LOCUS       AJF01521.1               515 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena Mce-family protein
            Mce1F protein.
ACCESSION   CP007027-177
PROTEIN_ID  AJF01521.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="mce1F"
                     /locus_tag="Y980_0174"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0174, (MTCI28.14) Mce1F; belongs to 24-membered
                     Mycobacterium tuberculosis Mce protein family (see
                     citations below), similar to Mycobacterium tuberculosis
                     proteins O07784|Rv0594|MTCY19H5.28c|mce2F (516 aa);
                     O53972|Rv1971|MTV051.09|mce3F (437 aa); etc. Also highly
                     similar to others e.g. NP_302661.1|NC_002677 putative
                     secreted protein from Mycobacterium leprae (516 aa);
                     AAF74993.1|AF143400_1|AF143400|996A027a protein from
                     Mycobacterium avium (80 aa) (similarity on C-terminus);
                     CAC12793.1|AL445327 putative secreted protein from
                     Streptomyces coelicolor (433 aa); etc. Has hydrophobic
                     stretch, possibly a signal peptide at the N-terminus.
                     Predicted to be an outer membrane protein (See Song et
                     al.,2008)."
                     /transl_table=11
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="UniProtKB/TrEMBL:L0T2W6"
BEGIN
        1 MLTRFIRRQL ILFAIVSVVA IVVLGWYYLR IPSLVGIGQY TLKADLPASG GLYPTANVTY
       61 RGITIGKVTA VEPTDQGARV TMSIASNYKI PVDASANVHS VSAVGEQYID LVSTGAPGKY
      121 FSSGQTITKG TVPSEIGPAL DNSNRGLAAL PTEKIGLLLD ETAQAVGGLG PALQRLVDST
      181 QAIVGDFKTN IGDVNDIIEN SGPILDSQVN TGDQIERWAR KLNNLAAQTA TRDQNVRSIL
      241 SQAAPTADEV NAVFSGVRDS LPQTLANLEV VFDMLKRYHA GVEQLLVFLP QGAAIAQTVL
      301 TPTPGAAQLP LAPAINYPPP CLTGFLPASE WRSPADTSPR PLPSGTYCKI PQDAQLQVRG
      361 ARNIPCVDVL GKRAATPKEC RSKDPYVPLG TNPWFGDPNQ ILTCPAPGAR CDQPVKPGLV
      421 IPAPSINTGL NPAPADQVQG TPPPVSDPLQ RPGSGTVQCN GQQPNPCVYT PTSGPSAVYS
      481 PASGELVGPD GVKYAVANSS TTGDDGWKEM LAPAS
//