LOCUS       AJF01475.1               340 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena Secreted antigen
            85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl
            transferase 85C) (fibronectin-binding protein C) protein.
ACCESSION   CP007027-131
PROTEIN_ID  AJF01475.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="fbpC"
                     /locus_tag="Y980_0129c"
                     /gene_synonym="85C"
                     /gene_synonym="fbpC2"
                     /gene_synonym="mpt45"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0129c, (MT0137, MTCI5.03c) FbpC (alternate gene
                     names: mpt45, 85C, fbpC2), secreted antigen 85c
                     (fibronectin-binding protein C) (mycolyl transferase 85C)
                     (see citations below), also highly similar to other
                     Mycobacterial antigen precursors e.g. A85C_MYCLE|Q05862
                     antigen 85-c precursor (85c) from Mycobacterium leprae
                     (333 aa); etc."
                     /transl_table=11
                     /db_xref="GOA:P0A4V4"
                     /db_xref="InterPro:IPR000801"
                     /db_xref="PDB:1DQY"
                     /db_xref="PDB:1DQZ"
                     /db_xref="PDB:1VA5"
                     /db_xref="PDB:3HRH"
                     /db_xref="UniProtKB/Swiss-Prot:P0A4V4"
BEGIN
        1 MTFFEQVRRL RSAATTLPRR LAIAAMGAVL VYGLVGTFGG PATAGAFSRP GLPVEYLQVP
       61 SASMGRDIKV QFQGGGPHAV YLLDGLRAQD DYNGWDINTP AFEEYYQSGL SVIMPVGGQS
      121 SFYTDWYQPS QSNGQNYTYK WETFLTREMP AWLQANKGVS PTGNAAVGLS MSGGSALILA
      181 AYYPQQFPYA ASLSGFLNPS EGWWPTLIGL AMNDSGGYNA NSMWGPSSDP AWKRNDPMVQ
      241 IPRLVANNTR IWVYCGNGTP SDLGGDNIPA KFLEGLTLRT NQTFRDTYAA DGGRNGVFNF
      301 PPNGTHSWPY WNEQLVAMKA DIQHVLNGAT PPAAPAAPAA
//