LOCUS       APA94163.1               352 aa    PRT              BCT 30-JAN-2018
DEFINITION  Nocardia seriolae Diacylglycerol O-acyltransferase protein.
ACCESSION   CP017839-72
PROTEIN_ID  APA94163.1
SOURCE      Nocardia seriolae
  ORGANISM  Nocardia seriolae
            Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae;
            Nocardia.
REFERENCE   1  (bases 1 to 8304518)
  AUTHORS   Han,H.-J.
  TITLE     Genome sequence of Nocardia seriolae strain EM150506, isolated from
            Anguila japonica
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8304518)
  AUTHORS   Han,H.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2016) Pathology Research Division, National
            Institute of Fisheries Science, #216, Gijanghaean-ro, Gijang-eup,
            Gijang-gun, Busan 46083, South Korea
COMMENT     DNA/bacteria available from National Institute of Fisheries Science
            (NIFS) in South Korea.
            
            ##Genome-Assembly-Data-START##
            Assembly Method       :: SMRT analysis v. 2.3.0
            Genome Coverage       :: 156x
            Sequencing Technology :: PacBio
            ##Genome-Assembly-Data-END##
FEATURES             Qualifiers
     source          /organism="Nocardia seriolae"
                     /mol_type="genomic DNA"
                     /strain="EM150506"
                     /host="Anguilla japonica"
                     /db_xref="taxon:37332"
                     /country="South Korea"
                     /collection_date="2015-05-06"
     protein         /locus_tag="NS506_00076"
                     /EC_number="2.3.1.20"
                     /EC_number="2.3.1.122"
                     /function="Acyltransferase; Cell wall; Cytoplasm;
                     Disulfide bond; Secreted; Signal; Transferase."
                     /note="The antigen 85 proteins (FbpA, FbpB, FbpC) are
                     responsible for the high affinity of mycobacteria for
                     fibronectin, a large adhesive glycoprotein, which
                     facilitates the attachment of M. tuberculosis to murine
                     alveolar macrophages (AMs). They also help to maintain the
                     integrity of the cell wall by catalyzing the transfer of
                     mycolic acids to cell wall arabinogalactan, and through
                     the synthesis of alpha,alpha-trehalose dimycolate (TDM,
                     cord factor). They catalyze the transfer of a mycoloyl
                     residue from one molecule of alpha,alpha-trehalose
                     monomycolate (TMM) to another TMM, leading to the
                     formation of TDM. FbpA mediates triacylglycerol (TAG)
                     formation with long-chain acyl-CoA as the acyl donor and
                     1,2-dipalmitoyl-sn-glycerol (1,2-dipalmitin) as the acyl
                     acceptor. It has a preference for C26:0-CoA over C18:1-CoA
                     (By similarity); Belongs to the mycobacterial A85 antigen
                     family; KEGG: mle:ML0097 diacylglycerol O-acyltransferase
                     / trehalose O-mycolyltransferase"
                     /transl_table=11
                     /db_xref="UniProtKB/Swiss-Prot:O06052"
BEGIN
        1 MSVRISRITA RLAVAALVSA ASPALGGVPA GADTPTLSGV TVPELKTDDG SYIQNVAARD
       61 DHTVTFTVYS AAMNQVFPVD VLRPADTSEA RPTLYLLNGA GGGVDQATWQ LRTDALDFLA
      121 DKNVNVVQPI GGAFSWYTDW LSPDKSLGVN KWSTYLGKEL PPLMDAALGT DGVNAIAGIS
      181 MAGLPVLNSV IFNPGLFRSA AVYSGFFQTT TPQGRESIKM VTELYGGGKV ENMWGPEGGP
      241 LWAANDPTLN AEKLRGTNLF ISTGNGIPGA FDVPGARGRM ERPADTAKAV AIGSFIEANV
      301 ELSTFILQKR LESLNIPATF EFRDSGTHIW GYWQDDLKAS WPVLAQGLYS NP
//