAL   J. Biol. Chem. 259, 14829-14834 (1984)
REFERENCE   110
  AUTHORS   Richaud,C., Richaud,F., Martin,C., Haziza,C. and Patte,J.C.
  TITLE     Regulation of expression and nucleotide sequence of the
            Escherichia coli dapD gene
  JOURNAL   J. Biol. Chem. 259, 14824-14828 (1984)
REFERENCE   111
  AUTHORS   Nuesch,J. and Schumperli,D.
  TITLE     Structural and functional organization of the gpt gene region of
            Escherichia coli
  JOURNAL   Gene 32, 243-249 (1984)
REFERENCE   112
  AUTHORS   Jagadeeswaran,P., Ashman,C.R., Roberts,S. and Langenberg,J.
  TITLE     Nucleotide sequence and analysis of deletion mutants of the
            Escherichia coli gpt gene in plasmid pSV2 gpt
  JOURNAL   Gene 31, 309-313 (1984)
REFERENCE   113
  AUTHORS   Deutch,A.H., Rushlow,K.E. and Smith,C.J.
  TITLE     Analysis of the Escherichia coli proBA locus by DNA and protein
            sequencing
  JOURNAL   Nucleic Acids Res. 12, 6337-6355 (1984)
REFERENCE   114
  AUTHORS   Bouvier,J., Patte,J.C. and Stragier,P.
  TITLE     Multiple regulatory signals in the control region of the
            Escherichia coli carAB operon
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 81, 4139-4143 (1984)
REFERENCE   115
  AUTHORS   Innis,M.A., Tokunaga,M., Williams,M.E., Loranger,J.M., Chang,S.Y.,
            Chang,S. and Wu,H.C.
  TITLE     Nucleotide sequence of the Escherichia coli prolipoprotein signal
            peptidase (lsp) gene
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 81, 3708-3712 (1984)
REFERENCE   116
  AUTHORS   Bardwell,J.C. and Craig,E.A.
  TITLE     Major heat shock gene of Drosophila and the Escherichia coli
            heat-inducible dnaK gene are homologous
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 81, 848-852 (1984)
REFERENCE   117
  AUTHORS   Pratt,D. and Subramani,S.
  TITLE     Nucleotide sequence of the Escherichia coli xanthine-guanine
            phosphoribosyl transferase gene
  JOURNAL   Nucleic Acids Res. 11, 8817-8823 (1983)
REFERENCE   118
  AUTHORS   Richardson,K.K., Fostel,J. and Skopek,T.R.
  TITLE     Nucleotide sequence of the xanthine guanine phosphoribosyl
            transferase gene of E. coli
  JOURNAL   Nucleic Acids Res. 11, 8809-8816 (1983)
REFERENCE   119
  AUTHORS   Parsot,C., Cossart,P., Saint-Girons,I. and Cohen,G.N.
  TITLE     Nucleotide sequence of thrC and of the transcription termination
            region of the threonine operon in Escherichia coli K12
  JOURNAL   Nucleic Acids Res. 11, 7331-7345 (1983)
REFERENCE   120
  AUTHORS   Stephens,P.E., Lewis,H.M., Darlison,M.G. and Guest,J.R.
  TITLE     Nucleotide sequence of the lipoamide dehydrogenase gene of
            Escherichia coli K12
  JOURNAL   Eur. J. Biochem. 135, 519-527 (1983)
REFERENCE   121
  AUTHORS   Stephens,P.E., Darlison,M.G., Lewis,H.M. and Guest,J.R.
  TITLE     The pyruvate dehydrogenase complex of Escherichia coli K12.
            Nucleotide sequence encoding the dihydrolipoamide
            acetyltransferase component
  JOURNAL   Eur. J. Biochem. 133, 481-489 (1983)
REFERENCE   122
  AUTHORS   Stephens,P.E., Darlison,M.G., Lewis,H.M. and Guest,J.R.
  TITLE     The pyruvate dehydrogenase complex of Escherichia coli K12.
            Nucleotide sequence encoding the pyruvate dehydrogenase component
  JOURNAL   Eur. J. Biochem. 133, 155-162 (1983)
REFERENCE   123
  AUTHORS   Kanaya,S. and Crouch,R.J.
  TITLE     Low levels of RNase H activity in Escherichia coli FB2 rnh result
            from a single-base change in the structural gene of RNase H
  JOURNAL   J. Bacteriol. 154, 1021-1026 (1983)
REFERENCE   124
  AUTHORS   Overbeeke,N., Bergmans,H., van Mansfeld,F. and Lugtenberg,B.
  TITLE     Complete nucleotide sequence of phoE, the structural gene for the
            phosphate limitation inducible outer membrane pore protein of
            Escherichia coli K12
  JOURNAL   J. Mol. Biol. 163, 513-532 (1983)
REFERENCE   125
  AUTHORS   Gilson,E., Nikaido,H. and Hofnung,M.
  TITLE     Sequence of the malK gene in E.coli K12
  JOURNAL   Nucleic Acids Res. 10, 7449-7458 (1982)
REFERENCE   126
  AUTHORS   Stoner,C.M. and Schleif,R.
  TITLE     Is the amino acid but not the nucleotide sequence of the
            Escherichia coli araC gene conserved?
  JOURNAL   J. Mol. Biol. 154, 649-652 (1982)
REFERENCE   127
  AUTHORS   An,G., Bendiak,D.S., Mamelak,L.A. and Friesen,J.D.
  TITLE     Organization and nucleotide sequence of a new ribosomal operon in
            Escherichia coli containing the genes for ribosomal protein S2 and
            elongation factor Ts
  JOURNAL   Nucleic Acids Res. 9, 4163-4172 (1981)
REFERENCE   128
  AUTHORS   Mackie,G.A.
  TITLE     Nucleotide sequence of the gene for ribosomal protein S20 and its
            flanking regions
  JOURNAL   J. Biol. Chem. 256, 8177-8182 (1981)
REFERENCE   129
  AUTHORS   Little,J.W., Mount,D.W. and Yanisch-Perron,C.R.
  TITLE     Purified lexA protein is a repressor of the recA and lexA genes
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 78, 4199-4203 (1981)
REFERENCE   130
  AUTHORS   Mulligan,R.C. and Berg,P.
  TITLE     Factors governing the expression of a bacterial gene in mammalian
            cells
  JOURNAL   Mol. Cell. Biol. 1, 449-459 (1981)
REFERENCE   131
  AUTHORS   Lee,N.L., Gielow,W.O. and Wallace,R.G.
  TITLE     Mechanism of araC autoregulation and the domains of two
            overlapping promoters, Pc and PBAD, in the L-arabinose regulatory
            region of Escherichia coli
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 78, 752-756 (1981)
REFERENCE   132
  AUTHORS   Cossart,P., Katinka,M. and Yaniv,M.
  TITLE     Nucleotide sequence of the thrB gene of E. coli, and its two
            adjacent regions; the thrAB and thrBC junctions
  JOURNAL   Nucleic Acids Res. 9, 339-347 (1981)
REFERENCE   133
  AUTHORS   Miyada,C.G., Horwitz,A.H., Cass,L.G., Timko,J. and Wilcox,G.
  TITLE     DNA sequence of the araC regulatory gene from Escherichia coli B/r
  JOURNAL   Nucleic Acids Res. 8, 5267-5274 (1980)
REFERENCE   134
  AUTHORS   Katinka,M., Cossart,P., Sibilli,L., Saint-Girons,I.,
            Chalvignac,M.A., Le Bras,G., Cohen,G.N. and Yaniv,M.
  TITLE     Nucleotide sequence of the thrA gene of Escherichia coli
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 77, 5730-5733 (1980)
REFERENCE   135
  AUTHORS   Ogden,S., Haggerty,D., Stoner,C.M., Kolodrubetz,D. and Schleif,R.
  TITLE     The Escherichia coli L-arabinose operon: binding sites of the
            regulatory proteins and a mechanism of positive and negative
            regulation
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 77, 3346-3350 (1980)
REFERENCE   136
  AUTHORS   Smith,D.R. and Calvo,J.M.
  TITLE     Nucleotide sequence of the E. coli gene coding for dihydrofolate
            reductase
  JOURNAL   Nucleic Acids Res. 8, 2255-2274 (1980)
REFERENCE   137
  AUTHORS   Johnsrud,L.
  TITLE     DNA sequence of the transposable element IS1
  JOURNAL   Mol. Gen. Genet. 169, 213-218 (1979)
REFERENCE   138
  AUTHORS   Smith,B.R. and Schleif,R.
  TITLE     Nucleotide sequence of the L-arabinose regulatory region of
            Escherichia coli K12
  JOURNAL   J. Biol. Chem. 253, 6931-6933 (1978)
REFERENCE   139
  AUTHORS   Greenfield,L., Boone,T. and Wilcox,G.
  TITLE     DNA sequence of the araBAD promoter in Escherichia coli B/r
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 75, 4724-4728 (1978)
REFERENCE   140
  AUTHORS   Young,R.A. and Steitz,J.A.
  TITLE     Complementary sequences 1700 nucleotides apart form a ribonuclease
            III cleavage site in Escherichia coli ribosomal precursor RNA
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 75, 3593-3597 (1978)
REFERENCE   141
  AUTHORS   Ohtsubo,H. and Ohtsubo,E.
  TITLE     Nucleotide sequence of an insertion element, IS1
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 75, 615-619 (1978)
REFERENCE   142
  AUTHORS   Musso,R., Di Lauro,R., Rosenberg,M. and de Crombrugghe,B.
  TITLE     Nucleotide sequence of the operator-promoter region of the
            galactose operon of Escherichia coli
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 74, 106-110 (1977)
COMMENT     
FEATURES             Qualifiers
     source          /db_xref="taxon:316407"
                     /mol_type="genomic DNA"
                     /organism="Escherichia coli str. K-12 substr. W3110"
                     /strain="K12"
                     /sub_strain="W3110"
     protein         /gene="ileS"
                     /note="ECK0027:JW0024:b0026"
                     /transl_table=11
BEGIN
        1 MSDYKSTLNL PETGFPMRGD LAKREPGMLA RWTDDDLYGI IRAAKKGKKT FILHDGPPYA
       61 NGSIHIGHSV NKILKDIIVK SKGLSGYDSP YVPGWDCHGL PIELKVEQEY GKPGEKFTAA
      121 EFRAKCREYA ATQVDGQRKD FIRLGVLGDW SHPYLTMDFK TEANIIRALG KIIGNGHLHK
      181 GAKPVHWCVD CRSALAEAEV EYYDKTSPSI DVAFQAVDQD ALKAKFAVSN VNGPISLVIW
      241 TTTPWTLPAN RAISIAPDFD YALVQIDGQA VILAKDLVES VMQRIGVTDY TILGTVKGAE
      301 LELLRFTHPF MGFDVPAILG DHVTLDAGTG AVHTAPGHGP DDYVIGQKYG LETANPVGPD
      361 GTYLPGTYPT LDGVNVFKAN DIVVALLQEK GALLHVEKMQ HSYPCCWRHK TPIIFRATPQ
      421 WFVSMDQKGL RAQSLKEIKG VQWIPDWGQA RIESMVANRP DWCISRQRTW GVPMSLFVHK
      481 DTEELHPRTL ELMEEVAKRV EVDGIQAWWD LDAKEILGDE ADQYVKVPDT LDVWFDSGST
      541 HSSVVDVRPE FAGHAADMYL EGSDQHRGWF MSSLMISTAM KGKAPYRQVL THGFTVDGQG
      601 RKMSKSIGNT VSPQDVMNKL GADILRLWVA STDYTGEMAV SDEILKRAAD SYRRIRNTAR
      661 FLLANLNGFD PAKDMVKPEE MVVLDRWAVG CAKAAQEDIL KAYEAYDFHE VVQRLMRFCS
      721 VEMGSFYLDI IKDRQYTAKA DSVARRSCQT ALYHIAEALV RWMAPILSFT ADEVWGYLPG
      781 EREKYVFTGE WYEGLFGLAD SEAMNDAFWD ELLKVRGEVN KVIEQARADK KVGGSLEAAV
      841 TLYAEPELSA KLTALGDELR FVLLTSGATV ADYNDAPADA QQSEVLKGLK VALSKAEGEK
      901 CPRCWHYTQD VGKVAEHAEI CGRCVSNVAG DGEKRKFA
//