LOCUS APA94163.1 352 aa PRT BCT 30-JAN-2018 DEFINITION Nocardia seriolae Diacylglycerol O-acyltransferase protein. ACCESSION CP017839-72 PROTEIN_ID APA94163.1 SOURCE Nocardia seriolae ORGANISM Nocardia seriolae Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Nocardia. REFERENCE 1 (bases 1 to 8304518) AUTHORS Han,H.-J. TITLE Genome sequence of Nocardia seriolae strain EM150506, isolated from Anguila japonica JOURNAL Unpublished REFERENCE 2 (bases 1 to 8304518) AUTHORS Han,H.-J. TITLE Direct Submission JOURNAL Submitted (21-OCT-2016) Pathology Research Division, National Institute of Fisheries Science, #216, Gijanghaean-ro, Gijang-eup, Gijang-gun, Busan 46083, South Korea COMMENT DNA/bacteria available from National Institute of Fisheries Science (NIFS) in South Korea. ##Genome-Assembly-Data-START## Assembly Method :: SMRT analysis v. 2.3.0 Genome Coverage :: 156x Sequencing Technology :: PacBio ##Genome-Assembly-Data-END## FEATURES Qualifiers source /organism="Nocardia seriolae" /mol_type="genomic DNA" /strain="EM150506" /host="Anguilla japonica" /db_xref="taxon:37332" /country="South Korea" /collection_date="2015-05-06" protein /locus_tag="NS506_00076" /EC_number="2.3.1.20" /EC_number="2.3.1.122" /function="Acyltransferase; Cell wall; Cytoplasm; Disulfide bond; Secreted; Signal; Transferase." /note="The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M. tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM. FbpA mediates triacylglycerol (TAG) formation with long-chain acyl-CoA as the acyl donor and 1,2-dipalmitoyl-sn-glycerol (1,2-dipalmitin) as the acyl acceptor. It has a preference for C26:0-CoA over C18:1-CoA (By similarity); Belongs to the mycobacterial A85 antigen family; KEGG: mle:ML0097 diacylglycerol O-acyltransferase / trehalose O-mycolyltransferase" /transl_table=11 /db_xref="UniProtKB/Swiss-Prot:O06052" BEGIN 1 MSVRISRITA RLAVAALVSA ASPALGGVPA GADTPTLSGV TVPELKTDDG SYIQNVAARD 61 DHTVTFTVYS AAMNQVFPVD VLRPADTSEA RPTLYLLNGA GGGVDQATWQ LRTDALDFLA 121 DKNVNVVQPI GGAFSWYTDW LSPDKSLGVN KWSTYLGKEL PPLMDAALGT DGVNAIAGIS 181 MAGLPVLNSV IFNPGLFRSA AVYSGFFQTT TPQGRESIKM VTELYGGGKV ENMWGPEGGP 241 LWAANDPTLN AEKLRGTNLF ISTGNGIPGA FDVPGARGRM ERPADTAKAV AIGSFIEANV 301 ELSTFILQKR LESLNIPATF EFRDSGTHIW GYWQDDLKAS WPVLAQGLYS NP //