LOCUS BAB70696.1 3657 aa PRT HUM 27-OCT-2001
DEFINITION Homo sapiens phosphatidylinositol 3-kinase-related protein
kinase protein.
ACCESSION AB061371-1
PROTEIN_ID BAB70696.1
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 13110)
AUTHORS Ohno,S.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2001) to the DDBJ/EMBL/GenBank databases.
Contact:Shigeo Ohno
Yokohama City University School of Medicine, Department of
Molecular Biology; 3-9, Fuku-ura, Kanazawa-ku, Yokohama City,
Kanagawa-ken 236-0004, Japan
REFERENCE 2
AUTHORS Yamashita,A., Ohnishi,T., Kashima,I., Taya,Y. and Ohno,S.
TITLE Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein
kinase, associates with components of the mRNA surveillance
complex and is involved in the regulation of nonsense-mediated
mRNA decay
JOURNAL Genes Dev. 15, 2215-2228 (2001)
COMMENT
FEATURES Qualifiers
source /chromosome="16"
/country="Japan:Kanagawa, Yokohama, Kanazawa"
/db_xref="H-InvDB:HIT000059838"
/db_xref="taxon:9606"
/map="16p12"
/mol_type="mRNA"
/organism="Homo sapiens"
protein /gene="smg-1"
/note="hSMG-1"
/transl_table=1
BEGIN
1 MSRRAPGSRL SSGGTNYSRS WNDWQPRTDS ASADPGNLKY SSSRDRGGSS SYGLQPSNSA
61 VVSRQRHDDT RVHADIQNDE KGGYSVNGGS GENTYGRKSL GQELRVNNVT SPEFTSVQHG
121 SRALATKDMR KSQERSMSYS DESRLSNLLR RITREDDRDR RLATVKQLKE FIQQPENKLV
181 LVKQLDNILA AVHDVLNESS KLLQELRQEG ACCLGLLCAS LSYEAEKIFK WIFSKFSSSA
241 KDEVKLLYLC ATYKALETVG EKKAFSSVMQ LVMTSLQSIL ENVDTPELLC KCVKCILLVA
301 RCYPHIFSTN FRDTVDILVG WHIDHTQKPS LTQQVSGWLQ SLEPFWVADL AFSTTLLGQF
361 LEDMEAYAED LSHVASGESV DEDVPPPSVS LPKLAALLRV FSTVVRSIGE RFSPIRGPPI
421 TEAYVTDVLY RVMRCVTAAN QVFFSEAVLT AANECVGVLL GSLDPSMTIH CDMVITYGLD
481 QLENCQTCGT DYIISVLNLL TLIVEQINTK LPSSFVEKLF IPSSKLLFLR YHKEKEVVAV
541 AHAVYQAVLS LKNIPVLETA YKLILGEMTC ALNNLLHSLQ LPEACSEIKH EAFKNHVFNV
601 DNAKFVVKFD LSALTTIGNA KNSLIGMWAL SPTVFALLSK NLMIVHSDLA VHFPAIQYAV
661 LYTLYSHCTR HDHFISSSLS SASPSLFDGA VISTVTTATK KHFSIILNLL GILLKKDNLN
721 QDTRKLLMTW ALEAAVLMRK SETYAPLFSL PSFHKFCKGL LANTLVEDVN ICLQACSSLH
781 ALSSSLPDDL LQRCVDVCRV QLVHSGTRIR QAFGKLLKSI PLDVVLSNNN HTEIQEISLA
841 LRSHMSKAPS NTFHPQDFSD VISFILYGNS HRTGKDNWLE RLFYSCQRLD KRDQSTIPRN
901 LLKTDAVLWQ WAIWEAAQFT VLSKLRTPLG RAQDTFQTIE GIIRSLAAHT LNPDQDVSQW
961 TTADNDEGHG NNQLRLVLLL QYLENLEKLM YNAYEGCANA LTSPPKVIRT FFYTNRQTCQ
1021 DWLTRIRLSI MRVGLLAGQP AVTVRHGFDL LTEMKTTSLS QGNELEVTIM MVVEALCELH
1081 CPEAIQGIAV WSSSIVGKNL LWINSVAQQA EGRFEKASVE YQEHLCAMTG VDCCISSFDK
1141 SVLTLANAGR NSASPKHSLN GESRKTVLSK PTDSSPEVIN YLGNKACEFY ISIADWAAVQ
1201 EWQNAIHDLK KSTSSTSLNL KADFNYIKSL SSFESGKFVE CTEQLELLPG ENINLLAGGS
1261 KEKIDMKKLL PNMLSPDPRE LQKSIEVQLL RSSVCLATAL NPIEQDQKWQ SITENVVKYL
1321 KQTSRIAIGP LRLSTLTVSQ SLPVLSTLQL YCSSALENTV SNRLSTEDCL IPLFSEALRS
1381 CKQHDVRPWM QALRYTMYQN QLLEKIKEQT VPIRSHLMEL GLTAAKFARK RGNVSLATRL
1441 LAQCSEVQLG KTTTAQDLVQ HFKKLSTQGQ VDEKWGPELD IEKTKLLYTA GQSTHAMEML
1501 SSCAISFCKS VKAEYAVAKS ILTLAKWIQA EWKEISGQLK QVYRAQHQQN FTGLSTLSKN
1561 ILTLIELPSV NTMEEEYPRI ESESTVHIGV GEPDFILGQL YHLSSVQAPE VAKSWAALAS
1621 WAYRWGRKVV DNASQGEGVR LLPREKSEVQ NLLPDTITEE EKERIYGILG QAVCRPAGIQ
1681 DEDITLQITE SEDNEEDDMV DVIWRQLISS CPWLSELDES ATEGVIKVWR KVVDRIFSLY
1741 KLSCSAYFTF LKLNAGQIPL DEDDPRLHLS HRVEQSTDDM IVMATLRLLR LLVKHAGELR
1801 QYLEHGLETT PTAPWRGIIP QLFSRLNHPE VYVRQSICNL LCRVAQDSPH LILYPAIVGT
1861 ISLSSESQAS GNKFSTAIPT LLGNIQGEEL LVSECEGGSP PASQDSNKDE PKSGLNEDQA
1921 MMQDCYSKIV DKLSSANPTM VLQVQMLVAE LRRVTVLWDE LWLGVLLQQH MYVLRRIQQL
1981 EDEVKRVQNN NTLRKEEKIA IMRERHTALM KPIVFALEHV RSITAAPAET PHEKWFQDNY
2041 GDAIENALEK LKTPLNPAKP GSSWIPFKEI MLSLQQRAQK RASYILRLEE ISPWLAAMTN
2101 TEIALPGEVS ARDTVTIHSV GGTITILPTK TKPKKLLFLG SDGKSYPYLF KGLEDLHLDE
2161 RIMQFLSIVN TMFATINRQE TPRFHARHYS VTPLGTRSGL IQWVDGATPL FGLYKRWQQR
2221 EAALQAQKAQ DSYQTPQNPG IVPRPSELYY SKIGPALKTV GLSLDVSRRD WPLHVMKAVL
2281 EELMEATPPN LLAKELWSSC TTPDEWWRVT QSYARSTAVM SMVGYIIGLG DRHLDNVLID
2341 MTTGEVVHID YNVCFEKGKS LRVPEKVPFR MTQNIETALG VTGVEGVFRL SCEQVLHIMR
2401 RGRETLLTLL EAFVYDPLVD WTAGGEAGFA GAVYGGGGQQ AESKQSKREM EREITRSLFS
2461 SRVAEIKVNW FKNRDEMLVV LPKLDGSLDE YLSLQEQLTD VEKLQGKLLE EIEFLEGAEG
2521 VDHPSHTLQH RYSEHTQLQT QQRAVQEAIQ VKLNEFEQWI THYQAAFNNL EATQLASLLQ
2581 EISTQMDLGP PSYVPATAFL QNAGQAHLIS QCEQLEGEVG ALLQQRRSVL RGCLEQLHHY
2641 ATVALQYPKA IFQKHRIEQW KTWMEELICN TTVERCQELY RKYEMQYAPQ PPPTVCQFIT
2701 ATEMTLQRYA ADINSRLIRQ VERLKQEAVT VPVCEDQLKE IERCIKVFLH ENGEEGSLSL
2761 ASVIISALCT LTRRNLMMEG AASSAGEQLV DLTSRDGAWF LEELCSMSGN VTCLVQLLKQ
2821 CHLVPQDLDI PNPMEASETV HLANGVYTSL QELNSNFRQI IFPEALRCLM KGEYTLESML
2881 HELDGLIEQT TDGVPLQTLV ESLQAYLRNA AMGLEEETHA HYIDVARLLH AQYGELIQPR
2941 NGSVDETPKM SAGQMLLVAF DGMFAQVETA FSLLVEKLNK MEIPIAWRKI DIIREARSTQ
3001 VNFFDDDNHR QVLEEIFFLK RLQTIKEFFR LCGTFSKTLS GSSSLEDQNT VNGPVQIVNV
3061 KTLFRNSCFS EDQMAKPIKA FTADFVRQLL IGLPNQALGL TLCSFISALG VDIIAQVEAK
3121 DFGAESKVSV DDLCKKAVEH NIQIGKFSQL VMNRATVLAS SYDTAWKKHD LVRRLETSIS
3181 SCKTSLQRVQ LHIAMFQWQH EDLLINRPQA MSVTPPPRSA ILTSMKKKLH TLSQIETSIA
3241 TVQEKLAALE SSIEQRLKWA GGANPALAPV LQDFEATIAE RRNLVLKESQ RASQVTFLCS
3301 NIIHFESLRT RTAEALNLDA ALFELIKRCQ QMCSFASQFN SSVSELELRL LQRVDTGLEH
3361 PIGSSEWLLS AHKQLTQDMS TQRAIQTEKE QQIETVCETI QNLVDNIKTV LTGHNRQLGD
3421 VKHLLKAMAK DEEAALADGE DVPYENSVRQ FLGEYKSWQD NIQTVLFTLV QAMGQVRSQE
3481 HVEMLQEITP TLKELKTQSQ SIYNNLVSFA SPLVTDATNE CSSPTSSATY QPSFAAAVRS
3541 NTGQKTQPDV MSQNARKLIQ KNLATSADTP PSTVPGTGKS VACSPKKAVR DPKTGKAVQE
3601 RNSYAVSVWK RVKAKLEGRD VDPNRRMSVA EQVDYVIKEA TNLDNLAQLY EGWTAWV
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