LOCUS BAA80874.1 421 aa PRT BCT 07-OCT-2016 DEFINITION Aeropyrum pernix K1 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein. ACCESSION BA000002-1225 PROTEIN_ID BAA80874.1 SOURCE Aeropyrum pernix K1 ORGANISM Aeropyrum pernix K1 Archaea; Thermoproteota; Thermoprotei; Desulfurococcales; Desulfurococcaceae; Aeropyrum. REFERENCE 1 (bases 1 to 1669696) AUTHORS Tanaka,T., Hino,Y., Kawarabayasi,Y., Kikuchi,H., Tajima,T., Sekigawa,T., Oguchi,A., Yamazaki,S., Tanikawa,S., Fujita,N. and Harayama,S. TITLE Direct Submission JOURNAL Submitted (14-DEC-1998) to the DDBJ/EMBL/GenBank databases. Contact:Director-General of Department of Biotechnology National Institute of Technology and Evaluation (NITE), NITE Genome Analysis Center (NGAC), Department of Biotechnology; 2-49-10 Nishihara, Shibuya-ku, Tokyo 151-0066, Japan URL :http://www.bio.nite.go.jp/ REFERENCE 2 AUTHORS Kawarabayasi,Y., Hino,Y., Horikawa,H., Yamazaki,S., Haikawa,Y., Jin-no,K., Takahashi,M., Sekine,M., Baba,S., Ankai,A., Kosugi,H., Hosoyama,A., Fukui,S., Nagai,Y., Nishijima,K., Nakazawa,H., Takamiya,M., Masuda,S., Funahashi,T., Tanaka,T., Kudoh,Y., Yamazaki,J., Kushida,N., Oguchi,A., Aoki,K., Kubota,K., Nakamura,Y., Nomura,N., Sako,Y. and Kikuchi,H. TITLE Complete Genome Sequence of an Aerobic Hyper-thermophilic Crenarchaeon, Aeropyrum pernix K1. JOURNAL DNA Res. 6, 83-101 (1999) REFERENCE 3 AUTHORS Yamazaki,S., Kikuchi,H. and Kawarabayasi,Y. TITLE Characterization of a Whole Set of tRNA Molecules in an Aerobic Hyper-thermophilic Crenarchaeon, Aeropyrum pernix K1 JOURNAL DNA Res. 12, 403-416 (2005) REFERENCE 4 AUTHORS Yamazaki,S., Yamazaki,J., Nishijima,K., Otsuka,R., Mise,M., Ishikawa,H., Sasaki,K., Tago,S. and Isono,K. TITLE Proteome Analysis of an Aerobic Hyperthermophilic Crenarchaeon, Aeropyrum pernix K1 JOURNAL Mol. Cell Proteomics 5, 811-823 (2006) COMMENT Kawarabayasi, Y. is at National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8566, Japan. Tanaka, T., Hino, Y., Kawarabayasi, Y. and Kikuchi, H. are original submitters. Tajima, T., Sekigawa, T., Oguchi, A., Yamazaki, S., Tanikawa, S., Fujita, N. and Harayama S. submitted a revised version of the genomic sequence with a single bp insertion and the result of reannotation. The genome of A. pernix was completely re-annotated in May 2006. Single nucleotide was inserted at position 941,216. Some ORFs were added or modified according to the result of proteome analysis at NITE (Yamazaki, S. et al., Mol Cell Proteomics. 5, 811-823 (2006)). The detailed process of re-annotation is described in http://www.bio.nite.go.jp/dogan/GeneralFeature?GENOME_ID=ape_G1. All locus tags of A. pernix were replaced to new identifiers by the following rules. 1. Prefix 'APE' or 'APES' was replaced by 'APE_'. 2. ORF numbers were inherited except for those with previous locus tag starting with 'APES'. 3. An alphabetical character like 'a' was added after the ORF number where new ORF was inserted between existing ORFs, including those with previous locus tag starting with 'APES'. 4. Version number like '.1' was added where the start position of existing ORF was changed. Please visit our web site. URL:http://www.bio.nite.go.jp/e/ DOGAN ; Database of the Genomes Analyzed at NITE The database contains genome sequence data, physical maps and the genomic and proteomic data of the microorganisms analyzed. URL:http://www.bio.nite.go.jp/dogan/Top The microbial strain and microbial genomic DNA clones used for the sequencing project are available through the NBRC. URL:http://www.nbrc.nite.go.jp/e/index.html FEATURES Qualifiers source /culture_collection="NBRC:100138" /db_xref="taxon:272557" /focus /mol_type="genomic DNA" /note="strain coidentity: NBRC 100138" /organism="Aeropyrum pernix K1" /strain="K1" source /db_xref="taxon:1032474" /mol_type="genomic DNA" /organism="Aeropyrum pernix ovoid virus 1" /proviral source /db_xref="taxon:1032473" /mol_type="genomic DNA" /organism="Aeropyrum pernix spindle-shaped virus 1" /proviral protein /EC_number="1.1.1.34" /experiment="proteome analysis" /gene="hmgA" /locus_tag="APE_1869" /note="HMG-CoA reductase" /old_locus_tag="APE1869" /transl_table=11 BEGIN 1 MGSSSGQKPR RLEDLVDKLA SGSLSHSRLE KELGNANEAA LVRRLYLERL TGASLSSVAS 61 TILDFQELYG RNIENPIGAV QVPVGVAGPL RINGDYARGD FYIPLATTEG ALVASVNRGA 121 KAITLSGGAR AKVIKDGMTR APLLWTPSVY EAHRLAMWVE DRIEDLRSVV AGVTRHGRLQ 181 HIYPYIIGNL VWLRLSFSTG DAMGMNMVTI SSDRICRYIE ENYDGDAKCI ALSGNMCTDK 241 KPAAINKILG RGKYVVAEAV IKGEVVKNVL KTTPQNINLV NVTKNLLGSA AAGSHSFNAH 301 FANIIAAIFI ATGQDAAQVV ESSMGYTWTE VRGEDLYISV TLPSLEVGTV GGGTRLPTQR 361 ELLALLGVAG GGNPPGSNAL KLAEIIASAV LAGELNLLSA IAAGQLARAH ELLGRGGLKI 421 S //