LOCUS       APA94454.1               342 aa    PRT              BCT 30-JAN-2018
DEFINITION  Nocardia seriolae ATP-dependent helicase hrq1 protein.
ACCESSION   CP017839-363
PROTEIN_ID  APA94454.1
SOURCE      Nocardia seriolae
  ORGANISM  Nocardia seriolae
            Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae;
            Nocardia.
REFERENCE   1  (bases 1 to 8304518)
  AUTHORS   Han,H.-J.
  TITLE     Genome sequence of Nocardia seriolae strain EM150506, isolated from
            Anguila japonica
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8304518)
  AUTHORS   Han,H.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2016) Pathology Research Division, National
            Institute of Fisheries Science, #216, Gijanghaean-ro, Gijang-eup,
            Gijang-gun, Busan 46083, South Korea
COMMENT     DNA/bacteria available from National Institute of Fisheries Science
            (NIFS) in South Korea.
            
            ##Genome-Assembly-Data-START##
            Assembly Method       :: SMRT analysis v. 2.3.0
            Genome Coverage       :: 156x
            Sequencing Technology :: PacBio
            ##Genome-Assembly-Data-END##
FEATURES             Qualifiers
     source          /organism="Nocardia seriolae"
                     /mol_type="genomic DNA"
                     /strain="EM150506"
                     /host="Anguilla japonica"
                     /db_xref="taxon:37332"
                     /country="South Korea"
                     /collection_date="2015-05-06"
     protein         /locus_tag="NS506_00371"
                     /function="ATP-binding; DNA damage; DNA repair;
                     DNA-binding; Helicase; Hydrolase; Nucleotide-binding;
                     Nucleus."
                     /note="Helicase with 3'-5' helicase activity involved in
                     genome stability (PubMed:22064477). Functions in the
                     nucleotide excision repair (NER) pathway and plays a
                     critical role in DNA interstrand cross-link repair
                     (PubMed:22064477). Unwinds relatively long duplex DNA up
                     to 120-bp and requires a long 3'-tail of at least 70
                     nucleotides for efficient unwinding of duplex DNA (By
                     similarity). Shows both processive helicase and DNA strand
                     annealing activities (By similarity). Affects telomere
                     length by a non-catalytic mechanism, probably through
                     inhibiting telomerase by competing with it for ssDNA
                     binding (By similarity); Belongs to the helicase family.
                     HRQ1 subfamily; Contains 1 helicase ATP-binding domain;
                     Contains 1 helicase C-terminal domain"
                     /transl_table=11
                     /db_xref="UniProtKB/Swiss-Prot:O13983"
BEGIN
        1 MLNRVLNGAG SGDPRLTHVT ELPPRAAQVT KWPEWTSPEV IAAVQAAGVA EPWSHQIRAA
       61 ELAAAGRHVV VSTGTASGKS LAYQLPVLTA LQADPRATAL YLSPTKALGA DQLRMVNELT
      121 SEDPLRNVHP APYDGDTPAE IRQWVRAHAR WVFTNPDMLH VGMLRSHQRW ARFFRQLKYV
      181 VVDECHIYRG VFGSHVALVL RRLRRLAARY GADPVFVLCS ATTADPAATA EKLIGAPCVA
      241 VTEDGSPQGA RTVALWEPPL LGAGVTGENG AAVRRSAGAE AATVMADLVA EGARTLTFVR
      301 SRRGAELVAM DTRRLLADVD AELPGRVAAY RAGYLAEDRR AL
//