LOCUS AJF01537.1 575 aa PRT BCT 20-JUN-2017
DEFINITION Mycobacterium tuberculosis H37RvSiena putative dihydroxy-
acid dehydratase IlvD (dad) protein.
ACCESSION CP007027-193
PROTEIN_ID AJF01537.1
SOURCE Mycobacterium tuberculosis H37RvSiena
ORGANISM Mycobacterium tuberculosis H37RvSiena
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1 (bases 1 to 4410911)
AUTHORS Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
TITLE Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
tuberculosis Reference Strain H37Rv (ATCC27294)
JOURNAL New Microbiol. 40 (1), 62-69 (2017)
PUBMED 27819398
REFERENCE 2 (bases 1 to 4410911)
AUTHORS Guerrini,V., Santoro,F. and Pozzi,G.
TITLE Direct Submission
JOURNAL Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE 3 (bases 1 to 4410911)
AUTHORS Guerrini,V., Santoro,F. and Pozzi,G.
TITLE Direct Submission
JOURNAL Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REMARK Protein update by submitter
COMMENT Annotation was added by the NCBI Prokaryotic Genome Annotation
Pipeline (released 2013). Information about the Pipeline can be
found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
Annotation modified by submitter.
##Assembly-Data-START##
Assembly Method :: Ray v. 2.3.1
Coverage :: 300
Sequencing Technology :: Illumina
##Assembly-Data-END##
##Genome-Annotation-Data-START##
Annotation Provider :: NCBI
Annotation Date :: 12/30/2013 09:28:23
Annotation Pipeline :: NCBI Prokaryotic Genome Annotation
Pipeline
Annotation Method :: Best-placed reference protein set;
GeneMarkS+
Annotation Software revision :: 2.3 (rev. 422554)
Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA;
repeat_region
Genes :: 4,146
CDS :: 4,050
Pseudo Genes :: 42
CRISPR Arrays :: 2
rRNAs :: 3 (5S, 16S, 23S)
tRNAs :: 45
ncRNA :: 6
Frameshifted Genes :: 34
##Genome-Annotation-Data-END##
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37RvSiena"
/mol_type="genomic DNA"
/strain="H37RvSiena"
/db_xref="taxon:1437856"
protein /gene="ilvD"
/locus_tag="Y980_0189c"
/experiment="EXISTENCE: identified in proteomics study"
/inference="protein motif:PROSITE:PS00886"
/note="Rv0189c, (MTCI28.28c) Probable ilvD,dihydroxy-acid
dehydratase, similar to many e.g. ILVD_LACLA|Q02139
dihydroxy-acid dehydratase (dad) from Lactococcus lactis
(subsp. lactis) (Streptococcus lactis) (570 aa). Also
similar to ML2608|MLCL622.06c|O06069|ILVD_MYCLE
dihydroxy-acid dehydratase from Mycobacterium leprae (564
aa). Contains PS00886 Dihydroxy-acid and
6-phosphogluconate dehydratases signature 1. Belongs to
the ILVD / EDD family. Cofactor: binds 1 4FE-4S cluster
(potential)."
/transl_table=11
/db_xref="GOA:P65154"
/db_xref="InterPro:IPR000581"
/db_xref="InterPro:IPR004404"
/db_xref="InterPro:IPR015928"
/db_xref="InterPro:IPR020558"
/db_xref="UniProtKB/Swiss-Prot:P65154"
BEGIN
1 MPQTTDEAAS VSTVADIKPR SRDVTDGLEK AAARGMLRAV GMDDEDFAKP QIGVASSWNE
61 ITPCNLSLDR LANAVKEGVF SAGGYPLEFG TISVSDGISM GHEGMHFSLV SREVIADSVE
121 VVMQAERLDG SVLLAGCDKS LPGMLMAAAR LDLAAVFLYA GSILPGRAKL SDGSERDVTI
181 IDAFEAVGAC SRGLMSRADV DAIERAICPG EGACGGMYTA NTMASAAEAL GMSLPGSAAP
241 PATDRRRDGF ARRSGQAVVE LLRRGITARD ILTKEAFENA IAVVMAFGGS TNAVLHLLAI
301 AHEANVALSL QDFSRIGSGV PHLADVKPFG RHVMSDVDHI GGVPVVMKAL LDAGLLHGDC
361 LTVTGHTMAE NLAAITPPDP DGKVLRALAN PIHPSGGITI LHGSLAPEGA VVKTAGFDSD
421 VFEGTARVFD GERAALDALE DGTITVGDAV VIRYEGPKGG PGMREMLAIT GAIKGAGLGK
481 DVLLLTDGRF SGGTTGLCVG HIAPEAVDGG PIALLRNGDR IRLDVAGRVL DVLADPAEFA
541 SRQQDFSPPP PRYTTGVLSK YVKLVSSAAV GAVCG
//