LOCUS       AJF01515.1               289 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena Conserved integral
            membrane protein YrbE1B protein.
ACCESSION   CP007027-171
PROTEIN_ID  AJF01515.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="yrbE1B"
                     /locus_tag="Y980_0168"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0168, (MTCI28.08) YrbE1B, unknown integral
                     membrane protein, part of mce1 operon and member of YrbE
                     family (see citations below), highly similar to
                     Mycobacterium tuberculosis proteins
                     O07790|Rv0588|MTCY19H5.34|yrbE2B (295 aa);
                     O53966|Rv1965|MTV051.03|yrbE3B (271 aa); etc. Also highly
                     similar to conserved hypothetical integral membrane
                     proteins of the yrbEB type, e.g. NP_302655.1|NC_002677
                     conserved membrane protein from Mycobacterium leprae (289
                     aa); P45030|YRBE_HAEIN|HI1086 hypothetical protein from
                     Haemophilus influenzae (261 aa); etc."
                     /transl_table=11
                     /db_xref="InterPro:IPR003453"
                     /db_xref="UniProtKB/TrEMBL:L0T2Q9"
BEGIN
        1 MSTAAVLRAR FPRAVANLRQ YGGAAARGLD EAGQLTWFAL TSIGQIAHAL RYYRKETLRL
       61 IAQIGMGTGA MAVVGGTVAI VGFVTLSGSS LVAIQGFASL GNIGVEAFTG FFAALINVRI
      121 AGPVVTGVAL AATVGAGATA ELGAMRISEE IDALEVMGIK SISFLASTRI MAGLVVIIPL
      181 YALAMIMSFL SPQITTTVLY GQSNGTYEHY FQTFLRPDDV FWSFLEALII TAIVMVSHCY
      241 YGYAAGGGPV GVGEAVGRSM RFSLVSVQVV VLFAALALYG VDPNFNLTV
//