LOCUS       AJF01611.1               469 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative integral
            membrane nitrite extrusion protein NarK3 (nitrite facilitator)
            protein.
ACCESSION   CP007027-267
PROTEIN_ID  AJF01611.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="narK3"
                     /locus_tag="Y980_0261c"
                     /note="Rv0261c, (MTCY06A4.05c) Probable nirK3, nitrite
                     extrusion protein, integral membrane protein possibly
                     member of major facilitator superfamily (MFS),equivalent
                     to AAB41700.1|U72744 nitrite extrusion protein from
                     Mycobacterium fortuitum (471 aa); and
                     2342627|CAB11406.1|Z98741|T44908 nitrite extrusion protein
                     homolog from Mycobacterium leprae (517 aa; longer in
                     N-terminus). Also similar to other nitrite extrusion
                     proteins e.g. NARK_ECOLI|P10903|B1223 nitrite extrusion
                     protein 1 from Escherichia coli strain K12 (463 aa).
                     Belongs to the nark/NASA family of transporters."
                     /transl_table=11
                     /db_xref="GOA:L7N5B0"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="UniProtKB/TrEMBL:L7N5B0"
BEGIN
        1 MGRSHQISDW DPEDSVAWEA GNKFIARRNL IWSVAAEHVG FSVWSLWSVM VLFMPTSVYG
       61 FSAGDKFLLG ATATLVGACL RFPYTFATAK FGGRNWTIFS ALVLLIPTVG SILLLANPGL
      121 PLWPYLVCGA LAGLGGGNFA ASMTNINAFF PQRLKGAALA LNAGGGNLGV PMVQLVGLLV
      181 IATAGDREPY WVCAIYLVLL AVAGLGAALY MDNLTEYRIE LNTMRAVVSE PHTWVISLLY
      241 IGTFGSFIGF SFAFGQVLQI NFIASGQSTA QASLHAAQIA FLGPLLGSLS RIYGGKLADR
      301 IGGGRVTLAA FCAMLLATGI LISASTFGDH LAGPMPTATM VGYVIGFTAL FILSGIGNGS
      361 VYKMIPSIFE ARSHSLQISE AERRQWSRSM SGALIGLAGA VGALGGVGVN LALRESYLTS
      421 GTATSAFWAF GVFYLVASVL TWAIYVRRGL KSAGELVPAT TAPAGLAYV
//